Appendix C
2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products

AGENDA

The National Academies

2101 Constitution Avenue, NW

Washington, D.C. 20418

MONDAY, November 5, 2001

8:00 a.m.

Breakfast

8:30 a.m.

Introductions and welcome —Nancy Targett, Committee Chair, University of Delaware, Jennifer Merrill, Study Director, Ocean Studies Board

SESSION 1: DRUG DISCOVERY AND DEVELOPMENT

8:45 a.m.

Session chairs—Shirley Pomponi, Harbor Branch Oceanographic Institute, William Gerwick, Oregon State University

8:55 a.m.

Accessing new materials: Supply issues, uncultured species—William Fenical, Scripps Institution of Oceanography



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OCR for page 109
Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products Appendix C 2001 Marine Biotechnology Workshop: Biomedical Applications of Marine Natural Products AGENDA The National Academies 2101 Constitution Avenue, NW Washington, D.C. 20418 MONDAY, November 5, 2001 8:00 a.m. Breakfast 8:30 a.m. Introductions and welcome —Nancy Targett, Committee Chair, University of Delaware, Jennifer Merrill, Study Director, Ocean Studies Board SESSION 1: DRUG DISCOVERY AND DEVELOPMENT 8:45 a.m. Session chairs—Shirley Pomponi, Harbor Branch Oceanographic Institute, William Gerwick, Oregon State University 8:55 a.m. Accessing new materials: Supply issues, uncultured species—William Fenical, Scripps Institution of Oceanography

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Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products 9:25 a.m. Discussion 9:35 a.m. Novel screening directions and technologies: Analytical techniques, retrospective views, development bottlenecks—Guy Carter, Wyeth Ayerst 10:05 a.m. Discussion 10:15 a.m. Break 10:30 a.m. The oceans: A rich source of drugs to treat human disease—Mary Ann Jordan, University of California, Santa Barbara 11:00 a.m. Discussion 11:10 a.m. Ecological roles: Mechanisms for discovery of novel targets, comparative biochemistry—Patrick Walsh, Rosenstiel School of Marine and Atmospheric Science 11:40 a.m. Discussion 11:50 a.m. Molecular biology and natural products—Bradley Moore, University of Arizona 12:20 p.m. Discussion 12:30 p.m. Lunch SESSION 2: GENOMIC AND PROTEOMIC APPLICATIONS FOR MARINE BIOPRODUCT DISCOVERY 1:30 p.m. Session chairs—D. Jay Grimes, University of Southern Mississippi, John Heidelberg, The Institute for Genomic Research 1:40 p.m. The genomics revolution: Challenges and opportunities— Claire Fraser, The Institute for Genomic Research

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Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products 2:10 p.m. Discussion 2:20 p.m. Bringing culture to the uncultured: Microbial discovery by high throughput cultivation—Stephen Giovannoni, Oregon State University 2:50 p.m. Discussion 3:00 p.m. Microbial microarrays: Utility, limitations and future applications, lessons learned from several model systems—Scott Peterson, The Institute for Genomic Research 3:30 p.m. Discussion 3:40 p.m. Break 4:00 p.m. Microbial genomics: Where do we go now?—Daniel Drell, U.S. Department of Energy 4:30 p.m. Discussion 4:40 p.m. Summary discussion of events, led by Nancy Targett 5:15 p.m. Reception – Rotunda 6:00 p.m. Evening lecture—Marine biotechnology, past, present and future—Rita R. Colwell, National Science Foundation 6:45 p.m. Discussion 7:30 p.m. Workshop adjourns for the day TUESDAY, November 6, 2001 8:00 a.m. Breakfast 8:30 a.m. Introductions—Dr. Nancy Targett, University of Delaware

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Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products SESSION 3: BIOMATERIALS AND BIOENGINEERING 8:45 a.m. Session chairs—Roger Prince, ExxonMobil Research, Robert Baier, SUNY Buffalo 8:55 a.m. Bioadhesives: Biocatalysis, post translational modification—Christine Benedict, Geneva Pharmaceuticals, Inc. 9:25 a.m. Discussion 9:35 a.m. Self-cleaning surfaces: Biolubricants, drag reduction— Anne Meyer, State University of New York at Buffalo 10:05 a.m. Discussion 10:15 a.m. Break 10:30 a.m. Uniform microporous biomaterials prepared from marine skeletal precursors—Rodney White, UCLA Medical Center 11:00 a.m. Discussion 11:10 a.m. Polymers for tissue engineering: Drug delivery and cellular therapy—Cato Laurencin, Drexel University 11:40 p.m. Discussion 12:00 p.m. Lunch SESSION 4: PUBLIC POLICY, PARTNERSHIPS, AND OUTREACH 12:50 p.m. Session chairs—Nancy Targett, Committee Chair, University of Delaware, Jennifer Merrill, Ocean Studies Board

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Marine Biotechnology in the Twenty-First Century: Problems, Promise, and Products 1:00 p.m. Biomedical compounds extracted from coral reef organisms: Harvest pressure, conservation concerns, and sustainable management—Andrew Bruckner, NOAA Office of Protected Resources 1:30 p.m. Discussion 1:40 p.m. Productive partnerships in natural products discovery and development—Joshua Rosenthal, Fogarty Center (NIH) 2:10 p.m. Discussion 2:20 p.m. Break 2:30 p.m. Commercialization of marine bioproducts: Intellectual property and technology transfer issues—Donald Gerhart, University of Oregon 3:00 p.m. Discussion 3:10 p.m. Planning, partnerships, and progress in marine biotechnology research and outreach in Florida—James Cato, University of Florida Sea Grant Program 3:40 p.m. Discussion 3:50 p.m. Workshop wrap-up Session chairs present 10-minute summaries of the topics discussed 4:30 p.m. Final discussion of the topic 5:30 p.m. Workshop adjourns