Drinking Water and Health, Volume 9

Selected Issues in Risk Assessment

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Size: 284 pages, 6 x 9

Publication Year:1989

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PAPERBACK ISBN-10: 0-309-03897-9 ISBN-13: 978-0-309-03897-3	$29.95	Add to Cart

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Authors:
Safe Drinking Water Committee, National Research Council
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The National Research Council closes the landmark series Drinking Water and Health with Volume 9, published in two parts:
Part I: DNA Adducts provides an overview of DNA adducts and their effects on human health, explores the techniques currently in use ...
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Table of Contents
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Front Matter	i-xiv
Part I: DNA Adducts	1-2	(skim)
Executive Summary	3-5	(skim)
1 Biologic Significance of DNA Adducts and Protein Adducts	6-37	(skim)
2 DNA-Adduct Technology	38-56	(skim)
3 Conclusions and Recommendations	57-60	(skim)
Appendix A: Drinking Water Contaminant Candidates for Development of Baseline Data on Formation of DNA Adducts	61-78	(skim)
Glossary	79-88	(skim)
Biographical Sketches	89-92	(skim)
Part II: Mixtures	93-94	(skim)
Executive Summary	95-100	(skim)
1 Introduction	101-107	(skim)
2 Pharmacokinetics and the Risk Assessment of Drinking Water Contaminants	108-120	(skim)
3 Risk Assessment of Mixtures of Systemic Toxicants in Drinking Water	121-132	(skim)
4 Assessment of Exposure to Organophosphorus Conpounds, Carbamates, and Volatile Organic Chemicals	133-145	(skim)
5 Acetylcholinesterase Inhibitors: Case Study of Mixtures of Contaminates with Similar Biologic Effects	146-161	(skim)
6 Volatile Organic Compounds (VOCs): Risk Assessment of Mixtures of Potentially Carcinogenic Chemicals	162-167	(skim)
7 Conclusions and Recommendations for Research	168-170	(skim)
Appendix A: An Approach for Risk Assessment of Volatile Organic Chemicals in Drinking Water That Uses Experimental Inhalation Data and a Physiologically Based Pharmacokinetic Model	171-174	(skim)
Appendix B: A Model Illustrating Synergism	175-176	(skim)
Appendix C: Models of Response: Dose Additivity and Response Additivity	177-181	(skim)
Biographical Sketches	182-184	(skim)
Part III: Cumulative Index	185-186	(skim)
Index	187-268	(skim)

Description

The National Research Council closes the landmark series Drinking Water and Health with Volume 9, published in two parts:
Part I: DNA Adducts provides an overview of DNA adducts and their effects on human health, explores the techniques currently in use for detecting them, offers an outlook on future toxicity testing, and lists specific recommendations for action.
Part II: Mixtures explores the issues surrounding multiple-chemical exposure from drinking water and reviews options for grouping compounds so their toxicity in mixtures can be reliably assessed. The book describes alternative approaches and considers the option of developing a modified "hazard index" for chemical compounds.

Drinking Water and Health, Volume 9

Selected Issues in Risk Assessment

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