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Suggested Citation:"Abbreviations." National Research Council. 2009. Sixteenth Interim Report of the Committee on Acute Exposure Guideline Levels. Washington, DC: The National Academies Press. doi: 10.17226/12761.
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Page 38
Suggested Citation:"Abbreviations." National Research Council. 2009. Sixteenth Interim Report of the Committee on Acute Exposure Guideline Levels. Washington, DC: The National Academies Press. doi: 10.17226/12761.
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Page 39

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Abbreviations ACGIH American Conference of Governmental Industrial Hygienists, a member-based organization for advancement of occupational and environmental health. AEGL acute exposure guideline level AEGL-1 The airborne concentration (expressed as ppm [parts per million] or mg/m3 [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic nonsensory effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure. AEGL-2 The airborne concentration (expressed as ppm or mg/m3) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape. AEGL-3 The airborne concentration (expressed as ppm or mg/m3) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life- threatening adverse health effects or death. ATSDR Agency for Toxic Substances and Disease Registry, a federal public health agency of the U.S. Department of Health and Human Services BrF5 bromine pentafluoride BrF3 bromine trifluoride CEEL community emergency exposure level ChE Cholinesterase ClF5 chlorine pentafluoride ClF3 chlorine trifuoride CNS central nervous system COHb carboxyhemoglobin EHS extremely hazardous substance EPA U.S. Environmental Protection Agency ERPG emergency response planning guideline GB nerve agent GB h hour HBr hydrogen bromide HCl hydrogen chloride HF hydrogen fluoride HI hydrogen iodide HSDB Hazardous Substances Data Bank H2Se hydrogen selenide H2SeO3 monohydrated selenium dioxide IDLH immediately dangerous to life and health LC01 concentration of a substance that is lethal to 1% of test organisms in a given time 38

LC50 concentration of a substance that is lethal to 50% of test organisms in a given time LD50 dose of a substance that is lethal to 50% of test organisms in a given time LOA level of distinct odor awareness LOAEL lowest-observed-adverse-effect level MAC maximaal aanvaarde concentratie (maximum accepted concentration) MAK maximale argeitsplatzkonzentration (maximum workplace concentration) min minute NAC National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances NIOSH National Institute for Occupational Safety and Health NO2 nitrogen dioxide NOAEL no-observed-adverse-effect level NOEL no-observed-effect level NRC National Research Council NTP National Toxicology Program ORNL Oak Ridge National Laboratory PBPK physiologically based pharmacokinetic POD point of departure ppm parts per million RBC red blood cell RD50 concentration of a substance that reduced the respiratory rate of test organisms by 50% REL reference exposure level SO2 sulfur dioxide SeF6 selenium hexafluoride SeO selenium oxide SFEMG Single Fiber Electromyography SOP standard operating procedure STEL short-term exposure limit TLV Threshold Limit Value TMB trimethylbenzene TPA 12-O-tetra-decanoly-phorbol-13-acetate TSD technical support document UF uncertainty factor WEEL workplace environmental exposure limit 39

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Extremely hazardous substances (EHSs) can be released accidentally as a result of chemical spills, industrial explosions, and other accidents, or intentionally through terrorist activities. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental or intentional releases.

To help understand the risk involved with EHSs, the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances developed Acute Exposure Guideline Levels (AEGLs) for approximately 200 EHSs.

The present volume is the sixteenth interim report evaluating the AEGLs. It summarizes conclusions and recommendations for improving NAC's AEGL documents for 26 chemicals. The report also summarizes the committee's conclusions and recommendations for improving the Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances published in 2001.

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