APPENDIX C
International Classification of Diseases (ICD) Codes for Cancers of Interest

The International Classification of Diseases (ICD) is a system used by physicians and researchers around the world to group related disease entities and procedures for the reporting of statistical information. It is used for the purposes of classifying morbidity and mortality information for statistical purposes, indexing hospital records by disease and operations, reporting diagnosis by physicians, data storage and retrieval, reporting national morbidity and mortality data, and reporting and compiling health care data.

Many of the studies reviewed by the committee use or were written at a time when the Ninth Edition of the classifications (ICD-9) was in place. Accordingly, ICD references in this report use that scheme. The Tenth Edition (ICD-10) began to be implemented in the United States in 1999. It differs from ICD-9 in the level of detail (~8,000 categories versus ~5,000) and nomenclature (alphanumeric versus numeric codes); additions and modifications were also made to some coding rules and the rules for selecting the underlying cause of death (Anderson et al., 2001).

Table C-1 lists the ICD-9 and ICD-10 codes for the various forms of cancer addressed in the report. The listed codes are for malignant neoplasms. In situ neoplasms, benign neoplasms, neoplasms of uncertain behavior, and neoplasms of unspecified behavior have separate codes in both schemes.



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Veterans and Agent Orange: Update 2004 APPENDIX C International Classification of Diseases (ICD) Codes for Cancers of Interest The International Classification of Diseases (ICD) is a system used by physicians and researchers around the world to group related disease entities and procedures for the reporting of statistical information. It is used for the purposes of classifying morbidity and mortality information for statistical purposes, indexing hospital records by disease and operations, reporting diagnosis by physicians, data storage and retrieval, reporting national morbidity and mortality data, and reporting and compiling health care data. Many of the studies reviewed by the committee use or were written at a time when the Ninth Edition of the classifications (ICD-9) was in place. Accordingly, ICD references in this report use that scheme. The Tenth Edition (ICD-10) began to be implemented in the United States in 1999. It differs from ICD-9 in the level of detail (~8,000 categories versus ~5,000) and nomenclature (alphanumeric versus numeric codes); additions and modifications were also made to some coding rules and the rules for selecting the underlying cause of death (Anderson et al., 2001). Table C-1 lists the ICD-9 and ICD-10 codes for the various forms of cancer addressed in the report. The listed codes are for malignant neoplasms. In situ neoplasms, benign neoplasms, neoplasms of uncertain behavior, and neoplasms of unspecified behavior have separate codes in both schemes.

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Veterans and Agent Orange: Update 2004 TABLE C-1 Surveillance, Epidemiology, and End Results (SEER) Program Malignant Neoplasm Site Groupings for ICD-9 and ICD-10; National Center for Health Statistics (NCHS) Data Cancer Site ICD-9 codes ICD-10 codes Buccal cavity and pharynx Lip 140.0–140.9 C00.0–C00.9 Tongue 141.0–141.9 C01; C02.1–C02.9 Salivary glands 142.0–142.9 C07; C08.0–C08.9 Floor of mouth 144.0–144.9 C04.0–C04.9 Gum and other mouth 143.0–143.9, 145.0-145.6, 145.8-145.9 C03.0–C03.9; C05.0–C05.9; C06.0–C06.9 Nasopharynx 147.0–147.9 C11.1–C11.9 Tonsil 146.0–146.2 C09.0–C09.9 Oropharynx 146.3–146.9 C10.1–C10.9 Hypopharynx 148.0–148.9 C12; C13.0–C13.9 Other buccal cavity and pharynx 149.0–149.9 C14.0–C14.9 Digestive system Esophagus 150.0–150.9 C15.0–C15.9 Stomach 151.0–151.9 C16.0–C16.9 Small intestine 152.0–152.9 C17.0–C17.9 Colon excluding rectum 153.0–153.9, 159.0 C18.0–C18.9; C26.0 Rectum and rectosigmoid junction 154.0–154.1 C19; C20 Anus, anal canal, and anorectum 154.2–154.3, 154.8 C21.0–C21.9 Liver and intrahepatic bile duct Liver 155.0,155.2 C22.0; C22.2–C22.4; C22.7–C22.9 Intrahepatic bile duct 155.1 C22.1 Gallbladder 156.0 C23 Other biliary 156.1–156.9 C24.0–C24.9 Pancreas 157.0–157.9 C25.0–C25.9 Retroperitoneum 158.0 C48.0 Peritoneum, omentum, and mesentery 158.8–158.9 C48.1–C48.2 Other digestive organs 159.8–159.9 C26.8–26.9; C48.8 Respiratory system Nasal cavity, middle ear, and accessory sinuses 160.0–160.9 C30.0, C30.1; C31.0–C31.9 Larynx 161.0–161.9 C32.0–C32.9 Lung and bronchus 162.2–162.9 C34.0–C34.9 Pleura 163.0–163.9 C38.4 Trachea, mediastinum, and other respiratory organs 162.0, 164.2–165.9 C33; C38.1–C38.3, C38.8; C39 Bones and joints 170.0–170.9 C40.0–C40.9; C41.0–C41.9 Soft tissue (including heart) 171.0–171.9, 164.1 C38.0; C47.0–C47.9; C49.0–C49.9 Skin Malignant melanomas 172.0–172.9 C43.0–C43.9 Other malignant skin neoplasms 173.0–173.9 C44.0–C44.9

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Veterans and Agent Orange: Update 2004 Cancer Site ICD-9 codes ICD-10 codes Breast (male and female) 174.0–174.9, 175 C50.0–C50.9 Female genital system Cervix 180.0–180.9 C53.0–C53.9 Corpus 182.0–182.1, 182.8 C54.0–C54.9 Uterus, not otherwise specified 179 C55 Ovary 183.0 C56.0–C56.9 Vagina 184.0 C52 Vulva 184.1–184.4 C51.0–C51.9 Other female genital organs 181, 183.2–183.9, 184.8, 184.9 C57.0–C57.9; C58 Male genital system Prostate 185 C61 Testis 186.0–186.9 C62.0–C62.9 Penis 187.1–187.4 C60.0–C60.9 Other male genital organs 187.5–187.9 C63.0–C63.9 Urinary system Urinary bladder 188.0–188.9 C67.0–C67.9 Kidney and renal pelvis 189.0, 189.1 C64.0–C64.9; C65.0–C65.9 Ureter 189.2 C66.0–C66.9 Other urinary organs 189.3–189.4, 189.8–189.9 C68.0–C68.9 Eye and orbit 190.0–190.9 C69.0–C69.9 Brain and other nervous system Brain 191.0–191.9 C71.0–C71.9 Meninges 192.1 C70.0–C70.9 Other nervous systema 192.0, 192.2–192.9 C72.0–C72.9 Endocrine system Thyroid 193 C73 Other endocrine (including thymus) 164.0, 194.0–194.9 C37; C74.00–C74.92; C75.0–C75.9 Lymphomas Hodgkin’s disease 201.0–201.9 C81.0–81.9 Non-Hodgkin’s lymphomas 200.0–200.8, 202.0–202.2, 202.8–202.9 C82.0–C82.9; C83.0–C83.9; C84.0–C84.5; C85.0–C85.9; C96.3 Multiple myeloma 203.0; 238.6 C90.0, C90.2   Leukemias Lymphocytic Acute lymphocytic 204.0 C91.0 Chronic lymphocytic 204.1 C91.1 Other lymphocytic 202.4; 204.2–204.9 C91.2-C91.4, C91.7, C91.9 Myeloid (granulocytic) Acute myeloid 205.0; 207.0, 207.2 C92.0, C92.4–C92.5; C94.0, C94.2 Chronic myeloid 205.1 C92.1 Other myeloid 205.2–205.3, 205.8–205.9 C92.2–C92.3, C92.7, C92.9

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Veterans and Agent Orange: Update 2004 Cancer Site ICD-9 codes ICD-10 codes Monocytic Acute monocytic 206.0 C93.0 Chronic monocytic 206.1 C93.1 Other monocytic 206.2–206.9 C93.2, C93.7, C93.9 Other leukemia Other acute 208.0 C94.4, C94.5; C95.0 Other chronic 207.1, 208.1 C94.1; C95.1 Aleukemic, subleukemic and “not otherwise specified” 203.1, 207.2, 207.8, 208.2–208.9 C90.1; C91.5; C94.3, C94.7; C95.2, C95.7, C95.9 Miscellaneous malignant neoplasms 159.1, 195.0–195.8, 196.0–196.9, 199.0–199.1, 202.3, 202.5–202.6, 203.8 C26.1; C76.0–C76.8; C77.0–C77.9; C78.0–C78.8; C79.0–C79.8; C80; C88.0–C88.9; C96.0–C96.2, C96.7, C96.9; C97 a Cancers of the peripheral nerves and the autonomic nervous system are classified as “soft tissue” in the ICD. Adapted from: Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Mariotto A, Fay MP, Feuer EJ, Edwards BK (eds). SEER Cancer Statistics Review, 1975-2000, National Cancer Institute. Bethesda, MD, Table A-4. REFERENCE Anderson RN, Minino AM, Hoyert DL, Rosenberg HM. 2001. Comparability of cause of death between ICD-9 and ICD-10: preliminary estimates. National Vital Statistics Reports 49(2):1–32.