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Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001)
Food and Nutrition Board (FNB)
Institute of Medicine (IOM)

Citation Manager

. "2 Overview and Methods." Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: The National Academies Press, 2001.

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Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
Ages 7 through 12 Months

Except for iron and zinc, during the period of infant growth and gradual weaning to a mixed diet of human milk and solid foods from ages 7 through 12 months, there is no evidence for markedly different nutrient needs. The AI can be derived for this age group by calculating the sum of (1) the content of the nutrient provided by 0.6 L/day of human milk, which is the average volume of milk reported from studies of infants receiving human milk in this age category (Heinig et al., 1993) and (2) that provided by the usual intakes of complementary weaning foods consumed by infants in this age category. Such an approach is in keeping with the current recommendations of the Canadian Paediatric Society (Health Canada, 1990), the American Academy of Pediatrics (AAP, 1997), and the Institute of Medicine (IOM, 1991) for continued feeding of infants with human milk through 9 to 12 months of age with appropriate introduction of solid foods. The amounts of vitamin A, copper, iron, and zinc consumed from complementary foods were determined by using Third National Health and Nutrition Examination Survey data, and they are discussed in the nutrient chapters.

For some of the nutrients, two other approaches were considered as well: (1) extrapolation downward from the EAR for young adults by adjusting for metabolic or total body size and growth and adding a factor for variability and (2) extrapolation upward from the AI for infants ages 0 through 6 months by using the same type of adjustment. Both of these methods are described below. The results of the methods are compared in the process of setting the AI.

Human milk does not provide sufficient levels of iron and zinc for proper growth and development of the older infant. Because factorial data were available for iron and zinc in the older infants, an EAR for iron and zinc has been established for infants ages 7 through 12 months.

Method for Extrapolating Data from Adults to Infants and Children

Setting the EAR or AI for Children

For vitamin A, chromium, copper, iodine, and molybdenum, data were not available to set the EAR and Recommended Dietary Allowance (RDA) or an AI for children ages 1 year and older and adolescents. Therefore, the EAR or AI has been extrapolated down by

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Front Matter (R1-R24)
Summary (1-28)
1 Introduction to Dietary Reference Intakes (29-43)
2 Overview and Methods (44-59)
3 A Model for the Development of Tolerable Upper Intake Levels (60-81)
4 Vitamin A (82-161)
5 Vitamin K (162-196)
6 Chromium (197-223)
7 Copper (224-257)
8 Iodine (258-289)
9 Iron (290-393)
10 Manganese (394-419)
11 Molybdenum (420-441)
12 Zinc (442-501)
13 Arsenic, Boron, Nickel, Silicon, and Vanadium (502-553)
14 Uses of Dietary Reference Intakes (554-579)
15 A Research Agenda (580-586)
Appendix A Origin and Framework of the Development of Dietary Reference Intake (587-590)
Appendix B Acknowledgments (591-593)
Appendix C Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 (594-643)
Appendix D Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994-1996 (644-653)
Appendix E Dietary Intake Data from the U.S. Food and Drug Administration Total Diet Study, 1991-1997 (654-673)
Appendix F Canadian Dietary Intake Data, 1990 (674-679)
Appendix G Biochemical Indicators for Iron, Vitamin A, and Iodine from the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 (680-691)
Appendix H Comparison of Vitamin A and Iron Intake and Biochemical Indicators from the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 (692-696)
Appendix I Iron Intakes and Estimated Percentile of the Distribution of Iron Requirements from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994-1996 (697-703)
Appendix J Glossary and Acronyms (704-708)
Appendix K Conversion of Units (709-709)
Appendix L Options for Dealing with Uncertainties (710-714)
Appendix M Biographical Sketches of Panel and Subcommittee Members (715-728)
Index (729-769)
Summary Table, Dietary Reference Intakes: Recommended Intakes for Individuals, Vitamins (770-771)
Summary Table, Dietary Reference Intakes: Recommended Intakes for Individuals, Elements (772-773)