sodium chloride per day, increasing dietary potassium as potassium bicarbonate to an intake of 6.6 g (170 mmol)/day abolished the salt sensitivity of all subjects (Schmidlin et al., 1999).
In aggregate, these trials document that supplemental potassium bicarbonate mitigates the pressor effect of dietary sodium chloride in a dose-dependent fashion. Furthermore, these trials highlight the potential benefit of increased potassium intake in African Americans, who have a higher prevalence of hypertension and of salt sensitivity and a lower intake of potassium than non-African Americans. Survey data from the Third National Health and Nutrition Examination Survey (NHANES III) in the United States (Appendix Tables D-6 and D-7) estimated that the median intake of potassium of non-Hispanic African-American men (aged 19 to 30 years) was 3.0 g (78 mmol)/day, while that for non-Hispanic white men (aged 19 to 30 years) was 3.4 g (87 mmol)/day, approximately 10 percent lower than their white counterparts. Similar differences