|
Items in cart [1] |
Questions? Call 888-624-8373 |
PAPERBACK Free Resources |
||||||||||||||||
|
||||||||||||||||
|
||||||||||||||||
| ||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||
| Copyright © 2009. National Academy of Sciences. All rights reserved. Terms of Use and Privacy Statement |
Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page 1
Introduction
~ 7R~tt r6!~s~9I ttel~ AlRiql Hat ~l1!(Guide for the Care and Use of
Laboratory Animals: old ill~)J Q 0~3T. ~$ ~~ ^1~q]A1 *~= ~3471
At§zE~ At2~1~°1 ~~ "~;71~ 44~ ~1°~1~ ~4~61 410t Atom ~~ T7'1~17i71 $1
3] 1~ ~ Al~DAl~ 08 ;,, ;;7*, A1~D3q|A1 ~ ~1 '~7~0T ~ cola Ado!
Al ~ Ad ~ ~51 ~ ~ 03 act Eta :~7d All ~ ~ ~1 ~1 J ~91 ~ -Al All id
~ dim .~qol~ ~s] A—~ :~79~ ^1762jLE1 A|~4~ which tt7~1~ql7
;~= ~ 'God In ~1~ql^1 g~ ~~S°~.
~ ;~l;UDAl~ Balm Aa~g]84(Biomedical science) =4 ~s~84 °~:i~. ~4~. Alma
A - ~~ ~ql if 0,11; 7A ~3~ AM I. 71~ 71"'A°~ ='A~A1
~1 ~71 AO~184 08 IL$21 ~7A off, °~ ~ ~ql ~I8~ Aa~a47g -A1=e| 79~
O CRA1~ f AA ~ 70 ~ ~ 711 O ill ~ °1 At. 20A1 71 Al ~ °1 51 e ED 7~ 7 the- ~~Q2 Am
7AQ 31~431 ~1~4 71 51ql Its ~t:dql Dow ~~ 1!I~(Leader and Stark
1987). DI ~ ~847~°1 IT. ;i7*, Al ED e $1 OR ~~ 2 AL§~17.1 ,2L ~ 2
(non-ammal modems °iA1 ~7gA171 ~71D~(NRC 1977: ~* A, r
) °1 ~7 2 2°1 *~A°,] 0~17,1 {F. ~~ BAIT At V~ f ~00 0 rip 0
7~70~ D4 ~ 7.1 by ,OAO1A1 ~ 7'1 COLA °0 ~78* 'At ~ ~°} 7A _ ~~ At
Or ~a" ~ e! {h:F ~ D Al 5 ~rTL8= ~ °.~1LqlA1 ~847 ° ~ ~~ ~ 1~
(alternatives), (adjunct Ives), 71Al~(refinements),Q 7R~7 ~~61~r~-
-~Q 71gr~R°l Cool-.
7A yAlqllAl~ IT. To* Al~DqllA1 A1.~71~ ~ ~ A, O e (°1~ ~ 1. M~ 1
!~Dr 71~r Stake falser =)8 ~~— In ~73~. ST+l
~ 7~ ram ~Q1~ She'd 7A ~'~Al~r~ ~0,]7 °~!Tq ~ °r°ll 0°1—
7~. 7~1-°~-Y'sRqlA1 ?! 3~ °lA.~*gE AM OF. Omit Al§51= MAT
Aft rR oRA1 ~ ~81 °A 70 I TV A1 ~0~7A1 ~ °~°~ ~ D] At, ~ 71 AI Al Al Par 0~ U~7
1 1 D ~~ 1 B1 J - ~~ anal 5— 7 ~ 7Q 01 ~
1. Am, TIC, 2!7;1 (Regulations, Policies and Principles)
~ i7l^AOAl~ A~o3o~71tt7J $~'q(1nteragency Research Animal Committee:
IRAC)°n 91~ rA|6O. IT ~ T;~OFqI Album Tow ~g;il J;~ ~H~ Ale
7lTQI t!&I(U.S. Government Principles for Utilization and Care of
Vertebrate Animals Used in Testing. Research, and Training(lRAC 1985:
* D Ao~Z)J Al Am! BILL 7='°1 °.]T:Z~ al no I 01170~ ol ~1 ~ (! &1~ ~
I D 1~ OR 7 ~ 7 §~Q ~84A1= 7gF77O] Al ~ ol ~ ~—Otrl ~ O~ al ~ ~8
T) OQ Ale ;QL 7~ § -
15
OCR for page 2
Lima ~~ 7
O Angola ~~ 7570~. 7'1A4~ ~~ ~8 ~~ _21~ ~r7~ 71~7
41~ ~1~ ~~
0 7 7~ ~ ~ o . ~~ n4 *atom A}*
0 7376~ arm 71~ I. I. ~04 ~7'~ ma
0 797~ 7170a 7~ ~ a ~~ ^~§
0 ~7~ A17Ro4 ~~
O 1°r71~71~1 7'1~ at Tang ~~ 7~ ~~At*~ ~~'
0 ~~ ^~°t 01~ -Crawl ~ IT. 7't74~ 7~ ~~ ~~ ~~ ~~ 747~79 7
ol al A1 ~ T ~ ~ 79
8 ~~ ~ ~~ 08T7.~ ~401Q BIAS Ott ~~ ° Aims Ott
TV r71~ ~~ Ott, A—~~ (Institutional Animal Care and Use
Committee, IACIUC: Olga ~~ l(IACUC)*~ 1})~ ~ 70~'0iql °lT°171r)
*~^l~ol~ =~.~o~ ~ 711!A1~ r*~_Al~(Animal Welfare
Regulation: AWRs)~ . rO~O~ (Code of Federal Regulations: CFR
1985)~ ~.Q I 01~7m ~4 Aims| ~~ of 70~(Public
Health Service Policy on Humane Care and Use of Laboratory Animals,
PHS policy: PHS 1996), . ~ Balm ~~ °1~(T~ C. D Aft). T ~ 74 Al
owl If 7~ TBa~o1o~ Art"'. ~70 ~~'r~ War. ~ it, An, Aim
Al tt'SJ 770 ~ ~~ r~'r~7'~ (Institute of Laboratory Animal
Resources: ILAR)~ ~ ~ 71~qlA] ~~ ~~ He A1 0] a T O (TV A Ace)
~ 7.l~A1qn 0~ If ~ 7.1~Alql if ~~" 7~IA1~7~ ~~ 8~
~°1 I.
2. ~71= (Evaluation Criteria)
1 D 1~ ~ 1871q 70 ~15 ~ ~5R ~33 7~331~ Me Bran IRIS 7~°lQ T
09OI771UJ. DUCT ~~Q ~ 7.;~°117~ AIMS! 711ql7n ~~ ,°1rT 01E1~ F7~A1~
(performance aPProach)J al H!2a7~ 7,4~Q r~D=7Al~(engineering approach)
Q1 70$ 13~ T(°ll2 ~°1. PI ~r~34 7l~_(Previous history). Al a, AID
71T71T °~T9 lT fir) e o1 °IO~Al ~7117= 01771 ~57. 7334~3 ~ Butt T OVA7I
~1~°1r~ ~71~7 71~ ~~!~ 71~A`I=Q Time, In Q~71~ 0~7~1 it. =71.
$]A&~ 7~ am r 77~71~7~0;~ A874~ ~11 7090 7>l~-Q °~°e°l ~70
T ~ VA ~
q~ Idol 7R~71~ ~~ me Idol ~A]1~ 70$, ~~D7~160~74 71~qlA1
~ 17,;!~ o8AA~71L: T70~ T Olga. 8,~, 7e~71~1 71~_ ~ 1 1- e ~
70a ~ CAN at. ~ 7e~ °~ }~43¢ Em di7.1 art 71 In 7e~7.18~A4 0 e Quip Laos
~71 $|o8Al~ Z)~c7~ ~7,]~ ~T2°1 Ire, of ~ 71~DA1 _I ol*7,(7t ah
71 ~32t 7;e31718~] Me —°A ~ r 7~ In 71 ugly—Ad em ~t373 U~ Itch 7~r~ 7
Q aim SO 7,joir4 3~8~7.1. fQlAt 71~71 ~ ~ ~ ~747~ ~ 7Ali=UAlqRA1 S^188
<1) ~ ,:1YdAl~ Phil ~ ;C~13 Q13 71~ ~ I+— 3~.~°~ a~.3,aq.., R71~ r~§'~lif`U(AWRs1, old} r.=91~1!C
7§ d(PHS Po]icy)~ 91 'Ydeob~ to .°~. 4.' ~ 4V ~ ^1 dilly raft, ~ r~e,3A1~7qq~4, ~~ ~ f 838
~ ^~97~ =3= Felon ~~)
16
OCR for page 3
OCR for page 4
,,?~4 ~~159Z A~°~1 jam Elm
,8~ ~r~5'ql ~;~ ~;~°1~ ~=j301~ ~0~ ~~70w 70oR0t ~~ 7~=' 3 °1
*~ °~71 A8'. 840~ +~11=7~54 ~~ ~ ~~ ^~71~ NT709° ~7
o£3_71°R ~~ BRIM *~ °107go) At, M~(IACUC)7F - ~~
~°) If. °l~ql BR~£7~1 °~ °~°R ohm £o~ 7~£o~ Cot 7F
-oR7.1~ ~~ °A7R~ ~~°~ ~7R~ ~~°1°t ~~
71~^le Ad~94~~ o~:jLol °18~ 7~°11~ 7A~171D~. o~ql~1 :ttzl~= 7F
~~ } *709I knoll Brake ~04~T OR ii7$§ age best Atgon
;itt~ mall (Guide for the Care and Use of Agricultural Anirnals in
Agricultural Research and Teaching, 1988), De ~ 7179~ol Wool 1! 7101
~70~7J°II~1 71~91 Al$~1~3+ ttel°11 (tear ~11~ 7~1~71 I ~ 1T711
tI~(Midwest Plan Service)°l ~7~ Bell +~ ~70 1!I' - (Structures and
Environment Handbook. 1987)s ~ ~4~ ~71q T(~1'1)~T~°1~ ~34418491
~ 0 ~7i the 71lE7~mE1 off< idea (L)
4. tl.7~7~ been (Nontraditional Species)
^8~ Won ;~ 01.~ 77.] ,°~~ £o~q If| ~7*51 Mao OR—I
'beams. In Sol, Isle Ins ~OnAlD~ 7~0 - I 7 7~ 327001 ril7,
~ ~ ~ o ~°11 74 ~ 74 0 ~7 °1 ol: ~ '7, of ~ who' Ad e ~0~] Q1 Mao ~ C-71 ~ T
-hi- ORBIT ~feQ7~ O^tT|!, Olin eO-eDeeO| O~~T~70On ~~ In
88~°11 ~~ 74~7aO,I z o,3~ +°R°) Id. old desk ~7~ 7A71 C ~°'i '7 Begs ma
sol 1jOol~71 Arson be 7~1~AlOnAle 721 He £o~o| 77~88 Al.$~Ury~ ~llT7a
on ~11 to O~-AI e and. 71. °e T 3ti'8471(tee°1 D1780 ~1~* $1 ~ 71 DO
71~(^e~£o;~7~7 ILAR, 0 £0~7Al34~7AtQ1 - Plan 7 §~ T YAW T~£
Al DJ 0J£7-4 ~~Q1. A}~°l| ~~ `_ ~ ~7 ~ °~ o~l ^1 ^~3 e ~~oll7jl£ 7~ {God.
°ts!1 £ollil1!0 °~ 41~7~te 7n-~7~ Ae837R~ i~1 ~ i~tt7a (invasive: ~°11
if 777g phi 7i71' 81~: O737~lE T) ~e~D7.17A17} T Dig OJ*~ If D4 ~ 71~
1 '}~71~ ~.7(]ACUC)o71 401= 7~ - Of If. OCTET 7~0D4r!0 D 771°r] OF
7~ ~7~0nA1 Old ~8oO1 ~~ o£~011~ 74°rj7'~ 717J~ °~ ~AJAl-7e T~7F ~
e71°ll i~oRAl£ ~~(]ACUC)°§ ~°0'~~. 7~77O1 ~7~ 7 0~ °~ ~~
lD 1~ ~ 1 D. OFT. In A - He batons ~§ D Knoll ~~ D1~79 Up
(U.S. Government Principles for the Utilization and Care of Vertebrate
Animals Used in Testing. Research, and Training, TO D)J ~ ~ 7-1^DA1(T~
A rum o#Aa D In o£~J D4 r71~ o T~J 4~)7t Q - Me OJ~77
In chow ~r4
18
OCR for page 5
Ova
6. JH~ (Overview)
OF BORE OF ~7 ~7R ~ of °'~3t ~ 7.lil~l~ Blot ~70~ ~ o1
R71-71 OR 5;~oFql $1il~53~ "Fmi;1 ORE ~Q7F I Aft" ~ ~1 170FoR~i ~1 4~
71 ~zti~o1 7l~isl5Yl+ *7~,F D| snot'= ~° AIR 27ciqR~1 ~1Y81~L, *8R~7a ~ old
OFFS ^1~ ~to~71 ~ 7~0J 0`F7,4$|xa~ OR loads °~o~01l:t ~ 7
Fd71~° 7~7a~ 30Z>!il~ ~il°R ~~R~Cliq.
~ 7R70a-~° 4 7R21 ~ot34 4 OR ~~°e~ ;1°~. OR lions 7 71~ 70
,4°~1°R IRAQ r~T°lA1 ~,F93, tt=A~ ~891 7rF~ MA }47~qR n7'A~—~63,
A1~F f93,iS47= ~E1 A—GINA 77~733ZE ;ilY, 770y o~7l$,3AoqR CRUD bridal (teR 71
ITCH ~ Bomb= ~°.1T~Y391~(National Research Council)91 ~ inlay 37~1
(NRC, °J~R=)~ ~ °AS - ,3 MA. *8R~F~* CITED MA AM ABLY ~ 011 Y
Isaac.
OR 270lQ ~ 7'~7'Roi3~ Iraq r^'L=ol T71~ ~70, aD~tt=1 AIDE ~ ~==F~=l~ ~
~ ~ OF A~= 7RO~F~;~ °1~1 7R 43,~A~UY. 71 ICY, *7884 r4 Sum;: C~TAA~
i1R SAFE T~847~0~! Bust C~CcF +91APZI Sol C C-~T°3~R ~913 TOYS In.
oll~cF9l~ 93.~7A 71il ~~ 71~ r4 o`le,FAlqR (tisJ 7.1~ a I
HI 470F° ~FC17= AIM, 71~r73, 07~F31 71~21iDQ ~~F21 ~Q~ ~t71, T~TgQa $3
;J 0 71 ~~ (H~.T.~.C) A| ~11 rJ Al he 77~71 ~ \37~ OR He ~03 C'
~ 7R 70Yt91 Tam +~ CRT ~°1~;1~
TV; AM TARU=~ ~2R~1 i3,~91 iLs7~Al~ +~o~oD3 To BE ~e~Ft4
;! 73 - a ~ a o~Q,3 7R7R~,l an. T_ C ~ ~91 ~C1~ A}§q1 ~;74
of UNDO 7tAlo3~0~3~ Jim De Era| tog MEL Ti7-80R ~3 We ~3. T At, Fed
stilt $3~ 01~70AT91 9 ~~l(U.S. Government Principles for the Utilization
and Care of Vertebrate Animals Used in Testing, Research, and Training,
IRAC 1985), all If o~$|Aa~(PHS)°] ~o~l~A° f~°l~
19
OCR for page 6
- ~ ~~ ~~ ~1~'
~7~
CFR (Code of Federal Regulations). 1985. Title 9 (Animals and Animal
Products), Subchapter A (Animal Welfare) Washington, D.C.: Office of
the Federal Register.
Consortium for Developing a Guide for the Care and Use of Agricultural
Animals in Agricultural Research and Teaching. 1988. Guide for the Care
and Use of Agricultural Animals in Agricultural Research and Teaching.
Champaign, III.: Consortium for Developing a Guide for the Care and Use
of Agricultural Animals in Agricultural Research and Teaching.
IRAC (Interagency Research Animal Committee). 1985. U.S. Government
Principles for Utilization and Care of Vertebrate Animals Used in Testing,
Research, and Training. Federal Register. May 20, 1985. Washington, D,C.:
Office of Science and Technology Policy.
Leader, R. W.,and D. Stark. 1987. The importance of animals in biomedical
research. PersPect. Biol. Med. 30(4):470-485.
Midwest Plan Service. 1987. Structures and Environment Handbook. 11th ed.
rev. Ames: Midwest Plan Service. Iowa State University.
NRC (National Research Council'. 1977. The Future of Animals. Cells, Models,
and Systems in Research, Development, Education, and Testing.
Proceedings of a Symposium of the institute of Laboratory Animal
Resources. Washington. D.C.: National Academy of Sciences. 341 PP.
NRC (National Research Council). in Press. Occupational Health and SafetY in
the Care and Use of Research Animals. A report of the institute of
Laboratory Animal Resources Committee on Occupational Safety and
Health in Research Animal Facilities. Washington. D.C.: National Academy
Press.
PUS (Public Health Service). 1996. Public Health Service Policy on Humane
Care and Use of Laboratorv Animals. Washington, D.C.: U.S. Department
of Health and Human Services, 28PP. [PL 99-158.Health Research
Extension Act, 1985)
Stricklin, W. R.,and J. A. Mench. 1944. Oversight of the use of agricultural
animals in university teaching and research. ILAR News 36(13:9-14.
Stricklin, W. R., D. Purcell, and J. A. Mench. 1990. Farm animals in agricultural
and biomedical research in the well-being of agricultural animals in
biomedical and agricultural research. PP. 1-4 in Agricultural Animals in
Research, Proceedings from a SCAW-sPonsored conference, September
6-7, 1990. Washington. D.C.: Scientist s Center for Animal Welfare.
Tillman. P.1994. Integrating agricultural and biomedical research Policies:
Conflicts and opportunities. ILAR News 36(2):29-35.
20
Representative terms from entire chapter:
agricultural research
