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Suggested Citation:"Appendix A Committee Members and Staff." Institute of Medicine. 2008. Assessment of the Role of Intermittent Preventive Treatment for Malaria in Infants: Letter Report. Washington, DC: The National Academies Press. doi: 10.17226/12180.
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Appendix A Committee Members and Staff COMMITTEE ON THE PERSPECTIVES ON THE ROLE OF INTERMITTENT PREVENTIVE TREATMENT FOR MALARIA IN INFANTS MYRON M. LEVINE (Chair), University of Maryland School of Medicine OLUSEGUN OLUSINA AKINYINKA, University of Ibadan JOEL BREMAN, Fogarty International Center, National Institutes of Health NEAL HALSEY, Johns Hopkins University Bloomberg School of Public Health CARL KENDALL, Tulane University School of Public Health and Tropical Medicine MIRIAM K. LAUFER, University of Maryland School of Medicine COLONEL ALAN J. MAGILL, Walter Reed Army Institute of Research WILLIAM J. MOSS, Johns Hopkins University Bloomberg School of Public Health CHRISTOPHER V. PLOWE, University of Maryland School of Medicine CECILIA ABIMBOLA WILLIAMS, Partnership for Transforming Health Systems/ United Kingdom Department for International Development’s Nigeria Office VIRGINIA WISEMAN, London School of Hygiene and Tropical Medicine JANET WITTES, Statistics Collaborative CHARLOTTE MUHEKI ZIKUSOOKA, HealthNet Consult IOM Staff PATRICK KELLEY, Director, Board on Global Health KIMBERLY SCOTT, Study Director IJEOMA EMENANJO, Research Associate MILA C. GONZÁLEZ, Research Assistant (from November 2007) ALLISON BRANTLEY, Senior Program Assistant (through March 2008) AUDRA BLANCHFIELD, Intern (from September to December 2007) MICHELE KELLEY, Consultant Editor FLORENCE POILLON, Editor JULIE WILTSHIRE, Financial Associate 65

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Intermittent Preventive Treatment for Malaria in Infants (IPTi) is a new strategy which aims to combine the short-term protection of chemoprophylaxis with the long-term protection of naturally-acquired immunity to reduce morbidity from malaria infections during infancy. The Bill and Melinda Gates Foundation requested that the Institute of Medicine (IOM) conduct an independent assessment of the IPTi efficacy studies using sulfadoxine-pyrimethamine (IPTi-SP) that have been previously conducted by the IPTi Consortium. The IOM convened a committee to evaluate the evidence concerning IPTi-SP, which included addressing issues related to its utility and safety, as well as program management aspects of IPTi. The resulting letter report contains the findings, conclusions, and recommendations of the IOM committee. Overall, the committee found that the evidence presented makes IPTi-SP a promising public health strategy to diminish the morbidity from malaria infections, especially for the incidence of clinical malaria, among infants at high risk who reside in areas of high- or moderate-intensity transmission and is worthy of continued investment. The committee also cautioned that during large-scale implementation problems such as drug supply and logistics; monitoring and resistance; and community acceptance and reaction to IPTi-SP could arise. To maximize the greatest public health impact, the committee advised that these issues would best be addressed in an appropriate local context.

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