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DRI DIETARY REFERENCE INTAKES FOR Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride
TABLE 7-1 Vitamin D Intake and Blood and Urinary Parameters in Adults Taking Vitamin D Supplements
Vitamin D Intake (IU/day)
Duration
Serum Calcium (mmol/L)
Serum 25(OH)D (nmol/L)
Serum Creatinine (µmol/liter)
Urinary Calcium (mmol/liter GFR)
Study
800
4–6 months
NCaa
60-105 (5 studies; n = 188)
—
—
Byrne et al., 1995
1,800
3 months
NCa
65, 80 (2 studies; n = 55)
—
—
Byrne et al., 1995
1,800
3 months
NCa
57–86
82.4–83.8
—
Honkanen et al., 1990
2,000
6 months
NCa
—
—
—
Johnson et al., 1980
10,000
4 weeks
—
105b
—
—
Stamp et al., 1977
10,000
10 weeks
—
110b
—
—
Davies et al., 1982
20,000
4 weeks
—
150b
—
—
Stamp et al., 1977
50,000
6 weeks
3.75
320
388
—
Schwartzman and Franck, 1987
50,000
15 years
3.12
560
—
—
Davies and Adams, 1978
100,000
10 years
3.20
865
215
0.508
Selby et al., 1995
200,000
2 years
3.78
1202
207
—
Selby et al., 1995
300,000
6 years
3.30
1692
184
0.432
Rizzoli et al., 1994
300,000
3 weeks
2.82
800
339
0.065
Rizzoli et al., 1994
Vitamin D poisoning
4.0 (n = 11)
1162 (n = 11)
—
—
Pettifor et al., 1995
Overfortification of milk
3.28 (n = 35)
560 (n = 35)
—
—
Blank et al., 1995
Reference levels
2.15–2.65
20–100 (10)
25–200 (9)
18–150
< 0.045
Blank et al., 1995
Haddad, 1980
a NCa = normo-calcemic.
b Indicates extrapolation from graphic data.