Reference

Study Design

Description

Study Group (n)

Comparison Group (n)a

Reports from AFHS Reviewed in Update 2004

Akhtar et al., 2004

Cohort

Follow-up to Ketchum et al. (1999), comparing cancer incidence among Ranch Hands with Vietnam veterans who served in Southeast Asia but did not spray herbicides and with US national cancer rates

1,189 net Ranch Hands for external analysis; 1,009 net Ranch Hands for internal analysis

1,776 net comparison subjects for external analysis; 1,429 net comparison subjects for internal analysis

Barrett et al., 2003

Cohort

Serum TCDD measurement and psychological functioning among Ranch Hand veterans

1,109

1,493

Michalek et al., 2003

Cohort

Correlation for TCDD elimination and Ranch Hands with diabetes

343

No comparison group

Pavuk et al., 2003

Cohort

Study to examine the relationship between serum TCDD and thyroid function in Ranch Hand veterans

1,009

1,429

Barrett et al., 2001

Cohort

Based on tests of cognitive functioning in 1982 and dioxin concentrations measured in 1987 and 1992, analyzed association between serum dioxin levels and cognitive functioning

937 Ranch Hand

1,052 Ranch Hand comparisons

Michalek et al., 2001a

Cohort

Based on physical examination through 1992 and medical records reviewed through March 1993, association between serum dioxin levels and hepatic abnormality

1,109 Ranch Hand

1,493 Ranch Hand comparisons

Michalek et al., 2001b

Cohort

Based on physical examination in 1982, 1985, 1987, 1992, and 1997 and medical records through 1997, association between serum dioxin and peripheral neuropathy

761 Ranch Hand

1,086 Ranch Hand comparisons

Michalek et al., 2001c

Cohort

Based on physical examination in 1982, 1985, 1987, and 1992 and medical records through 1997, association between serum dioxin and hematologic function

953 Ranch Hand

1,280 Ranch Hand comparisons



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