1. Serologic testing. Serologic testing is laboratory testing of blood specimens for biomarker confirmation of HBV or HCV infection.

Risk-Factor Screening

Hepatitis B Risk-Factor Screening CDC has identified risk factors for becoming infected or chronically infected with HBV (see Box 5-4). As discussed in Chapter 3, improved provider awareness about risk factors is critical for ensuring that people at risk for chronic HBV infection are identified and that those at risk for becoming infected with HBV are vaccinated. Providers should review patients’ backgrounds (for example, country of birth) and discuss relevant behaviors to determine what services they need.

Figure 5-1 illustrates the pathway of services and care for people depending on their risk factors identified. People who have HIV infection or other sexually transmitted infections, men who have sex with men, injection-drug users (IDUs), and institutionalized and incarcerated persons

BOX 5-4

Summary of CDC At-Risk Populations for Hepatitis B Virus Infection

  • Persons born in geographic regions that have HBsAg prevalence of at least 2%

  • Infants born to infected mothers

  • Household contacts of persons who have chronic HBV infection

  • Sex partners of infected persons

  • Injection-drug users

  • Sexually active persons who are not in long-term, mutually monogamous relationships (for example, more than one sex partner during previous 6 months)

  • Men who have sex with men

  • Health-care and public-safety workers at risk for occupational exposure to blood or blood-contaminated body fluids

  • Residents and staff of facilities for developmentally disabled persons

  • Persons who have chronic liver disease

  • Hemodialysis patients

  • Travelers to countries that have intermediate or high prevalence of HBV infection

SOURCE: Mast et al., 2005, 2006.

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