Biomarkers and Occupational Health: Progress and Perspectives (1995)

Biomarkers and Occupational Health: Progress and Perspectives
View larger
  • Status: Final Book
Biomarkers and Occupational Health:
Progress and Perspectives
(1995)
Purchase Options
Purchase Options MyNAP members save 10% online. Login or Register
Overview
Contractual obligations prohibit us from offering a free PDF of this title published under the Joseph Henry Press imprint of the National Academies Press. The views expressed in this book are solely those of the author(s) and do not necessarily reflect the views of the National Academies.

Authors

Description

Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers suitable for widespread use? How can they be deployed in diverse contexts? How can biological information about workers be handled fairly and ethically?

Biomarkers and Occupational Health describes the state of biomarker development, including the implications of the Human Genome program, and presents a range of viewpoints on the future of biomarkers from the leaders in the field.

This book explores the three basic types of biomarkers (markers of exposure, markers of health effects, and markers of susceptibility to disease) from a variety of perspectives. It examines what can be learned from well-known exposure sites--Hiroshima and Nagasaki, Chernobyl, and the Hanford nuclear site in the United States, for example--and a wide range of human cases and animal studies. The book also explores the costs and ramifications of developing a large-scale program to monitor potentially exposed workers (e.g., at a cleanup site).

A framework is offered for the use of biomarkers based on the mandate to "change the environment before you change the worker." The book explores how to identify ethical issues, how to set development priorities, and how to integrate biomarkers into an occupational health and safety program.

The authors present the latest technical findings about markers for chronic beryllium disease as well as markers for exposure to carcinogens, radiation, and chronium--including prospects for detecting long-past exposures.

Biomarkers and Occupational Health offers an update on biomarker development and explores a wide scope of issues. This book will be important to occupational health professionals, biomedical researchers, toxicologists, epidemiologists, and labor and management officials involved in worker health issues.

Moritmer L. Mendelsohn, M.D., Ph.D., is Vice-Chairman of the Radiation Effects Research Foundation (RERF) in Japan, which studies the long-term health effects of the atomic blasts in Hiroshima and Nagasaki, and he is former Associate Director of the Lawrence Livermore National Laboratory in California.

John P. Peeters, Ph.D., is a geneticist who is currently directing a division of the Office of Occupational Medicine for the United States Department of Energy.

Mary Janet Normandy, Ph.D., is a toxicologist who specializes in the metabolism of xenobiotics in mammalian systems. She is currently a member of the Department of Energy's Office of Occupational Medicine.

Topics

Publication Info

350 pages | 6 x 9
ISBNs:
  • Hardcover: 978-0-309-05187-3
  • Pdf full book: 978-0-309-56875-3

Table of Contents

skim chapter
Related Resources
Research Tools

Suggested Citation

National Research Council. Biomarkers and Occupational Health: Progress and Perspectives. Washington, DC: The National Academies Press, 1995.

Import this citation to:

Copyright Information

The National Academies Press (NAP) has partnered with Copyright Clearance Center's Rightslink service to offer you a variety of options for reusing NAP content. Through Rightslink, you may request permission to reprint NAP content in another publication, course pack, secure website, or other media. Rightslink allows you to instantly obtain permission, pay related fees, and print a license directly from the NAP website. The complete terms and conditions of your reuse license can be found in the license agreement that will be made available to you during the online order process. To request permission through Rightslink you are required to create an account by filling out a simple online form. The following list describes license reuses offered by the National Academies Press (NAP) through Rightslink:

  • Republish text, tables, figures, or images in print
  • Post on a secure Intranet/Extranet website
  • Use in a PowerPoint Presentation
  • Distribute via CD-ROM
  • Photocopy

Click here to obtain permission for the above reuses. If you have questions or comments concerning the Rightslink service, please contact:

Rightslink Customer Care
Tel (toll free): 877/622-5543
Tel: 978/777-9929
E-mail: customercare@copyright.com
Web: http://www.rightslink.com

To request permission to distribute a PDF, please contact our Customer Service Department at 800-624-6242 for pricing.

To request permission to translate a book published by the National Academies Press or its imprint, the Joseph Henry Press, please click here to view more information.

Related Books more