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Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (2001)
Food and Nutrition Board (FNB)
Institute of Medicine (IOM)

Citation Manager

. "14 Uses of Dietary Reference Intakes." Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: The National Academies Press, 2001.

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Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc

TABLE 14-3 Qualitative Bioavailability of Zinc According to Diet Characteristicsa

Bioavailability

Dietary Characteristics

High

Refined diets low in cereal fiber and phytic acid, with adequate protein primarily from meats and fish

Phytate/zinc molar ratio < 5

Medium

Mixed diets containing animal or fish protein

Vegetarian diets not based primarily on unrefined, unfermented cereal grains

Phytate/zinc molar ratio 5–15

Low

Diets high in unrefined, unfermented, and ungerminated cereal grains, especially when animal protein intake is negligible

High-phytate soy protein products are the primary protein source

Diets in which ≥ 50 percent of energy is provided by high phytate foods (high extraction rate [90 percent] flours and grains, legumes)

Phytate/zinc molar ratio > 15

High intake of inorganic calcium (> 1 g/day) potentiates the inhibitory effects of these diets, especially when animal protein intake is low

a The phytate content of foods is provided by Hallberg and Hulthen (2000). The zinc content of foods is available from the U.S. Department of Agriculture at http://www.nal.usda.gov/fnic/foodcomp.

SOURCE: Modified from WHO (1996).

tiles for intake were less than 40 mg/day for all adults in both the NHANES III and CSFII surveys), when intake from supplements is added, higher proportions are above the UL. This is not unexpected, as many multiple vitamin-mineral supplements contain 15 mg of zinc. On the other hand, zinc intakes below the EAR are also fairly common. The dilemma, then, is how to ensure adequate zinc nutriture in the population while avoiding intakes in excess of the UL. Even in populations with low mean zinc intakes, care must be taken not to intervene in ways that would move a substantial proportion of the population above the UL. For example, widespread fortification of the food supply with zinc may not be appropriate, even if the prevalence of inadequacy in a population is high. More targeted approaches, such as increased consumption of zinc-rich foods by those at a high risk of inadequacy, should be considered.

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Front Matter (R1-R24)
Summary (1-28)
1 Introduction to Dietary Reference Intakes (29-43)
2 Overview and Methods (44-59)
3 A Model for the Development of Tolerable Upper Intake Levels (60-81)
4 Vitamin A (82-161)
5 Vitamin K (162-196)
6 Chromium (197-223)
7 Copper (224-257)
8 Iodine (258-289)
9 Iron (290-393)
10 Manganese (394-419)
11 Molybdenum (420-441)
12 Zinc (442-501)
13 Arsenic, Boron, Nickel, Silicon, and Vanadium (502-553)
14 Uses of Dietary Reference Intakes (554-579)
15 A Research Agenda (580-586)
Appendix A Origin and Framework of the Development of Dietary Reference Intake (587-590)
Appendix B Acknowledgments (591-593)
Appendix C Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 (594-643)
Appendix D Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994-1996 (644-653)
Appendix E Dietary Intake Data from the U.S. Food and Drug Administration Total Diet Study, 1991-1997 (654-673)
Appendix F Canadian Dietary Intake Data, 1990 (674-679)
Appendix G Biochemical Indicators for Iron, Vitamin A, and Iodine from the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 (680-691)
Appendix H Comparison of Vitamin A and Iron Intake and Biochemical Indicators from the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994 (692-696)
Appendix I Iron Intakes and Estimated Percentile of the Distribution of Iron Requirements from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994-1996 (697-703)
Appendix J Glossary and Acronyms (704-708)
Appendix K Conversion of Units (709-709)
Appendix L Options for Dealing with Uncertainties (710-714)
Appendix M Biographical Sketches of Panel and Subcommittee Members (715-728)
Index (729-769)
Summary Table, Dietary Reference Intakes: Recommended Intakes for Individuals, Vitamins (770-771)
Summary Table, Dietary Reference Intakes: Recommended Intakes for Individuals, Elements (772-773)