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Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products
TABLE 4 A Sampling of Undeveloped Marine Compounds with Significant Indications of Efficacy
Marine Source
Compounds
Potential Uses
Reference
Sponge Trachycladus
Onnamide F atode worm
Antifungal, antinem
Vuong et al., 2001
Sponge Aka
Kynureninase inhibitors serotonin sulfate
Neuroprotectants for use in AIDS-dementia and stroke
Feng et al., 2000
Cyanobacterium Lyngbya
Hermitamides A, B
Anticancer
Tan et al., 2000
Sponge
Axisonitrile-3
AntiTuberculosis
König et al., 2000
Sea whip Pseudopterogorgia
Pseudopteroxazole
AntiTuberculosis
Rodriguez et al., 1999
Sponge Ircinia
Cheilanthane sesterterpenoids
Kinase inhibitors, multiple uses
Buchanan et al., 2001
Fungus Acremonium
Oxepinamide
Antiinflammatory
Belofsky et al., 2000
Fungus Acremonium
Fumiquinazoline
Antifungal
Belofsky et al., 2000
Natural source
Polycyclic acridines
Drug resistant lung cancer
Stanslas et al., 2000
Hydroid
Tridentatol A
Antioxidant inhibits LDL lipid peroxidation (superior to vitamin E)