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TABLE 5-7 Epidemiological Studies on the Effect of Potassium Intake on Bone Mineral Density (BMD)

Reference

Study Design

Effect

Findings

New et al., 1997

Cross-sectional

944 women

+

Potassium intake was significantly (p < 0.05) correlated with BMD for lumbar spine, femoral neck, trochanter, and Ward’s area in premenopausal women

Tucker et al., 1999

Cross-sectional and longitudinal

907 men and women

+

Potassium intake was significantly (p < 0.05) associated with BMD for the femoral neck, trochanter, Ward’s area, and radius in men (cross-sectional)

In women potassium intake was significantly (p < 0.05) associated with bone mineral density for the trochanter, Ward’s area, and radius (cross-sectional)

In a 4-yr analysis of change in BMD, potassium intake was significantly (p < 0.05) associated with less decline in BMD for femoral neck and trochanter in men

New et al., 2000

Cross-sectional

62 women

+

Potassium intake was significantly (p < 0.01) associated with higher total bone mass (p < 0.05 to p < 0.005)

Potassium intake was significantly (p < 0.02) and negatively associated with pyridinoline excretion and deoxypyridinoline excretion

Jones et al., 2001

Cross-sectional

330 children

+

Significant (p < 0.001) association between urinary potassium, femoral neck, lumbar spine, and total body BMD in prepubertal children

Macdonald et al., 2004

Longitudinal

891 women

+

Significant (p < 0.05) and positive correlation between potassium intake and femoral neck BMD in premenopausal and perimenopausal women



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