BOX 7-3

Examples of Conflict of Interest Policy Descriptions Excerpted from Summaries in the National Guideline Clearinghouse

Example A


Not stated. [This is the most common entry for the period from 1999 to 2006.]

Example B


To assure the integrity of the Advisory Committee on Immunization Practices (ACIP), the U.S. Department of Health and Human Services has taken steps to assure that there is technical compliance with ethics statutes and regulations regarding financial conflicts of interest. Concerns regarding the potential for the appearance of a conflict are addressed, or avoided altogether, through both pre-and postappointment considerations. Individuals with particular vaccine-related interests will not be considered for appointment to the committee. Potential nominees are screened for conflicts of interest, and if any are found, they are asked to divest or forgo certain vaccine-related activities. In addition, at the beginning of each ACIP meeting, each member is asked to declare his or her conflicts. Members with conflicts are not permitted to vote if a conflict involves the vaccine or biologic being voted upon. [NGC, 2009g; see also ACIP, 2007]

Example C


The American Academy of Neurology (AAN) is committed to producing independent, critical and truthful clinical practice guidelines (CPGs). Significant efforts are made to minimize the potential for conflicts of interest to influence the recommendations of this CPG. To the extent possible, the AAN keeps separate those who have a financial stake in the success or failure of the products appraised in the CPGs and the developers of the guidelines. Conflict of interest forms were

American College of Chest Physicians, whose policies are summarized in Box 7-4.

Effectiveness of Policies

The committee identified no evaluations of the impact of conflict of interest policies on the content of guidelines or other outcomes. The review by Boyd and Bero (2006) also found no rigorous assessments of conflict of interest policies for guideline development and no evaluations of different strategies for implementing or enforcing them.

The National Academies of Sciences, Engineering, and Medicine
500 Fifth St. N.W. | Washington, D.C. 20001

Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement