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Rights & Permissions Free PDF Access Free Resources Sign in to download PDF book and chapters Display this book on your site! Related Titles Catalyzing Inquiry at the Interface of Computing and Biology Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients) Other Related Titles (Sackler NAS Colloquium) Frontiers of Bioinformatics: Unsolved Problems and Challenges (2005) Proceedings of the National Academy of Sciences (PNAS) Web Search Builder Use this book's key terms to search within this book, across our collection, or across the Web. Skim This Chapter Skim this chapter and use this chapter's key terms to search within this book. Reference Finder Paste in your own text to find books that relate to your topic. Page 1   E-mail  Facebook  Digg  Stumble  Twitter More The following HTML text is provided to enhance online readability. Many aspects of typography translate only awkwardly to HTML. Please use the page image as the authoritative form to ensure accuracy. FRONTIERS OF BIOINFORMATICS: UNSOLVED PROBLEMS AND CHALLENGES October 15-17, 2004 Beckman Center of the National Academies 100 Academy Drive, Auditorium Irvine, California Organized by Samuel Karlin, David Eisenberg and Russ Altman PROGRAM Friday, October 15 7:45 pm Buses Depart Hyatt Newporter for Beckman Center 8:00-10:00 pm Registration, Welcome Reception, and Poster Session 10:00 pm Buses Depart Beckman Center for Hyatt Newporter Saturday, October 16 7:15 am and 7:45 am Buses Depart Hyatt Newporter for Beckman Center 7:30 am Breakfast Opening Comments 8:30 am Samuel Karlin (Stanford University) Session I: Informatics of the Human Genome (8:35 am – 12:10 pm) Chair Samuel Karlin (Stanford University) 8:35 am George Miklos (Secure Genetics Pty Limited and Human Genetic Signatures Pty Limited), Clinical Challenges for Bioinformatics 9:20 am Mark Gerstein (Yale University), Human Genome Annotation 10:05 am Break 10:35 am David Haussler (University of California, Santa Cruz), Using Evolution to Explore the Human Genome 11:20 am Pavel Pevzner (University of California, San Diego), Transforming Men into Mice (and into Cats, Dogs, Cows, Rats, Chimpanzees, etc.): Evolutionary Lessons from Mammalian Sequencing and Comparative Mapping Projects 12:10 pm Lunch Session II: Motifs and Genomics (1:30–3:00 pm) Chair Russ Altman (Stanford University) 1:30 pm Peer Bork (European Molecular Biology Laboratory), Genome Evolution and Protein Networks 2:15 pm Phil Green (Howard Hughes Medical Institute and University of Washington), Signal and Noise in Genomic Sequences 3:00 pm Break Page 1 Front Matter (R1-R4) Program (1-2) Presentation Abstracts (3-24) Poster Session (25-26) Poster Abstracts (27-46) Participant Roster (47-54)

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Frontiers of Bioinformatics: Unsolved Problems and Challenges FRONTIERS OF BIOINFORMATICS: UNSOLVED PROBLEMS AND CHALLENGES October 15-17, 2004 Beckman Center of the National Academies 100 Academy Drive, Auditorium Irvine, California Organized by Samuel Karlin, David Eisenberg and Russ Altman PROGRAM Friday, October 15 7:45 pm Buses Depart Hyatt Newporter for Beckman Center 8:00-10:00 pm Registration, Welcome Reception, and Poster Session 10:00 pm Buses Depart Beckman Center for Hyatt Newporter Saturday, October 16 7:15 am and 7:45 am Buses Depart Hyatt Newporter for Beckman Center 7:30 am Breakfast Opening Comments 8:30 am Samuel Karlin (Stanford University) Session I: Informatics of the Human Genome (8:35 am – 12:10 pm) Chair Samuel Karlin (Stanford University) 8:35 am George Miklos (Secure Genetics Pty Limited and Human Genetic Signatures Pty Limited), Clinical Challenges for Bioinformatics 9:20 am Mark Gerstein (Yale University), Human Genome Annotation 10:05 am Break 10:35 am David Haussler (University of California, Santa Cruz), Using Evolution to Explore the Human Genome 11:20 am Pavel Pevzner (University of California, San Diego), Transforming Men into Mice (and into Cats, Dogs, Cows, Rats, Chimpanzees, etc.): Evolutionary Lessons from Mammalian Sequencing and Comparative Mapping Projects 12:10 pm Lunch Session II: Motifs and Genomics (1:30–3:00 pm) Chair Russ Altman (Stanford University) 1:30 pm Peer Bork (European Molecular Biology Laboratory), Genome Evolution and Protein Networks 2:15 pm Phil Green (Howard Hughes Medical Institute and University of Washington), Signal and Noise in Genomic Sequences 3:00 pm Break

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Frontiers of Bioinformatics: Unsolved Problems and Challenges Session III: Protein-Protein Interactions (3:30–6:00 pm) Chair Valerie Daggett (University of Washington) 3:30 pm David Eisenberg (University of California, Los Angeles), Protein Interactions 4:15 pm Hanah Margalit (The Hebrew University of Jerusalem), From Cellular Networks to Molecular Interactions and Back 5:00 pm Shoshana Wodak (Hospital for Sick Children), Protein-Protein Interactions: The Challenge of Predicting Specificity 6:15 Reception and Poster Session 8:00 Dinner Russell F. Doolittle (University of California, San Diego), Regarding Irreducible Complexities, Introduced by David Eisenberg (University of California, Los Angeles) 10:30 Buses Depart Beckman Center for Hyatt Newporter Sunday, October 17 7:15 am and 7:45 am Buses Depart Hyatt Newporter for Beckman Center 7:30 am Breakfast Session IV: Regulation with RNA and Aspects of Splicing (8:30–10:45 am) Chair David Eisenberg (University of California, Los Angeles) 8:30 am Sean Eddy (Washington University, St. Louis), The Modern RNA World: Computational Screens for Noncoding RNA Genes 9:15 am Christopher Burge (Massachusetts Instittue of Technology), Toward an RNA Splicing Code 10:00 am Christopher Lee (University of California, Los Angeles), Discovering Evolutionary Mechanisms from Multiple Metrics of Molecular Evolution 10:45 am Break Session V: Protein Structure (11:00 am – 12:30 pm) Chair George Miklos (Secure Genetics Pty Limited and Human Genetic Signatures Pty Limited) 11:00 am Helen Berman (Rutgers University), Probing the PDB 11:45 am Michael Levitt (Stanford University), Structural Alignment and Classification of all Known Protein Structure 12:30 pm Lunch Session VI: Transcription and Translation in Eukaryotic Genomes (1:30–4:45 pm) Chair George Miklos (Secure Genetics Pty Limited and Human Genetic Signatures Pty Limited) 1:30 pm Volker Brendel (Iowa State University), Comparative Plant Genomics: Evaluation of the Model Genome Concept 2:15 pm Terry Gaasterland (Rockefeller University and University of California, San Diego/SIO), Lessons from the Arabadopsis Genome: Decoding Evidence for Novel Transcription 3:00 pm Break 3:15 pm Russ Altman (Stanford University), Building Genotype Phenotype Data Resources 4:00 pm Samuel Karlin (Stanford University), Highly Expressed Genes Based on Codon Usage Biases in Archaeal and Eukaryotic Genomes 5:00 pm Buses Depart Beckman Center for Hyatt Newporter and Orange County Airport

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