Ocular and throat irritation and slight dyspnea

Inhalation of PG; 1 min; mean concentration = 309 mg/m³ (~ 96 ppm)

Human, Wieslander et al. 2001

LOAEL = 96 pp

32

—

—

—

—

—

Nasal hemorrhage and ocular discharge

Inhalation of PG; 6 h/d, 5 d/wk; 0.16, 1.01, 2.18 mg/L (160, 1,000, 2,200 mg/m³ or 50, 313, 688 ppm)

Sprague-Dawley rat, Suber et al. 1989

NOAEL for 1 wk = 50 ppm; ten Berge method used

—

17

—

—

—

—

Nasal hemorrhage and ocular discharge

Inhalation of PG; 6 h/d, 5 d/wk; 0.16, 1.01, 2.18 mg/L (160, 1,000, 2,200 mg/m³ or 50, 313, 688 ppm)

Sprague-Dawley rat, Suber et al. 1989

NOAEL for 1 wk = 50 ppm

—

—

9

—

—

—

Nasal hemorrhage and ocular discharge

Inhalation of PG; 6 h/d, 5 d/wk; 0.16, 1.01, 2.18 mg/L (160, 1,000, 2,200 mg/m³ or 50, 313, 688 ppm)

Sprague-Dawley rat, Suber et al. 1989

LOAEL for 2 wk = 50 ppm

—

—

—

3

—

—

Thickening of respiratory epithelium with increased goblet cells and their mucin

Inhalation of PG; 6 h/d, 5 d/wk; 0.16, 1.01, 2.18 mg/L (160, 1,000, 2,200 mg/m³ or 50, 313, 688 ppm)

Sprague-Dawley rat, Suber et al. 1989

NOAEL = 50 ppm

—

—

—

—

1.5

1.5

SMACs

32

17

9

3

1.5

1.5