(NAS Colloquium) Genetic Engineering of Viruses and Viral Vectors
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Publication Info

144 pages | 8.5 x 11

Table of Contents

skim chapter
Contents i-ii
Genetic engineering of viruses and of virus vectors: A preface 11287-11287
Site-specific integration by adeno-associated virus 11288-11294
Oncogenic potential of the adenovirus E4orf6 protein 11295-11301
Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma 11302-11306
The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors 11307-11312
The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors 11313-11318
Replication-defective herpes simplex virus vectors for gene transfer in vivo 11319-11320
A deletion mutant in the human cytomegalovirus gene encoding IEl 49laa is replication defective due to a failure in autoregulation 11321-11326
Human cytomegalovirus U53 impairs transport and maturation of major histocompatibility complex class I heavy chains 11327-11333
Epstein-Barr virus vectors for gene delivery to B lymphocytes 11334-11340
Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety 11341-11348
Applications of pox virus vectors to vaccination: An update 11349-11353
Negative-strand RNA viruses: Genetic engineering and applications 11354-11358
Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus particles 11359-11365
Specific infection of CD4+ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein 11366-11370
Alphavirus-based expression vectors: Strategies and applications 11371-11377
Early events in poliovirus infection: Virus-receptor interactions 11378-11381
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector 11382-11388
Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesviruses 11389-11394
Development of HIV vectors for anti-HIV gene therapy 11395-11399
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes 11400-11406
Cell-surface receptors for retroviruses and implications for gene transfer 11407-11413
Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease 11414-11420
Fusigenic viral liposome for gene therapy in cardiovascular diseases 11421-11425
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Suggested Citation

National Academy of Sciences. (NAS Colloquium) Genetic Engineering of Viruses and Viral Vectors. Washington, DC: The National Academies Press, 1996.

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