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Reference
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Study Design
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Diet
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Nonhypertensive individuals
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Hene et al., 1986
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6 men, 24 ± 2 yr
2-wk crossover
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Control diet: 3.1 g (80 mmol) potassium (K), 3.4 g (150 mmol) sodium (Na)
High-K diet: 8.6 g (220 mmol) K, 3.4 g (150 mmol) Na (additional potassium as K citrate)
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Witzgall and Behr, 1986
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16 men, 27 ± 6 yr, control diet 2 wk prior to loading
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Control diet: 2.3 g (60 mmol) K, 4.6 g (200 mmol) Na
High K diet: control diet + 7.8 g (200 mmol) as K citrate and K hydrogen carbonate = 10.1 g (260 mmol) K total
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Rabelink et al., 1990
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3 men, 3 women, 22–26 yr
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5-d control diet: 3.9 g (100 mmol) K, 2.3 g (100 mmol) Na
20-d high K diet: 15.6 g (400 mmol)K, 2.3 g (100 mmol) Na
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Deriaz et al., 1991
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8 men, 26 ± 2 yr
5-d crossover
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Baseline diet: 2.7 g (69 mmol) K
High K diet: 6.4 g (163 mmol) K
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Dluhy et al., 1972
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8 women, 2 men
Crossover
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5 subjects: 0.23 g (10 mmol) Na
1.6 g (40 mmol) K, 6–7 d
7.8 g (200 mmol) K, 3 d
5 subjects: 4.6 g (200 mmol) Na
1.6 g (40 mmol) K, 6–7 d
7.8 g (200 mmol) K, 3 d
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Zoccali et al., 1985
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10 men, 20–29 yr
5-d crossover
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Baseline diet: 3.0 g (76 mmol) K, 3.4 g (145 mmol) Na
High K diet: 6.9 g (176 mmol) K, 3.4 g (145 mmol) Na
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Hypertensive individuals
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Zoccali et al., 1985
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10 men, 9 women, 26–53 yr
2-wk crossover
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Baseline diet: Normal diet + placebo
Higher K diet: + 3.9 g (100 mmol) K
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a SBP = systolic blood pressure, DBP = diastolic blood pressure.
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