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Biological Science and Biotechnology in Russia: Controlling Diseases and Enhancing Security (2005)
Development, Security, and Cooperation (DSC)

Page
125
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Biological Science and Biotechnology in Russia: Controlling Diseases and Enhancing Security

Appendix L
List of Research Projects Proposed in Open Competitions Organized in 20031

Title of Project

Financial Support (in rubles)

Genomic micromatrices for determining the link between Helicobacter pylori and early stomach cancer

3 million

Role of oxide-modified fibrinogen and lipoproteins in the development of cardiovascular diseases and their complications

1 million

Creation of new material based on spider web protein structures

2 million

Creation of transgenic plants to serve as superproducers of targeted proteins (including those for medical use)

3.5 million

Bioinformatic approaches in biotechnology

3 million

Synthesis of biogenic surfactants with a broad range of functional characteristics

1.5 million

Biosafety of ecosystems in the Russian Federation with regard to invasive exotic species

1.5 million

Development of food product technologies based on non-standard agricultural raw materials biotransformed with the aid of multistrains and enzyme systems

900,000

1  

The competition was sponsored by the Russian Ministry of Industry and Science as part of the Priority Objective on Developing New Biotechnology Research Areas and Ensuring Biosafety. Translated from the Russian by Kelly Robbins.

Page
125
Front Matter (R1-R10)
Summary (1-9)
Introduction (10-20)
1 The Vision for Russia s Future (21-26)
2 Pillar One: Improving Surveillance and Response (27-35)
3 Pillar Two: Meeting Pathogen Research Challenges (36-46)
4 Pillar Three: The Promise of Biotechnology (47-58)
5 Pillar Four: The Human Resource Base (59-64)
6 Reshaping U.S.-Russian Cooperation in the Biological Sciences and Biotechnology (65-75)
Epilogue (76-78)
Appendix A Committee Biographies (79-85)
Appendix B Organizations Consulted During the Study (86-88)
Appendix C Decision of the Board of the Ministry of Health of the Russian Federation: Tasks for the Periods 2001-2005 and 2006-2010 from Protocol #6 (89-92)
Appendix D Main Goals and Objectives in Combating Infectious Diseases in the Russian Federation (93-95)
Appendix E Regulations on the Federal Service for the Supervision in the Sphere of Health and Social Development (96-103)
Appendix F Recent Reports by the National Academies on Global Health Concerns (104-105)
Appendix E Regulations Regarding the Federal Service for the Supervision in the Sphere of Health and Social Development (106-107)
Appendix H Highest Priority Measures for Creating a System to Counter Biological Terrorism (108-112)
Appendix I National Immunization Calendar of the Russian Federation (113-114)
Appendix J Selected Russian Research and Related Institutions with Activities Relevant to Infectious Diseases, Diagnostics, Treatment, Prevention, and Control (115-119)
Appendix K Scientific and Methodological Research Results Highlighted by the Russian Ministry of Health and Social Development (120-124)
Appendix L List of Research Projects Proposed in Open Competitions Organized in 2003 (125-126)
Appendix M Test Systems and Other Products Being Developed in Russian Laboratories (127-130)
Appendix N RosAgroBioProm Organizational Structure (131-131)
Appendix O Activities of Russian Research Institutes in Developing Vaccines for Human Use (132-132)
Appendix P Regulation of the Russian Government on Licensing Activities Connected with the Use of Infectious Disease Antidotes, No. 731 (133-136)
Appendix Q Bioengagement Programs Financed by the United States Government (137-142)
Appendix R International Programs and Projects of Special Significance to the Ministry of Health and Social Development (143-144)
Selected Bibliography (145-146)

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OCR for page 125
Biological Science and Biotechnology in Russia: Controlling Diseases and Enhancing Security Appendix L List of Research Projects Proposed in Open Competitions Organized in 20031 Title of Project Financial Support (in rubles) Genomic micromatrices for determining the link between Helicobacter pylori and early stomach cancer 3 million Role of oxide-modified fibrinogen and lipoproteins in the development of cardiovascular diseases and their complications 1 million Creation of new material based on spider web protein structures 2 million Creation of transgenic plants to serve as superproducers of targeted proteins (including those for medical use) 3.5 million Bioinformatic approaches in biotechnology 3 million Synthesis of biogenic surfactants with a broad range of functional characteristics 1.5 million Biosafety of ecosystems in the Russian Federation with regard to invasive exotic species 1.5 million Development of food product technologies based on non-standard agricultural raw materials biotransformed with the aid of multistrains and enzyme systems 900,000 1   The competition was sponsored by the Russian Ministry of Industry and Science as part of the Priority Objective on Developing New Biotechnology Research Areas and Ensuring Biosafety. Translated from the Russian by Kelly Robbins.

OCR for page 126
Biological Science and Biotechnology in Russia: Controlling Diseases and Enhancing Security Title of Project Financial Support (in rubles) Development of methods for using heat shock protein to eliminate postoperative scarring 3.5 million Study of processes involved in the synthesis of physiologically active proteins in cell-free systems 3 million Creation of a transgenic potato resistant to viroidal, viral, and bacterial infections 2.5 million Study of pharmacological properties of endogenous peptides (functional protein fragments) 4 million Development of stem cell-based technologies for cell replacement therapy 3.4 million Study of regulatory elements determining the boundaries of human genome domains and the effectiveness of their expression, as well as their use in improving genetic engineering methodologies 3.2 million Development of nuclear magnetic resonance technologies and associated software for structural-functional proteomics and bioengineering 2.5 million Development of microchip-based methods for analyzing biotoxins 2.2 million Creation of a system for targeted delivery of gene therapy constructs based on hepatitis C (HCV) virions 4 million Development of methods for three-dimensional spectral microtomography for studying cell transport and interactions of proteins and peptides 1.7 million New methods of molecular modeling and molecular dynamics for structure-function analysis of proteins and peptides 3 million Application of modern biotechnology approaches for increasing the effectiveness of anti-tumor gene therapy preparations 3 million Study of the role of serine-threonine protein kinase of actinomycetes in regulating antibiotic resistance 3.3 million Search for producers of biologically-active substances with hypolipidemic properties 2 million Synthesis and determination of the structure and biological activity of new productive fluorquinolones 2.3 million TOTAL 60 milliona aThe exchange rate in 2003 was 30.7 rubles = $1.

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