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    • Appendix A

    Tables

    A-1

    		  

    Historical Review of the Biomarker–Surrogate Endpoint Literature with Special Reference to the Nomenclature, Initial Reports, Systems of Classification, and Statistical Methods Developed for Their Evaluation,

    		  

    252

    A-2

    		  

    Continuation of Table A-1 for 2007–2009,

    		  

    267

    Appendix B

    Boxes

    B-1

    		  

    Summary of Recommendations to Develop Biomarker-Based Tools for Cancer,

    		  

    278

    B-2

    		  

    Summary of Recommendations for The Future of Drug Safety: Promoting and Protecting the Health of the Public,

    		  

    279


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