Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.
OCR for page 82
Venture Funding and the NIH SBIR Program
Appendix D
Venture-funded Firms: Data from Hoover’s Small Business Database and VentureSource
Company
Venture Capital (Thousands of Dollars)
Rounds
Last Round Date
Advanced Tissue Sciences, Inc.
90,578.0
3
11/2/2001
Albion Instruments
8,968.0
7
1/1/1990
Ambion, Inc.
10,500.0
1
5/1/2003
Applied Immune Sciences, Inc.
44,060.1
11
1/1/1991
Applied Molecular Evolution, Inc.
32,350.0
6
6/1/2000
Aronex Pharmaceuticals, Inc.
9,496.0
3
3/2/1999
Aviron (FKA: Vector Pharmaceuticals, Inc.)
87,340.1
4
11/1/2000
Argus Software, Inc.
3,815.9
4
7/30/1999
Aurora Biosciences Corporation
18,720.0
3
12/15/1996
AcryMed, Inc.
3,500.0
4
3/1/2003
Alexion Pharmaceuticals, Inc.
5,800.0
2
12/23/1994
Automatix, Inc.
21,850.0
7
12/1/1987
Aastrom Biosciences, Inc.
36,384.9
8
10/30/2002
ABIOMED, Inc.
35,800.0
1
3/27/2007
Adolor Corporation
137,483.0
7
5/31/2001
Alkermes, Inc.
12,384.3
5
10/1/1992
Amylin Pharmaceuticals, Inc.
84,200.0
9
9/20/2002
ARIAD Pharmaceuticals, Inc.
56,075.0
3
5/20/2003
Aradigm Corporation
139,454.0
9
3/7/2003
Altea Therapeutics
54,546.9
4
6/15/2007
Amedica Corporation
44,569.0
4
4/27/2007
Amnis Corporation
18,750.0
3
3/27/2006
Ancile Pharmaceuticals, Inc.
30,365.0
6
10/27/2002
OCR for page 83
Venture Funding and the NIH SBIR Program
First Round Date
Status
Ticker Symbol
Last Known Date
Annual Revenue (Millions of Dollars)
Number of Employees
Profit/Loss
4/1/1996
Out of business
2003
6/1/1986
Sold
2000
5/1/2003
Sold
2006
13.6
11/1/1984
Sold
1995
3/1/1990
Sold
10.2
7/1/1991
Sold
2001
6/1/1992
Sold
1/1/1995
Foreign
3/7/1996
Foreign
4/1/1994
n/a
11/12/1993
NASDAQ
ALXN
1.6
241
(131.5)
1/1/1980
n/a
8/18/1989
NASDAQ
ASTM
0.7
(17.6)
3/27/2007
NASDAQ
AMMD
50.7
324
11/1/1994
NASDAQ
ADLR
15.9
179
(69.7)
10/1/1987
NASDAQ
alks
240.0
830
9.9
11/1/1987
NASDAQ
AMLN
510.9
1,550
(218.9)
2/1/1991
NASDAQ
ARIA
0.9
108
(61.9)
10/16/1992
OTC
ARDM
4.8
103
(13.0)
11/21/2002
private
1/28/2004
private
failed IPO
2007
0.1
33
(6.3)
2/28/2000
private
3.5
37
11/4/1998
private
3.2
30
OCR for page 84
Venture Funding and the NIH SBIR Program
Company
Venture Capital (Thousands of Dollars)
Rounds
Last Round Date
Artecel Sciences, Inc.
4,135.2
2
5/29/2002
Atherotech, Inc.
21,399.9
4
1/31/2005
Avocet Medical, Inc.
36,801.0
3
7/1/2001
BioCryst Pharmaceuticals, Inc.
39,964.9
3
9/30/2007
BioMarin Pharmaceutical, Inc.
53,000.0
2
5/16/2001
BIOQUAL, Inc. (FKA: Diagnon Corporation)
1,351.0
2
5/1/1983
Biosearch, Inc.
1,800.0
2
12/1/1983
Biosym Technologies, Inc.
5,168.0
3
4/1/1992
BioTransplant, Inc.
9,561.0
3
6/30/2001
Cambridge Neuroscience, Inc. (FKA: Synax, Inc.)
35,879.0
9
6/21/1997
Cell Based Delivery, Inc.
11,175.0
2
5/7/2002
Centaur Pharmaceuticals, Inc.
63,451.0
7
11/2/2001
Cephalon, Inc.
40,037.8
8
2/25/1999
Chektec Corporation
846.0
3
4/1/1993
Clarus Medical LLC (Medilase, Inc.)
27,548.9
12
5/1/1997
Clontech Laboratories, Inc.
28,836.0
2
7/1/1998
CoCensys, Inc.
24,071.0
9
1/7/1997
Cognetix, Inc.
19,010.0
2
6/1/2006
CompuCyte Corporation
18,700.0
3
8/1/1999
Conductus, Inc.
45,699.9
6
3/27/2002
Control Delivery Systems, Inc. (AKA: CDS, Inc.)
34,500.0
1
8/22/2000
COR Therapeutics, Inc.
20,652.0
6
1/1/1998
Corixa Corporation
157,581.1
6
6/10/2003
Cortex Pharmaceuticals, Inc.
9,100.0
2
7/1/1989
Creative BioMolecules, Inc.
23,284.0
18
7/1/1995
Cryolife, Inc.
3,057.0
3
6/1/1988
Cryopharm Corporation
30,346.0
10
1/1/1994
Cubist Pharmaceuticals, Inc.
36,283.0
5
9/23/1998
CuraGen Corporation
26,790.0
2
9/1/1999
CytoLogix Corporation
46,850.0
5
5/29/2002
Cytomation, Inc.
14,293.0
2
6/8/2001
Cytyc Corporation (FKA: Generitech Corporation)
35,154.9
4
5/1/1995
Dharmacon Research, Inc.
5,700.0
1
8/23/2002
Digirad Corporation (FKA: Aurora Technologies)
75,320.0
9
4/24/2002
DiscoveRx Corporation, Ltd.
28,406.0
5
2/20/2007
Discovery Laboratories, Inc.
13,211.0
2
6/20/2003
Displaytech, Inc.
70,225.1
5
3/12/2006
Edenspace Systems Corporation
5,250.0
1
4/23/2007
EKOS Corporation
85,900.4
8
6/27/2007
Endocyte, Inc.
60,700.2
4
3/23/2007
Epicyte Pharmaceutical, Inc.
22,200.0
4
4/16/2001
EpiGenesis Pharmaceuticals, Inc.
35,956.2
4
3/7/2007
Epoch Biosciences (FKA:MicroProbe Corporation)
30,030.2
13
7/1/1993
OCR for page 85
Venture Funding and the NIH SBIR Program
First Round Date
Status
Ticker Symbol
Last Known Date
Annual Revenue (Millions of Dollars)
Number of Employees
Profit/Loss
11/29/2000
private
0.1
1
3/31/1999
private
10/1/1996
private
8/1/1992
NASDAQ
6.2
52
(43.6)
1/1/1998
NASDAQ
84.2
314
(28.5)
7/1/1981
private
19.4
150
4/1/1983
private
4.6
65
10/1/1986
Sold
10/1/1995
Out of business
2003
1/1/1986
Sold
3/7/2002
Out of business
12/1/1992
Out of business
2002
10/1/1987
NASDAQ
CEPH
18,641.1
2,895
144.8
12/1/1988
Outof business
1/6/1989
private
0.2
3
7/1/1997
private
17.0
175
2/1/1989
Sold
8/1/2001
Out of business
4/1/1996
private
6.7
28
9/1/1987
Sold
8/22/2000
Sold
2005
17.2
26
3/16/1988
Sold
2002
12/2/1994
Sold
2005
5/1/1988
AMEX
COR
1.2
26
(16.2)
5/1/1982
NASDAQ
CRIS
16.7
68
(8.8)
1/1/1986
NYSE
CRY
81.3
363
0.4
1/1/1988
private
2.5
25
9/1/1992
NASDAQ
CBST
194.8
410
(0.4)
3/1/1997
NASDAQ
CRGN
39.6
666
(59.8)
1/1/1997
private
5/1/1997
Sold
1/1/1987
Sold
2006
608.0
1,500
139.5
8/23/2002
private
10.1
120
5/30/1995
NASDAQ
DRAD
71.9
601
(6.3)
2/1/1999
private
3.3
40
11/5/2002
NASDAQ
0.0
160
(46.3)
4/11/2000
IPO
2002
3.2
47
4/23/2007
private
0.7
10
10/1/1996
private
9.5
99
7/1/2001
private
3.3
40
7/1/1996
Sold
2004
10/1/1997
private
3/1/1986
Sold
2004
OCR for page 86
Venture Funding and the NIH SBIR Program
Company
Venture Capital (Thousands of Dollars)
Rounds
Last Round Date
EraGen Biosciences, Inc. (FKA: Sulfonics, Inc.)
32,647.0
3
3/15/2007
Exogene Corporation
7,115.1
5
7/1/1993
Fluorous Technologies, Inc. (AKA: FTI)
3,650.0
2
5/23/2003
Genaera Corporation (FKA: Magainin Pharmaceuticals)
18,106.0
5
10/1/1998
Genaissance Pharmaceuticals, Inc.
75,749.9
4
11/4/2004
Genelabs Technologies, Inc.
34,949.4
8
6/29/2006
GeneMedicine, Inc.
8,900.0
2
7/13/1994
Genetic Therapy, Inc.
13,989.0
8
7/1/1994
GenPharm International, Inc.
18,989.1
8
2/29/2000
Geron Corporation
42,074.8
5
1/1/1996
Gilead Sciences, Inc.
32,060.0
6
8/1/1992
Gliatech, Inc.
32,596.1
7
6/1/1995
Hauser Chemical Research, Inc.
1,893.0
3
12/7/1990
Hawaii Biotech, Inc.
16,500.0
5
12/26/2006
Houston Biotechnology, Inc.
3,240.0
2
5/1/1986
Hypres, Inc.
39,841.0
20
12/31/2002
Icagen, Inc.
96,700.7
7
2/1/2007
Illumigen Biosciences, Inc.
7,950.0
8
7/6/2007
Illumina, Inc.
36,567.0
2
11/1/1999
Immtech Pharmaceuticals, Inc. (FKA: Immtech International)
2,509.0
3
2/14/1994
ImmuLogic Pharmaceutical Corporation
29,844.0
5
2/22/1993
Immunicon Corporation
106,800.4
7
6/29/2005
ImmunoGen, Inc.
21,934.0
7
1/1/1989
Immusol, Inc.
23,500.0
2
9/24/2003
IntraTherapeutics, Inc. (FKA: Cardia Catheter Company)
32,224.2
8
3/31/2000
Invitrogen Corporation
15,000.0
1
6/20/1997
Iomai Corporation
80,570.0
9
10/25/2006
Irvine Sensors Corporation
2,650.0
3
6/10/2003
Isis Pharmaceuticals
17,490.0
6
8/11/1994
Isolab, Inc.
2,744.0
2
6/28/1990
ISTO Technologies, Inc.
25,725.0
5
8/3/2007
Kurzweil Applied Intelligence, Inc.
26,122.1
13
1/1/1993
Large Scale Biology Corp. (FKA: Biosource Genetics Corp)
11,675.1
6
3/1/1998
Laser Diagnostic Technology, Inc.
13,310.9
5
11/30/2001
Laserscope
24,045.4
8
9/1/1987
LeukoSite, Inc.
32,613.1
8
7/1/1998
LifeSpan BioSciences, Inc.
19,000.0
1
4/17/2001
Linguagen Corporation
20,212.0
4
5/23/2006
Lucent Medical Systems, Inc.
6,700.0
2
9/25/1998
Lynx Therapeutics, Inc.
72,200.4
5
9/25/2003
Markwell Medical Institute, Inc.
882.0
5
5/1/1987
MediChem Research Inc.
35,000.0
1
6/28/1999
Medinox, Inc.
21,199.8
2
1/8/2002
OCR for page 87
Venture Funding and the NIH SBIR Program
First Round Date
Status
Ticker Symbol
Last Known Date
Annual Revenue (Millions of Dollars)
Number of Employees
Profit/Loss
10/6/2005
private
10/1/1988
Sold
1996
6/20/2000
private
2.0
15
3/1/1988
NASDAQ
GENR
0.9
46
(21.2)
8/1/1998
Sold
2005
10/1/1984
NASDAQ
GNLB
11.2
66
(8.7)
10/1/1992
private
14.9
110
8/1/1988
private
1.0
15
2/29/2000
Sold
7/10/1992
NASDAQ
GERN
3.3
90
(31.4)
8/1/1987
NASDAQ
GILD
3,026.1
2,525
(1,190.0)
7/1/1988
Sold
2000
4/1/1988
Out of business
6/7/2002
private
5.1
65
10/1/1985
Sold
7/1/1983
private
8.0
33
10/1/1995
NASDAQ
ICGN
8.4
72
(24.8)
5/1/2000
private
1.5
10
11/30/1998
NASDAQ
ILMN
184.5
277
40.0
12/21/1992
AMEX
IMM
4.3
27
(11.3)
5/1/1987
Out of business
2002
7/1/1988
NASDAQ
IMMC
8.7
107
(24.0)
6/1/1981
NASDAQ
IMGN
38.2
192
(19.0)
6/1/2001
Sold
10/7/1991
Sold
2001
6/20/1997
NASDAQ
1,263.5
4,835
(191.0)
1/1/1998
NASDAQ
IOMI
1.5
66
(31.8)
10/1/1997
NASDAQ
IRSN
30.8
166
(8.5)
2/1/1989
NASDAQ
ISIS
24.5
258
(45.9)
5/1/1987
Foreign
3/1/2000
private
1.6
24
5/1/1984
private
12/1/1987
private
0.8
20
1/1/1994
Foreign
3/1/1983
Sold
2006
9/1/1994
Sold
1999
4/17/2001
private
3.3
40
12/30/2003
private
7/1/1997
private
0.5
7
2/15/1994
Sold
2007
6/1/1981
Out of business
6/28/1999
private
6/15/1999
private
OCR for page 88
Venture Funding and the NIH SBIR Program
Company
Venture Capital (Thousands of Dollars)
Rounds
Last Round Date
MediSpectra, Inc.
58,970.0
8
7/21/2006
Meridian Instruments, Inc.
3,557.0
4
10/1/1993
Message Pharmaceuticals, Inc.
11,142.5
8
4/14/2004
MIICRO, Inc.
6,840.0
4
9/26/2001
MIDI
2.0
8,250
5/3/2004
Moberg Medical, Inc. (AKA: Moberg Research, Inc.)
5,473.8
6
4/1/1997
Molecular Dynamics, Inc.
22,717.0
7
7/1/1994
Myogen, Inc.
191,452.8
6
10/13/2004
Nanosphere, Inc.
80,130.1
5
5/16/2006
NeoGenesis, Inc.
22,999.9
1
6/21/2001
Nereus Pharmaceuticals, Inc.
127,345.6
8
8/9/2007
NeuroControl Corporation
22,800.0
9
1/4/2001
Neurocrine Biosciences, Inc.
21,499.9
6
5/23/1996
Neuron Therapeutics, Inc. (FKA: ICTUS Pharmaceuticals)
28,717.0
4
12/7/2001
NimbleGen Systems, Inc.
73,250.5
8
1/2/2007
Nimbus Medical, Inc.
9,635.1
3
7/1/1986
Octagen Corporation
4,800.0
2
3/6/2000
Ontogen
24,945.0
5
10/13/2000
Onyx Pharmaceuticals, Inc.
70,200.2
6
5/9/2002
Organ Recovery Systems
13,999.8
1
7/29/2004
Orquest, Inc.
42,814.8
5
10/16/2001
Palatin Technologies
45,700.0
3
1/30/2004
Panacos Pharmaceuticals, Inc.
26,550.0
3
6/28/2007
Perlan Therapeutics, Inc.
5,227.0
3
12/27/2001
Pharmacopeia Drug Discovery, Inc.
8,472.0
1
8/11/2005
PharmaSonics, Inc.
22,700.0
4
6/30/2002
Pharmavene, Inc.
13,044.0
3
6/1/1996
PHT Corporation (AKA: Personal Health Technologies Corp.)
48,250.2
6
10/18/2004
Phylos, Inc.
25,100.0
1
11/30/2000
Physical Optics Corporation
3,337.0
4
8/1/1990
Physical Sciences, Inc.
492.0
2
7/1/1995
Premier Laser Systems, Inc
6,145.0
4
1/1/1997
Progenics Pharmaceuticals, Inc.
21,448.0
2
12/27/2005
Promega Corporation
5,250.0
4
5/27/1993
PRP, Inc.
384.0
2
1/1/1996
Proteome, Inc.
8,100.0
1
12/1/1999
Quantum Dot Corporation (AKA: Q Dot)
39,150.0
3
8/10/2005
Quantum Magnetics, Inc.
3,800.0
3
7/1/1997
Replidyne, Inc.
126,500.1
6
8/17/2005
Repligen Corporation
12,234.0
3
5/1/1985
RiboGene, Inc. (FKA: Transgene)
48,233.2
15
2/1/1997
Sangamo Biosciences
16,950.0
3
12/31/2001
Sangart, Inc.
50,353.0
2
4/4/2007
OCR for page 89
Venture Funding and the NIH SBIR Program
First Round Date
Status
Ticker Symbol
Last Known Date
Annual Revenue (Millions of Dollars)
Number of Employees
Profit/Loss
6/1/1996
private
1.6
21
5/1/1983
Sold
1/1/1998
Out of business
2004
10/31/1997
private
1.6
20
5/19/2005
private
1.3
25
1/1/1992
private
9/1/1987
Sold
1998
10/5/1998
Sold
2006
1/25/2000
NASDAQ
NSPH
1.1
50
113.0
1/9/2001
Sold
2005
7/29/1998
private
9.3
29
3/3/1994
private
9/25/1992
NASDAQ
NBIX
39.2
588
(107.2)
10/1/1998
private
9/1/2000
Sold
3/1/1988
Sold
1996
4/1/1998
private
5/19/1992
Out of business
2003
4/24/1992
NASDAQ
0.3
125
(92.7)
1/20/2003
private
2.4
27
6/8/1994
Sold
2003
11/1/1996
AMEX
PTN
14.4
85
(27.8)
11/4/2000
NASDAQ
PANC
0.3
32
(38.1)
6/4/1999
private
1.2
14
8/11/2005
NASDAQ
PCOP
16.9
150
(27.8)
2/1/1997
Out of business
4/1/1993
Sold
11/3/1999
private
8.4
80
11/30/2000
private
1.7
18
8/1/1987
private
30.0
150
5/9/1995
private
12.4
150
4/1/1994
Out of business
12/1/1995
NASDAQ
PGNX
69.9
149
(21.6)
10/1/1982
private
175.0
850
4/1/1996
private
6.8
130
12/1/1999
private
1/1/1999
Sold
2005
10/15/1995
Out of business
2/21/2002
NASDAQ
RDYN
16.0
85
(29.3)
11/1/1981
NASDAQ
RGEN
14.1
45
(0.9)
1/1/1990
Sold
1999
6/1/1996
NASDAQ
SGMO
7.9
62
(17.9)
10/31/2004
private
7.3
35
OCR for page 90
Venture Funding and the NIH SBIR Program
Company
Venture Capital (Thousands of Dollars)
Rounds
Last Round Date
Scios Nova, Inc. (F.K.A Scios Inc) California Biotechnology)
5,425.0
1
6/1/1982
Secretech
800.0
2
10/1/1990
Selective Genetics, Inc. (FKA: Prizm Pharmaceuticals, Inc.)
56,867.0
14
12/1/2003
Sepracor, Inc.
16,892.0
8
2/22/1993
Signal Pharmaceuticals, Inc.
44,543.7
10
12/1/1999
Spire Corporation
3,750.0
3
1/1/1987
Stratagene Cloning Systems
1,873.0
2
12/31/1992
Structural Bioinformatics, Inc.
46,371.7
4
3/22/2000
Sunesis Pharmaceuticals, Inc. (FKA: Mosaic Pharmaceutical)
163,338.1
8
5/30/2007
Synaptic Pharmaceutical Corporation (FKA:Neurogenetic Corp)
89,772.2
7
9/5/2001
T Cell Sciences, Inc.
3,634.0
3
10/1/1989
Targeted Genetics Corporation
46,450.0
4
6/28/2007
TechniScan Medical Systems, Inc.
6,400.0
1
2/5/2007
Tegic Communications, Inc. (AKA:T9 Text Input)
15,000.0
2
5/4/1999
Telefactor Corporation
450.0
3
12/31/1998
Telios Pharmaceuticals, Inc.
30,530.0
7
1/1/1993
Third Wave Technologies, Inc.
78,064.2
5
7/26/2000
TraceDetect, Inc.
1,600.0
2
11/17/2003
TransMolecular, Inc.
42,364.3
4
2/20/2004
Trimeris, Inc. (FKA: SL-1 Pharmaceuticals, Inc.)
38,283.0
6
9/1/1999
United Biomedical, Inc.
9,000.0
1
7/1/1997
UroCor, Inc. (FKA: CytoDiagnostics, Inc.)
16,600.1
5
7/1/1995
VaxGen, Inc.
29,449.0
2
3/1/1997
Vertex Pharmaceuticals, Inc.
13,538.0
5
10/1/1996
VueSonix Sensors
4,600.0
3
7/30/2004
Xeotron Corporation
9,000.0
1
5/1/2001
Xeyex Corporation
3,267.0
2
6/30/1999
Zynaxis, Inc.(FKA: Zynaxis Cell Science/PKH Labs)
37,581.0
8
1/1/1995
Martek Biosciences Corporation
35,167.1
8
1/1/1986
Vestar, Inc.
34,509.1
15
7/1/1981
Vical, Inc.
17,850.0
7
6/1/1987
NOTE: Hoover’s data reflect current data available through Hoover’s Small Business Database as of September 2007.
SOURCES: Data on VC investments are from VentureSource; data on current and historical firms status are from Hoover’s Small Business Database (<http://www.hoovers.com>).
OCR for page 91
Venture Funding and the NIH SBIR Program
First Round Date
Status
Ticker Symbol
Last Known Date
Annual Revenue (Millions of Dollars)
Number of Employees
Profit/Loss
6/1/1982
Sold
9/1/1989
Out of business
6/12/1992
private
1/1/1984
NASDAQ
SEPR
1,196.5
228
184.6
1/1/1993
private
48.5
134
11/1/1979
NASDAQ
SPIR
20.1
118
(8.1)
4/1/1987
Sold
11/1/1996
Sold
2/17/1998
NASDAQ
SNSS
13.7
138
1/1/1987
Sold
4/1/1985
Out of business
6/1/1992
NASDAQ
TGEN
9.9
95
(34.0)
2/5/2007
private
1/22/1998
Sold
12/31/1997
Sold
2000
1/1/1986
Sold
6/30/1995
NASDAQ
TWTI
28.0
154
(18.9)
3/15/2002
private
1.4
12
9/30/1997
private
1.2
18
2/12/1993
NASDAQ
TRMS
37.0
90
7.4
7/1/1997
private
13.8
285
7/1/1987
Sold
4/10/1996
private
1/1/1989
NASDAQ
TRTX
216.4
320
(206.9)
6/9/2000
private
5/1/2001
Sold
2004
1/1/1997
Out of business
6/1/1988
Out of business
2/1/2005
NASDAQ
MATK
270.0
582
14.9
7/1/1993
Out of business
2000
3/10/1993
NASDAQ
VICL
14.7
155
(23.1)