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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making (2010)
Food and Nutrition Board (FNB)

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making

Index

A

ACE-Obesity. See Assessing Cost-Effectiveness in Obesity Study

Adaptability, 122, 168, 295

defined, 209

Adoption, 141, 145

Advocacy groups, 201

African Americans. See Ethnicity

Alternative study designs to randomized experiments, 172181, 277296.

See also Research designs

how well do alternative designs work?, 180181

American Indians. See Ethnicity

Applicability. See Generalizability

Appraisals

defining, 57, 227

Archival studies

as sources of evidence, 101

Arkansas framework for combating childhood and adolescent obesity, with national recommendations for action, 97

Assembling evidence and informing decisions, 89, 133157

guidance for assembling the evidence, 135144

knowledge integration, 154155

the L.E.A.D. framework for obesity prevention decision making, 134

a template for summarizing the evidence, 144, 146154

tools for assembling evidence, 145146

Assessing Cost-Effectiveness in Obesity Study, 98

Assessment, 9394, 97, 144.

See also Evaluating evidence

Audiences. See Target audiences

Average causal effect, 177

B

Body mass index (BMI), 23

changes in the distribution of, 24

lowering, 36, 3940

screening in schools, 75

Building a resource base

recommendations concerning, 1213, 203204

C

Caloric balance. See Energy-balance equation

Campbell Collaboration, 123

Campbell perspective, 174177, 279, 281282, 284, 288

design elements used in constructing quasi-experiments, 178179

Canadian Task Force on the Periodic Health Examination, 121

Cancer. See Diseases related to obesity

Cardiovascular disease. See Diseases related to obesity

Case-comparison studies. See Case-control studies

Case-control studies

as sources of evidence, 100102

Case study research

as sources of evidence, 103104, 109

Causal pathways, 63, 93

Causality, 27, 174180.

See also Average causal effect;

Mapping

perspectives on, 174180

CBO. See Congressional Budget Office

CBPR. See Community-based participatory research

CDC. See U.S. Centers for Disease Control and Prevention

Certainty.

See also Internal validity;

Level of certainty

Clarity, 8, 144.

See also Assembling evidence and informing decisions

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Index A ACE-Obesity. See Assessing Cost-Effectiveness in Obesity Study Adaptability, 122, 168, 295 defined, 209 Adoption, 141, 145 Advocacy groups, 201 African Americans. See Ethnicity Alternative study designs to randomized experiments, 172–181, 277–296. See also Research designs how well do alternative designs work?, 180–181 American Indians. See Ethnicity Applicability. See Generalizability Appraisals defining, 57, 227 Archival studies as sources of evidence, 101 Arkansas framework for combating childhood and adolescent obesity, with national recommendations for action, 97 Assembling evidence and informing decisions, 8–9, 133–157 guidance for assembling the evidence, 135–144 knowledge integration, 154–155 the L.E.A.D. framework for obesity prevention decision making, 134 a template for summarizing the evidence, 144, 146–154 tools for assembling evidence, 145–146 Assessing Cost-Effectiveness in Obesity Study, 98 Assessment, 93–94, 97, 144. See also Evaluating evidence Audiences. See Target audiences Average causal effect, 177 B Body mass index (BMI), 23 changes in the distribution of, 24 lowering, 36, 39–40 screening in schools, 75 Building a resource base recommendations concerning, 12–13, 203–204 C Caloric balance. See Energy-balance equation Campbell Collaboration, 123 Campbell perspective, 174–177, 279, 281–282, 284, 288 design elements used in constructing quasi-experiments, 178–179 Canadian Task Force on the Periodic Health Examination, 121 Cancer. See Diseases related to obesity Cardiovascular disease. See Diseases related to obesity Case-comparison studies. See Case-control studies Case-control studies as sources of evidence, 100–102 Case study research as sources of evidence, 103–104, 109 Causal pathways, 63, 93 Causality, 27, 174–180. See also Average causal effect; Mapping perspectives on, 174–180 CBO. See Congressional Budget Office CBPR. See Community-based participatory research CDC. See U.S. Centers for Disease Control and Prevention Certainty. See also Internal validity; Level of certainty Clarity, 8, 144. See also Assembling evidence and informing decisions

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Cluster randomization design, 172–173 Cochrane Collaboration of Systematic Reviews, 59, 121, 138, 225 COCOMO. See Common Community Measures for Obesity Prevention Cohort studies, 215 as sources of evidence, 100–101 Committee on an Evidence Framework for Obesity Prevention Decision Making, 2, 17, 19–22, 197 Common Community Measures for Obesity Prevention, 110, 224 Communicating and disseminating the framework, 188–193 channels, 190–191 implementation and monitoring, 192–193 messages and materials, 192 objectives, 188 partnerships, 191–192 recommendations concerning, 14–15, 205–206 target audiences, 188–190 Communities and neighborhoods approaches designed to foster changes in, 27, 43–44 Community assessment (needs assessment), 91–93, 135 Community-based participatory research, 295 Community Preventive Services Task Force, 123 Comorbidities. See Diseases related to obesity Comparative effectiveness research, 118–120 as areas of evidence needed, 93–94 Comparative experiments as areas of evidence needed, 93–94 Comprehensive approach for preventing and addressing childhood obesity, 29 Conceptual frameworks for evidence selection lack of, 57–58 Conclusions, of the L.E.A.D. framework for obesity prevention decision making, 198–201 Congressional Budget Office, 162 Consensus views. See Expert knowledge Consolidated Standards of Reporting Trials, 121 Content analysis, 61 as sources of evidence, 104–108 Context, 5, 138 evaluating, 7–8, 115–123 influencing interventions, 63–64 from a systems perspective/rationale, 71–87, 151–152 Continuous quality assessment, of ongoing programs, 171 Coordinated Approach to Child Health program, 49 Cost/benefit analysis as areas of evidence needed, 95–96 Cost-effectiveness analysis as areas of evidence needed, 95–96 Cost-feasibility analysis as areas of evidence needed, 95 Cost-minimization analysis as areas of evidence needed, 95 Cost-utility analysis as areas of evidence needed, 95 Cross-cutting factors, 39–40 Cross-sectional studies as sources of evidence, 100–102 D Decision makers, 3, 27, 201 See also Target audiences defined, 211 and intermediaries, 22, 188–189 Decision making comprehensive approach for preventing and addressing childhood obesity, 29 context of, 138 evidence-informed, 2 obesity prevention, and evidence needs, 26–30 physical, social, and emotional health consequences of obesity in adults, children, and youth, 27 relative risk of health problems associated with obesity in adults, 27 Defining the problem, 71–87. See also Systems perspective application and future directions, 83–84 relation to the L.E.A.D. framework, 83 understanding a systems approach, 72–74 uses of systems thinking, approaches, mapping, and modeling, 75–83 Delphi Method, 126–127 Design elements that strengthen causal inferences in observational studies, 285 used in constructing quasi-experiments in Campbell’s perspective, 178–179 Desired outcomes, 194. See also Evaluating and refining the L.E.A.D. framework Diabetes. See Diseases related to obesity Dietary Guidelines for Americans, 40, 46 Diseases related to obesity, 21, 26–27, 36–37 Disparities, 38–39 Dissemination of the L.E.A.D. framework, 10, 188–193 “Downstream” approaches, 39 E EBM. See Evidence-based medicine EBPH. See Evidence-based public health EBPP. See Evidence-based public policy Ecological models, 28–29, 41–42, 72 Economic cost analysis, 288–290

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making as sources of evidence, 101 Editors. See Journals and journal editors Effectiveness research, 98, 123, 133–142, 149. See also Generalizability; Impact as areas of evidence needed, 93–94 as sources of evidence, 106, 108–109 Effects, size of, 106, Efficacy. See Level of certainty Energy-balance equation, 6, 18, 22–23, 37–38 Ethnicity, 24–25, 96, 173 Ethnographic studies, 103 Evaluability assessment of emerging innovations, 170–171, 200 Evaluating and refining the L.E.A.D. framework, 193–195 adoption and utilization of, 193 data collection methods and opportunities, 194–195 desired outcomes, 194 integration of evaluation findings into the L.E.A.D. framework, 195 objectives, 193–194 recommendations concerning, 14–15, 205–206 Evaluating evidence, 7–8, 115–131, 224 approaches to, 62 criteria for assessing quality of evidence, 125–126 existing approaches to evaluating evidence, 121, 123–124 generalizability and contextual considerations, 120–122 identification of appropriate outcomes, 118–120 the L.E.A.D. framework for obesity prevention decision making, 116 a proposed approach to evaluating the quality of scientific evidence, 124–128 a user’s perspective, 117–118 when scientific evidence is not a perfect fit—trade-offs to consider, 128 Evaluating interventions. See also Assembling evidence and informing decisions effectiveness, 137–139 impact, 141–142 Evaluation framework for childhood obesity prevention policies and interventions, 39 for government efforts to support capacity development for preventing childhood obesity, 119 for industry efforts to develop low-calorie and nutrient-dense beverages and promote their consumption by children and youth, 120 Evidence. See Assembling evidence and informing decisions; Evaluating evidence; Gaps in evidence; Locating evidence; Opportunities to generate evidence; Sources of evidence; Status of the current evidence base Evidence-based decision making, 2, 28 in public health, 1, 60–61 Evidence-based medicine, 2, 59–60, 171 Evidence-based public health, 60–61 Evidence-based public policy, 61 Evidence-related projects, 223–226 evaluation, 224 guidelines, 223 measures, 224 systematic reviews, 224–225 uses of, 226 Evidence synthesis, 105–108, 125, 136, 139, 213 meta-analyses, 106–107 mixed-method evidence synthesis, 107–108 as sources of evidence, 105–108 syntheses of qualitative research, 107 systematic reviews, 105–106 types of evidence synthesis methods and examples of their uses, 106 Evidence tables, 149–151. See also Assembling evidence and informing decisions template for, 150 Existing evidence needs, 161–163 considerations for increasing evaluation of obesity prevention initiatives, 162 selected recommendations for research in childhood obesity prevention, 163 Existing tools for assembling evidence, 144–146. See also Assembling evidence and informing decisions Experimental and quasi-experimental studies, 101, 103, 125 types of experimental and quasi-experimental evidence and examples of their uses, 103 Experimental designs, 60, 175 Expert knowledge, 123, 126 as sources of evidence, 109–110 types of expert knowledge and examples of their uses, 110 External validity. See Generalizability F FCC. See Federal Communications Commission Federal Communications Commission, 281, 283 Fidelity, 142–143 Focus groups, 65, 103 Foresight Tackling Obesities: Future Choices Project, 80–83 Form components, 143. See also Generalizability Foundations, 12–13, 190, 203–204. See also Target audiences

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Framework. See also L.E.A.D. framework conclusions regarding, 198–201 defining, 21–22 need for, 3 objectives regarding, 193–194 Frequency, 92 Functional components, 143. See also Generalizability Funders. See Research funders; Resources needed G Gaps in evidence, 26–30, 56–59 ways to fill, 169–171 Gathering evidence, 110–111. See also Information sources for locating evidence Generalizability, 7–9, 58, 62, 95–96, 116–118, 143, 166, 200 and contextual considerations, 120–123 defined, 213 evaluating, 13 limitations in the way evidence is reported in scientific journals, 166–169 quality rating criteria for external validity, 122 recommendations concerning, 13–14, 204–205 Generating evidence. See Opportunities to generate evidence recommendations concerning, 13–14, 204–205 Geographic mapping, 102 Government, as an evidence source, 272 Grading of Recommendations Assessment, Development, and Evaluation, 144–145 Graph theoretic approach, 180 Grey and unpublished literature as evidence sources, 271 Guidance for assembling the evidence, 135–144. See also Assembling evidence and informing decisions existing tools for assembling evidence, 144–146 how do we implement this information for our situation?, 142–144 what specifically should we do about this problem?, 136–142 why should we do something about this problem in our situation?, 135–136 Guidelines other evidence projects, 223 H Harm, 7, 28, 83 Head Start program, 279 HEALCP. See Healthy Eating Active Living Convergence Partnership Health Canada, 145 Health communication and social marketing approaches, to obesity prevention, 44–45 Health consequences of obesity, physical, social and emotional, 27 Health disparities, 92. See also Disparities Health Forecasting, 127 Health impact assessment, 94, 127 Healthy Eating Active Living Convergence Partnership, 189, 191–192 HEALTHY study, 96 HHS. See U.S. Department of Health and Human Services High-risk populations, 163 evidence to identify, 91–93 HIV. See Human immunodeficiency virus “How” questions, 6–7, 95–96, 98–99 how do we implement this information for our situation?, 142–144, 149–150, 153–154 areas of concerns and examples of evidence needed, 95 posing “Why,” “What,” and “How” questions after a policy or program is in place, 96–98 Human immunodeficiency virus programs to prevent, 293 Hypertension. See Diseases related to obesity I Identification of appropriate outcomes, 118–120 evaluation framework for government efforts to support capacity development for preventing childhood obesity, 119 evaluation framework for industry efforts to develop low-calorie and nutrient-dense beverages and promote their consumption by children and youth, 120 Identifying and locating evidence evidence synthesis methods, 105–108 an expanded view, 89–114 experimental and quasi-experimental studies, 101, 103 expert knowledge, 109–110 gathering the evidence, 110–111 the L.E.A.D. framework for obesity prevention decision making, 90 mixed-method studies, 104–105 nonexperimental or observational studies, 100–102 parallel evidence, 108–109 potentially useful, 100–110 qualitative research, 103–104 specifying questions—an evidence typology for the L.E.A.D. framework, 91–100

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Impact of interventions, 93–94, 136–142, 149, 151–153 of the L.E.A.D. framework, 193–194 Impact evaluation (or assessment), 127 as areas of evidence needed, 93–94 Implementation, 141, 168, 192–193 of interventions, 95–96, 122, 142–144 of the L.E.A.D. framework, 192–193 Incorporating systems thinking recommendations concerning, 12, 203 Indicated interventions, 37–38, 141, 153 Information sources for locating evidence, 269–275 government, 272 Grey and unpublished literature, 271 policies and programs, 273–275 scientific literature databases, 269–270 surveys, polls, and rankings, 272 Initiative on the Study and Implementation of Systems, 78 Institute of Medicine, 18–19, 124, 135, 161, 197 Institutionalization, of an intervention or program, 122, 168. See also Quality rating criteria for external validity Integration of evaluation findings into the L.E.A.D. framework, 187, 195 of the L.E.A.D. framework into public health decision making and related research, 188, 194, 195 of relevant evidence and knowledge into systems, 154 Interdisciplinary integration, 84 Internal validity. See also Level of certainty key assumptions/threats to, and example remedies for randomized controlled trials and alternatives, 176 International Obesity Task Force, 65, 91 Interrupted time series analysis, 174, 176, 180, 277–278, 281–283 as sources of evidence, 101, 103–105 Interventions defined, 215 IOM. See Institute of Medicine IOTF. See International Obesity Task Force ISIS. See Initiative on the Study and Implementation of Systems Iterative steps, in system dynamics modeling, 79 ITS. See Interrupted time series analysis J Journals and journal editors, 11–12, 14, 15, 20, 57, 65, 110, 111, 160, 166, 190–191, 193, 200–201, 203, 205, 206, 293. See also Target audiences K Kaiser Permanente, 20, 197 Knowledge integration, 134, 154, 200 defined, 215 L L.E.A.D. framework, 5, 66–68 communication and dissemination of, 187–193 conclusions regarding, 199, 201 evaluation and refinement of, 187, 193–195 fundamental evidence concepts in, 59–65 implementing fully, 111 key assumptions guiding use of, 11, 202 and new opportunities for research, 3 for obesity prevention decision making, 67, 73 and population health problems, 55 rationale for and overview of, 55–70, 149 recommendations concerning, 14–15, 205–206 using the L.E.A.D. framework, 4–10 Level of certainty, 7, 8, 11, 59, 62, 64, 115, 118, 121, 123, 124, 127, 138, 149, 152, 161, 172, 174–176, 200, 202, 283–284, 287–288, 294. See also Internal validity key assumptions/threats to internal validity and example remedies for randomized controlled trials and alternatives, 176 Locate Evidence, Evaluate Evidence, Assemble Evidence, Inform Decisions. See L.E.A.D. framework Locating evidence, 7 information sources for, 269–275 strategies for, 89–114, 148–149 Logic models/modeling, 28, 65, 135–136, 151, 294 for obesity prevention, 39–41, 119 as sources of evidence, 103–104 Longitudinal studies, 100, 102, 118, 282, 289 as sources of evidence, 100, 102 Low-income as a risk factor for obesity, 24, 26, 163 M Maintenance, 141, 168, 187, 201, 224 assessing the extent of for an intervention, 118 as a dimension of generalizability, 52, 122 as part of RE-AIM, 144–145 Managed care programs, 45 Mapping, 84, 104, 139, 141, 146, 293–294, See also Matching, mapping, pooling, and patching defined, 215

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making of obesity causality in the United States, 79–81 systems, 12, 74, 203 the obesity “system”—a broad causal map, 81 MATCH. See Multilevel Approach to Community Health Matched cohort studies as sources of evidence, 101, 103 Matching, 139, 146, 177, 290–292, 294. See also Matching, mapping, pooling, and patching the Multilevel Approach to Community Health model used to align the source of evidence with the targets of an intervention, plan and evaluate programs, and integrate knowledge for community partnering, 292 Matching, mapping, pooling, and patching, 139, 160, 290–296 as tools for assembling evidence, 146 Measurement approaches to, 64–65 of BMI in schools, 75 Menu-labeling case study, 99 Meta-analyses, 57, 105–107, 138–139, 145, 167, 171, 180, 227 Mexican Americans. See Ethnicity Military readiness, effect of obesity on, 26 Mixed-method evidence synthesis as sources of evidence, 107–108 Mixed-method studies, 104–105, 125, as sources of evidence, 104–105 types of mixed-method evidence and examples of their uses, 104–105 Monitoring, the L.E.A.D. framework, 192–193 Multilevel, multisector obesity prevention approaches, 46–49 example of a multilevel approach—childhood obesity prevention in Texas, 47–49 multilevel, multisector approach to childhood obesity prevention in Texas, 48 need for, 46–47 Multilevel Approach to Community Health, 291–292 Multisite designs, 172–173. See also Randomized controlled trials N National Chronic Disease Directors, 190 National Collaborative on Childhood Obesity Research, 191–192 National Health and Nutrition Examination Surveys, 1, 22–24, 45, 272 National Health Examination Survey, 22 National Health Interview Survey, 105 National Institutes of Health, 45, 127, 154, 162, 165 Native Hawaiians. See Ethnicity Natural experiments, 9, 159, 163, 169, 200 defined, 216 NCCOR. See National Collaborative on Childhood Obesity Research Needs assessment, 150, 216 as areas of evidence needed, 96 New York City Department of Health, 43–44, 137 Next steps, in communicating, disseminating, evaluating and refining the L.E.A.D. framework, 10, 187–195. See also L.E.A.D. framework communicating and disseminating the framework, 188–193 communication and dissemination plan, 187 conclusions regarding, 201 evaluating and refining the framework, 193–195 evaluation and refinement plan, 187 NHANES. See National Health and Nutrition Examination Surveys NIH. See National Institutes of Health Nonequivalent control group design. See Observational studies Nonexperimental studies, 216. See also Observational studies O Obesity, 1, 23, 200, 216 diseases related to, 21, 26 and health consequences in adults, children, and youth, 27 and overweight as a societywide problem, 1, 17, 22–26 prevalence of, 18, 23–25, 44 Obesity prevention approaches, 35–54 approaches designed to foster changes in communities and neighborhoods, 43–44 approaches involving changes in organizational policies, environments, and practices, 42–43 in the broader context of other public health initiatives, 49–51 considerations for increasing evaluation of, 162 current evidence base, 9–10, 55–59, 201–202, 227–267 definitions and types of prevention, 36–39 differences from obesity treatment, 21 health communication and social marketing approaches, 44–45 interventions in health care settings, 45 lessons for obesity prevention from other public health problems, 50 logic models for obesity prevention, 39–40 multilevel, multisector obesity prevention approaches, 46–49 policy and legislative approaches, 42

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making population-based, 22 the spectrum of obesity prevention approaches, 41–49 target behaviors for, 41 types of, 37–39 in the United Kingdom, 80, 82–83 Obesity “system” a broad causal map, 81 simplified version of the United Kingdom Foresight Group’s causal loop obesity system map, 82 Objectives, of communicating, disseminating, evaluating, and refining the L.E.A.D. framework, 188, 193–194 Observational studies, 65, 100–102, 125, 139, 176, 283–287 comparison of their results with results of randomized studies, 180–181 design elements that strengthen causal inferences in observational studies, 285 as evidence sources, 100–102 types of observational evidence and examples of their uses, 102 within the evidence hierarchy, 60 Opportunities to generate evidence, 5, 9–10, 117, 159–186 alternatives to randomized experiments, 172–181 existing evidence needs, 161–183 the L.E.A.D. framework for obesity prevention decision making, 161 limitations in the way evidence is reported in scientific journals, 166–169 the need for new directions and transdisciplinary exchange, 164–166 perspectives on causal inference, 174–180 recommendations concerning, 13–14, 204–205 ways to fill the gaps in the best available evidence, 169–171 Organizational policies, environments, and practices. See also Obesity prevention approaches approaches involving changes in, 42–43 Osteoarthritis. See Diseases related to obesity Outcomes for decision making, as a dimension of external validity, 122 for evaluating obesity prevention interventions, 58–59 Overweight prevalence in the United States, 1 P Pacific Islanders. See Ethnicity Paradigm shift in thinking about obesity prevention, 17, 35 Parallel evidence, 100, 108–109, 126 as sources of evidence, 108–109 types of parallel evidence and examples of their uses, 109 PATCH. See Planned Approach to Community Health Patching, 139, 141, 146, 290, 295–296. See also Matching, mapping, pooling, and patching Planned Approach to Community Health, 295 Peer-reviewed journals. See Journals and journal editors Physical activity. See Energy-balance equation Planned Approach to Community Health, 295 Policies and programs as evidence sources, 273–275 Policy analysis as sources of evidence, 101 Policy makers. See Target audiences Policy scanning/tracking locating, 274 as sources of evidence, 127 Pooling, 139, 140, 145, 146, 290, 293–294. See also Matching, mapping, pooling, and patching Population-based interventions for obesity, 35, 37, 42 challenges of applying the traditional evidence base to, 57–59 Population health problems addressing with transdisciplinary exchange, 164–165 and the L.E.A.D. framework, 55 and a systems approach, 74 Practice-based interventions (or evidence), 14, 169, 200, 205, 294–296 Pre-/posttest designs, 175–177, 287–288 Predictive studies as sources of evidence, 101–102 Prevalence, 77, 107, 211 and economic-cost analysis study designs, 288–290 as a measure of the scope of a problem, 99, 107, 118 of obesity compared to the paucity of the knowledge base with which to inform prevention efforts, 56 of obesity in diverse populations, 18 Prevention, of obesity in adults and children, 36 definitions and types of, 36–39 Professional organizations, 190, 204. See also Target audiences Program planners, 201. See also Target audiences Program theory analysis as sources of evidence, 103–104 Propensity scoring, 286–287 Prospective studies, 215 Public health organizations, 12. See also Target audiences Public health problems—lessons for obesity prevention, strategies to address, 50 Publishers of research findings, 4, 11, 13, 14, 22, 117, 190. See also Journals and journal editors; Target audiences

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Q Qualitative research, 60, 65, 84, 103–104, 125, 137–139, 153 assessing quality of, 125–127 for evaluating evidence, 62 as sources of evidence, 100, 103–105, 107–108 synthesis of, 105, 107–108 types of qualitative evidence and examples of their uses, 104 Quality rating criteria for external validity, 122 maintenance and institutionalization, 122 outcomes for decision making, 122 program or policy implementation and adaptation, 122 reach and representativeness, 122 Quantitative data (or research), 65, 84, 125, 127, 138–139, 145, 153, 277, 279, 280–281, 295–296 Quasi-experimental studies, 60, 64, 84, 125, 138, 145, 164, 174, 178, 277, 278, 283, 287 as sources of evidence, 100–101, 103, 105–106 Questions asked by the decision maker, 99, 147–148 that guide the gathering of evidence, 6–7, 91 that need to be answered, types of, 61–62 R Randomized controlled trials, 57, 62, 116, 138–139, 176, 277, 280 alternatives to, 172–181 multisite designs, 172 prevailing preference for, 164 as sources of evidence, 101, 103, 105 Randomized encouragement design, 174, 176, 218 RCTs. See Randomized controlled trials RD. See Regression discontinuity design Reach, 122, 141, 149, 168 defined, 218 Realist reviews, 63, 106, 138, 145, 153, 219 Recommendations, of the committee, 10–15, 201–206 building a resource base, 12–13, 203–204 communicating, disseminating, evaluating, and refining the L.E.A.D. framework, 14–15, 205–206 establishing standards for evidence quality, 13, 204 incorporating systems thinking, 12, 203 supporting the generation of evidence, 13–14, 204–205 utilizing the L.E.A.D. framework, 11–12, 202–203 Reductionist research, 62, 84 Refining the L.E.A.D. framework. See Evaluating and refining the L.E.A.D. framework Registry of reports establishing, 203–204 Regression discontinuity design, 101, 176, 180, 277–281 illustration using the example of an evaluation of the effect of school lunch programs on children’s health, 280 Replicability, 167 Reporting likely effectiveness, 152–153 Reporting likely reach and impact, 153 Reporting template, for summarizing evidence, 146–154 evidence table, 149–151 example L.E.A.D. framework evidence report, 148–149 questions asked by the decision maker, 147 strategies for locating evidence, 148–149 summary of evidence, 151–154 Representativeness, 122, 166–168. See also Generalizability; Reach Research designs, experimental and quasi-experimental common, 277–290 economic cost analysis, 288–290 interrupted time series analysis, 281–283 observational studies, 283–287 pre-/posttest designs, 287–288 regression discontinuity design, 279–281 a typology of research designs, 277 Research funders, 4, 22, 189. See also Target audiences recommendations for, 11, 13–15, 202–206 Research needed. See Needs assessments; Next steps Researchers, 3, 14, 189. See also Target audiences recommendations for, 11–15, 202–205 Resources needed, to utilize the L.E.A.D. framework, 11–12 Review of existing reviews on obesity prevention, 227–267 critical reviews, 260–261 integrative reviews, 230–231, 242–243, 250–251, 262–263 narrative reviews, 236–237, 248–249, 254–255 review of reviews, 250–251 reviews, 232–233, 258–259 synthesis research studies, 238–239 systematic reviews, 220, 228–235, 238–261 Risk factors. See Ethnicity; High-risk populations; Low-income Risk reduction approach, 37 Robert Wood Johnson Foundation, 20, 170, 197 Rubin’s perspective, 177–178, 279, 286 potential outcomes model, 177 RWJF. See Robert Wood Johnson Foundation S SAMHSA. See Substance Abuse and Mental Health Services Administration

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Scientific literature databases as evidence sources, 269–270 Secondary analysis as sources of evidence, 100–102 Selective interventions, 37–38, 141, 153 Sensitivity analysis, 176 Sesame Street program, 278 Shape Up Somerville, 95, 289 Simplified version of the causal loop obesity system map, 82 Simulation modeling, 79 Social determinants as areas of evidence needed, 91–93 defined, 220 Social marketing strategies, 38, 44–45 Society for Prevention Research, 123 Sources of evidence, 100–110, 140, 169–171. See also Gathering evidence; Identifying and locating evidence; Information sources for locating evidence Special Supplemental Nutrition Program for Women, Infants, and Children, 119 Specifying questions, 6–7 applying the evidence typology—an illustrative example, 98–100 an evidence typology for the L.E.A.D. framework, 91–100 “How” questions, 95–96 posing “Why,” “What,” and “How” questions after a policy or program is in place, 96–98 questions that guide the gathering of evidence, 91 “What” questions, 93–94 “Why” questions, 91–93 Spectrum of Prevention, 41, 46 Stable unit treatment value assumption, 177 Stakeholders, 15, 201, 206, 220. See also individual stakeholders Standards for evidence quality recommendations concerning, 13, 204 Statistical regression, 288 Status of the current evidence base, 56–59 choice of outcomes, 58–59 lack of conceptual frameworks, 57–58 quantity of available evidence, 57 review of existing reviews on obesity prevention, 227–267 Stocks and flows, 77. See also Systems thinking Strategic planning as areas of evidence needed, 95 Study approach, 3–4 Study designs and methodologies, an in-depth look, 277–300 economic cost analysis, 288–290 interrupted time series analysis, 281–283 mapping, 293 matching, 290–292 observational studies, 283–286 patching, 295–296 pooling, 293–294 pre-/posttest, 287–288 regression discontinuity, 279–281 typology of research designs, 277–279 Subpopulations affected, 24–26, 38 Substance Abuse and Mental Health Services Administration, 295 Summary of evidence, 151–154. See also Template for summarizing the evidence Surveys, 60 polls, and rankings as evidence sources, 272 as sources of evidence, 100–102 Sustainability as areas of evidence needed, 95–96 defined, 220 in evaluating impact of interventions, 144 SUTVA. See Stable unit treatment value assumption Syntheses existing tools, 144–146 of information from disparate sources, 139–141 methods, of evidence, 105–108, 126 of qualitative research, 107 research studies, 238–239 System dynamics, 74 Systematic reviews, 60, 105–106, 224–225 Systems approach, 71–74 Systems investigation, 74 Systems perspective, 5–6, 36, 64, 71–87, 221 importance of, 30 logic models and the complexity of interventions, 136–137 Systems science, 74 Systems theory, 74 Systems thinking, 74 concepts and variables in, 76–77 encouraging the use of, 12 increasing understanding of, 11 uses of, examples, 75–83 T Target audiences, of the L.E.A.D. framework, 3–4, 22, 188–190, 201 decision makers and intermediaries, 188–189 other important audiences, 189–190 publishers of research results, 190 research funders, 189 researchers, 189

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Bridging the Evidence Gap in Obesity Prevention: A Framework to Inform Decision Making Target populations, 38. See also Subpopulations affected Template for summarizing the evidence, 144, 146–154. See also Assembling evidence and informing decisions elements of the reporting template, 146–148 evidence table, 149–151 question asked by the decision maker, 147–148 strategy for locating evidence, 148–149 summary of evidence, 151–154 Texas, multi-level approach to childhood obesity prevention, 47–49 Tobacco control movement, 50–51, 75, 78–79, 140, 169 lessons for obesity prevention, 43, 46 sources of evidence, as natural experiments, 169 systems thinking, 75–79 Transdisciplinary research, 164–166 Transdisciplinary team science factors facilitating and constraining, 165 Transferability. See Generalizability Translation, 10, 32, 154, 201, 215, 221 of evidence, 96 of an intervention, 95–96 knowledge translation, 154 Transparency in decision making, 64 Transparent Reporting of Evaluations with Nonrandomized Designs, 121 Trends, in obesity rates, 23–26, 92 Typology of research designs, experimental and quasi-experimental, 277. See also Research designs U Universal interventions, 37–38, 40, 141, 153 “Upstream” approaches, 39 U.S. Centers for Disease Control and Prevention, 12, 20, 45, 49, 127, 169–170, 190, 197, 203, 291 U.S. Department of Agriculture, 192 U.S. Department of Health and Human Services, 192 Secretary of, 12–13, 203–204 U.S. Preventive Services Task Force, 121, 123, 127 U.S. Surgeon General, 50 USDA. See U.S. Department of Agriculture Uses of systems thinking, approaches, mapping, and modeling, 75–83 BMI screening in schools, 75 mapping of obesity causality in the United States, 79–81 obesity prevention in the United Kingdom, 80, 82–83 primer on concepts and variables in systems thinking, 76–77 the tobacco control movement, 75, 78–79 Using the L.E.A.D. framework, 4–10 assembling evidence and informing decisions, 8–9 evaluating evidence, 7–8 to inform decisions, 147 locating evidence, 7 opportunities to generate evidence, 9–10 recommendations concerning, 11–12, 202–203 specifying questions, 6–7 systems perspective, 5–6 USPSTF. See U.S. Preventive Services Task Force V Validity, 221. See also Generalizability; Level of certainty external, 7, 62, 64, 121–123, 168, 175 internal, 7, 62, 64, 175–176, 282, 284 VERBTM campaign, 45 W Washington State Department of Health, 152–153 “What if” scenarios, 83. See also Systems thinking “What” questions, 6–7, 93–94, 98–99 areas of concerns and examples of evidence needed, 93 posing “Why,” “What,” and “How” questions after a policy or program is in place, 96–98 what specifically should we do about this problem?, 136–142, 149–153 WHO. See World Health Organization “Why” questions, 6–7, 91–93, 96, 99 areas of concerns and examples of evidence needed, 92 posing “Why,” “What,” and “How” questions after a policy or program is in place, 96–98 why should we do something about this problem in our situation?, 135–136, 148, 150–151 WIC. See Special Supplemental Nutrition Program for Women, Infants, and Children Within-subjects design, 177. See also Rubin’s perspective Women’s Health Initiative Dietary Modification Trial, 173 World Cancer Research Fund, 40 World Health Organization, 37