Vaccination of adults

Persons at risk for infection by sexual exposure

  • Sex partners of HbsAg-positive persons.

  • Sexually active persons who are not in a long-term, mutually monogamous relationship (for example, persons with more than one sex partner during the previous 6 months).

  • Persons seeking evaluation or treatment for a sexually transmitted disease.

  • Men who have sex with men.

Persons at risk for infection by percutaneous or mucosal exposure to blood

  • Current or recent injection-drug users.

  • Household contacts of HBsAg-positive persons.

  • Residents and staff of facilities for developmentally disabled persons.

  • Health-care and public-safety workers who have a reasonably anticipated risk of exposure to blood or blood-contaminated body fluids.

  • Persons with end-stage renal disease, including predialysis, hemodialysis, peritoneal-dialysis, and home-dialysis patients.

  • Incarcerated persons.


  • International travelers to regions that have high or intermediate levels (HBsAg prevalence of at least 2%) of endemic HBV infection.

  • Persons who have chronic liver disease.

  • Persons who have HIV infection.

  • All other persons who are seeking protection from HBV infection.

Abbreviations: ACIP, Advisory Committee on Immunization Practices; HBsAg, hepatitis B surface antigen; HBIG, hepatitis B immune globulin.

SOURCE: Adapted from Mast et al., 2005, 2006.

tis B vaccine are being missed or delayed, which the committee believes is due to the lack of a delivery-room policy for hepatitis B vaccination. Missing or delaying the birth dose for infants born to HBsAg-positive women substantially increases the risk that they will develop chronic hepatitis B. To reduce the incidence of perinatal HBV infections, the committee offers the following recommendation:

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