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Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005)
Food and Nutrition Board (FNB)

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. "5 Potassium." Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: The National Academies Press, 2005.

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Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate

TABLE 5-4 Clinical Trials on the Effects of Potassium Supplements on Blood Pressure in Nonhypertensive Individuals in Order of Increasing Duration of Intervention

Reference

Subjects

Study Design

Potassium Intake,b g/d (mmol/d)

Barden et al., 1991a

37 women

4-d crossover

Placebo

3.1 (80) KCl supplement

Gallen et al., 1998

10 men, 11 women

9-d crossover; K restriction; 4.1 g (180 mmol) Na

0.78 (20) diet plus placebo

3.1 (80) KCl supplement

Krishna et al., 1989a

10 men

10-d crossover; 2.8–4.6 (120–200 mmol) Na

0.4 (10) diet plus placebo

3.5 (90) [80 KCl supplement]

Skrabal et al., 1981a

20 men

2-wk crossover

3.1 (80) KCl supplement [4.6 (200) Na]

3.1 (80) KCl supplement [1.2 (50) Na]

7.8 (200) KCl supplement [4.6 (200) Na]

7.8 (200) KCl supplement [1.2 (50) Na]

Khaw and Thom, 1982a

20 men

2-wk crossover

1.6 (41) diet

2.5 (64) KCl supplement

Poulter and Sever, 1986a

19 men

2-wk crossover

Placebo

2.5 (64) KCl supplement

Mullen and O’Connor, 1990a

24 men

2-wk crossover

Placebo

2.9 (75) KCl supplement

2.9 (75) K citrate supplement

Brancati et al., 1996a

31 men, 56 women

3-wk parallel, 2.9–4.0g (127–175 mmol) Na

Placebo plus 1.3-1.4 (32-35) K from diet

3.1 (80) KCl supplement plus 1.3-1.4 (32-35) K from diet

Page
204
Front Matter (R1-R20)
Summary (1-20)
1 Introduction to Dietary Reference Intakes (21-36)
2 Overview and Methods (37-49)
3 A Model for the Development of Tolerable Upper Intake Levels (50-72)
4 Water (73-185)
5 Potassium (186-268)
6 Sodium and Chloride (269-423)
7 Sulfate (424-448)
8 Applications of Dietary Reference Intakes for Electrolytes and Water (449-464)
9 A Research Agenda (465-470)
Appendix A: Glossary and Acronyms (471-476)
Appendix B: Origin and Framework of the Development of Dietary Reference Intakes (477-484)
Appendix C: Predictions of Daily Water and Sodium Requirements (485-493)
Appendix D: U.S. Dietary Intake Data from the Third National Health and Nutrition Examination Survey, 1988–1994 (494-517)
Appendix E: U.S. Dietary Intake Data for Water and Weaning Foods from the Continuing Survey of Food Intakes by Individuals, 1994–1996, 1998 (518-526)
Appendix F: Canadian Dietary Intake Data for Adults from Ten Provinces, 1990–1997 (527-533)
Appendix G: U.S. Water Intake and Serum Osmolality Data from the Third National Health and Nutrition Examination Survey, 1988–1994 (534-536)
Appendix H: U.S. Total Water Intake Data by Frequency of Leisure Time Activity from the Third National Health and Nutrition Examination Survey, 1988–1994 (537-545)
Appendix I: Dose-Response Effects of Sodium Intake on Blood Pressure (546-557)
Appendix J: Serum Electrolyte Concentrations NHANES III, 1988-94 (558-563)
Appendix K: Options for Dealing with Uncertainties (564-568)
Appendix L: Acknowledgments (569-571)
Appendix M: Biographical Sketches of Panel Members (572-576)
Index (577-618)