Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife.
This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decisionmakers.
This authoritative volume:
- Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans.
- Examines whether and how exposure to hormonally active agents occurs--in diet, in pharmaceuticals, from industrial releases into the environment--and why the debate centers on estrogens.
- Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature.
The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
"[This book] is complete and well referenced and is truly an authoritative treatise. The serious reader will come away from the book with an understanding of the subject and its complexity up to the late 1990s. ...The book belongs in the library of every scientist, student and policymaker concerned with environmental safety, ecological integrity, and sustainable development. It is profoundly important (and very reasonably priced)."
--Journal of Environmental Quality, Jan-Feb 2001
"The numerous tables are easy to read and an excellent overview of the data discussed in each of the chapters. ...this book is a good resource for those who wish to get an overview on the topic. The references cited are an excellent starting place for more in-depth coverage ... One strength of this publication is that each chapter ends with specific recommendations for points of further research, monitoring or assessment."
--Ecology, January 2001