to an evaluation of the impact of the Research Program Grants was not systematically collected.

This is the third in a series of reports that document the activities of the Markey Trust. The previously published, Bridging the Bed-Bench Gap: Contributions of the Markey Trust, examines the General Organizational Grants program, while The Markey Scholars Conference Proceedings summarizes presentations and abstracts from the 2002 Markey Scholars Conference held as part of the National Academies evaluation. Both reports are available through the National Academies Press. Additional reports will assess the Markey Scholars and Visiting Fellows programs and publish the proceedings of a workshop on evaluation practices in philanthropic and public organizations that support biomedical scientists.

Just as each of the Markey programs varied in terms of goals and focus, so did the committee’s approach to assessment and evaluation. The Markey Scholars program was evaluated prospectively and is amenable to greater methodological rigor than this assessment of Research Program Grants or the previously published examination of the General Organizational Grants. This report relies on expert judgments and on the information gathered in site visits. It is organized into several sections and a set of appendixes, beginning with a history of the Markey Trust and the Markey grant programs. It continues with a discussion of the methodological issues related to evaluating these programs as a whole and the Research Program Grants in particular, and it briefly describes each of the 92 Research Program Grants funded by the Markey Trust. It concludes with potential lessons for funding organizations or individual philanthropists with analogous interests in supporting biomedical research. The appendixes summarize the site visits and telephone interviews with principal investigators conducted by the committee, expert consultants, and NRC staff.

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