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Toxicity Testing in the 21st Century: A Vision and a Strategy (2007)
Board on Environmental Studies and Toxicology (BEST)
Institute for Laboratory Animal Research (ILAR)

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. "3 Components of the Vision." Toxicity Testing in the 21st Century: A Vision and a Strategy. Washington, DC: The National Academies Press, 2007.

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Toxicity Testing in the 21st Century: A Vision and a Strategy

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Timsit, Y.E. and M. Negishi. 2006. CAR and PXR: The xenobiotic-sensing receptors. Steroids 72(3):231-246.

Van Wuytswinkel, O., V. Reiser, M. Siderius, M.C. Kelders, G. Ammerer, H. Ruis, and W.H. Mager. 2000. Response of Saccharomyces cerevisiae to sever osmotic stress: Evidence for a novel activation mechanism of the HOG MAP kinase pathway. Mol. Microbiol. 37(2):382-397.

Volarath, P., H. Wang, H. Fu, and R. Harrison. 2004. Knowledge-based algorithms for chemical structure and property analysis. Conf. Proc. IEEE Eng. Med. Biol. Soc. 4:3011-3014.

Wang, X.J., J.D. Hayes, and C.R. Wolf. 2006. Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of nrf2 by cancer chemotherapeutic agents. Cancer Res. 66(22):10983-10994.

Waxman, D.J. 1999. P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR. Arch. Biochem. Biophys. 369(1):11-23.

Weis, B.K., D. Balshaw, J.R. Barr, D. Brown, M. Ellisman, P. Lioy, G. Omenn, J.D. Potter, M.T. Smith, L. Sohn, W.A. Suk, S. Sumner, J. Swenberg, D.R. Walt, S. Watkins, C. Thompson, and S.H. Wilson. 2005. Personalized exposure assessment: Promising approaches for human environmental health research. Environ. Health Perspect. 113(7):840-848.

Westerheide, S.D., and R.I. Morimoto. 2005. Heat shock response modulators as therapeutic tools for diseases of protein conformation. J. Biol. Chem. 280(39):33097-33100.

Woodruff, T.J., D.A. Axelrad, A.D. Kyle, O. Nweke, G.G. Miller, and B.J. Hurley. 2004. Trends in environmentally related childhood illnesses. Pediatrics 113(Suppl. 4):1133-1140.

Zhang, D.D. 2006. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev. 38(4):769-789.

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