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Review of the Department of Energy's Genomics: GTL Program (2006)

Chapter: Appendix B Presentations to the Committee

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Suggested Citation:"Appendix B Presentations to the Committee." National Research Council. 2006. Review of the Department of Energy's Genomics: GTL Program. Washington, DC: The National Academies Press. doi: 10.17226/11581.
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Appendix B
Presentations to the Committee

Keck Center of the National Academies

September 25, 2005


Ari Patrinos, U.S. Department of Energy, Office of Biological and Environmental Research; Michael Strayer, U.S. Department of Energy, Office of Advanced Scientific Computing Research

Overview of Genomics: GTL program


James Fredrickson, Pacific Northwest National Laboratory

Progress and potential of Genomics: GTL program and challenges it faces


George Church, Harvard Medical School

Role of Genomics: GTL in genome engineering and synthetic biology


Derek Lovley, University of Massachusetts, Amherst

Role of Genomics: GTL in bioremediation and biofuel research


George Pierce, Georgia State University

Role of Genomics: GTL in bioremediation research


Craig Venter, J. Craig Venter Institute

Role of Genomics: GTL in carbon-sequestration research

Suggested Citation:"Appendix B Presentations to the Committee." National Research Council. 2006. Review of the Department of Energy's Genomics: GTL Program. Washington, DC: The National Academies Press. doi: 10.17226/11581.
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Elbert Branscomb, Lawrence Livermore National Laboratory

Role of Genomics: GTL in achieving DOE’s mission—national-laboratory perspective


Michael Himmel, National Renewable Energy Laboratory (NREL)

Relation of Genomics: GTL to NREL programs


Eric Eisenstadt, The Institute for Genomic Research

Role of Genomics: GTL in advancing genomic research—nonprofit institution’s perspective


Joel Parriott, Executive Office of the President, Office of Management and Budget (OMB); Michael Salamon, Executive Office of the President, Office of Science and Technology Policy (OSTP)

Genomics: GTL—OMB and OSTP’s perspective


September 26, 2005


James Tiedje, Michigan State University

Role of Genomics: GTL in environmental research


Mark Guyer, National Institutes of Health, National Human Genome Research Institute (NHGRI)

Relation of Genomics: GTL to NHGRI’s programs


Joanne Tornow, National Science Foundation (NSF), Directorate for Biological Sciences

Relation of Genomics: GTL to NSF’s genomics programs


Ann Lichens-Park, U.S. Department of Agriculture (USDA), Cooperative State Research, Education, and Extension Service

Relation of Genomics: GTL to USDA genomics programs


Martin Godbout, Genome Canada

Genome Canada—successes, lessons learned, and relation to Genomics: GTL


Dawn Field, Oxford Center for Ecology and Hydrology

Environmental Genomics Thematic Programme Data Centre—successes, lessons learned, and relation to Genomics: GTL

Suggested Citation:"Appendix B Presentations to the Committee." National Research Council. 2006. Review of the Department of Energy's Genomics: GTL Program. Washington, DC: The National Academies Press. doi: 10.17226/11581.
×
Page 83
Suggested Citation:"Appendix B Presentations to the Committee." National Research Council. 2006. Review of the Department of Energy's Genomics: GTL Program. Washington, DC: The National Academies Press. doi: 10.17226/11581.
×
Page 84
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The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL’s research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE’s goals. However, the DOE’s current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE’s mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.

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