In 2007 the Institute of Medicine established the Roundtable on Translating Genomic-Based Research for Health. The purpose of the Roundtable is to foster dialogue and discussion that will advance the field of genomics and improve the translation of research findings to health care, public health, and health policy. As a first step in examining issues of translation of genomic innovations, the Roundtable decided to hold a workshop to gather information on three questions below. Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions:

  1. Are there different pathways by which new scientific findings move from the research setting into health care?

  2. If so, what are the implications of those different pathways for genomics?

  3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care?

The December 4, 2007, workshop was moderated by Wylie Burke, chair of the Roundtable, and consisted of panel presentations in four areas: the process of translation of innovations, practical incentives and barriers to translation, translation of genomic technology at the clinical level, and opportunities and constraints for translation both within the United States and globally. A discussion period followed each panel. At the conclusion of the meeting Burke offered a summary of the day’s presentations. While various types of genomic innovation were discussed, a number of presentations focused primarily on genomic testing technologies. The complete agenda can be found in Appendix A, and biographical sketches of the speakers are in Appendix B.

The following report summarizes speaker presentations and discussions. Any conclusions reported should not be construed as reflecting a group consensus, rather they are the statements and opinions of presenters and participants.



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