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Research Training in the Biomedical, Behavioral, and Clinical Research Sciences Appendix A Committee Biographies Roger Chalkley, D. Phil., is senior associate dean of biomedical research education and training at the Vanderbilt School of Medicine. Dr. Chalkley is responsible for the overview of the activities of the Office of Biomedical Research Education and Training, including oversight of the Indisciplinary Graduate Program in the Biological Sciences, the M.D./Ph.D. program, postdoctoral affairs, and graduate student affairs as well as minority activities and supporting training grant applications. Dr. Chalkley was educated at Pembroke College, Oxford, in chemistry and did his postdoctoral research in gene regulation and chromatin structure in the laboratory of James Bonner at Caltech. After almost 20 years in the biochemistry department at the University of Iowa-School of Medicine, he moved to Vanderbilt in 1986. He has published almost 200 papers in chromatin research. Dr. Chalkley has had an active interest in graduate education for many years and was involved in the establishment of the IGP where he served as director for the past eight years. He has been a hardcore runner for 40 years and is a (self-described) competent rock climber. William T. Greenough, Ph.D. (Vice Chair) (NAS), is Swanlund Chair and Center for Advanced Study Professor of Psychology at the University of Illinois in Urbana-Champaign. His research focuses on neural mechanisms of learning and memory; neurobiology of long-term potentiation and epilepsy; mechanisms of the brain–behavioral development; neurobiology of the aging process; and plasticity of metabolic support components of the brain. Dr. Greenough’s awards and honors include AAAS fellow (1985), NIMH MERIT award (1989), member of the National Academy of Sciences (1992), Fragile X Foundation William Rosen Award for Outstanding Research (1998), University of Illinois Oakley-Kunde Award for Undergraduate Teaching (1998), and American Psychological Society William James Fellow Research Award (1998). He obtained his Ph.D. from the University of California at Los Angeles in 1969. He brings to the committee his knowledge of neuropsychology and learning processes, which is an important area of NIH research. He also has a broad knowledge of training and research issues through his research support from the National Institute of Aging, National Institute of Mental Health, and National Institute on Alcohol Abuse and Alcoholism. David Korn, M.D. (Vice Chair) (IOM), is presently the vice provost for research at Harvard University, a position he assumed in November 2008. Prior to that he served as chief scientific officer of the Association of American Medical Colleges (AAMC) in Washington, D.C., from January 2008 to November 2008 and as AAMC’s senior vice president for biomedical and health sciences research from September 1997 to January 2008. Before joining AAMC, Dr. Korn served as Carl and Elizabeth Naumann Professor and dean of the Stanford University School of Medicine from October 1984 to April 1995, and as vice president of Stanford University from January 1986 to April 1995. Before that he served as professor and chairman of the Department of Pathology at Stanford, and chief of the pathology service at the Stanford University Hospital since June 1968. Dr. Korn received his doctorate from Harvard University. He has been chairman of the Stanford University Committee on Research; president of the American Association of Pathologists (now the American Society for Investigative Pathology), from which he received the Gold-Headed Cane Award for lifetime achievement in 2004; president of the Association of Pathology Chairman; a member of the board of directors and the executive committee of the Federation of American Societies for Experimental Biology; and a member of the board of directors of the Association of Academic Health Centers. Dr. Korn was a founder and chairman of the board of directors of the California Transplant Donor Network, one of the nation’s largest organ procurement organizations. More recently, he was a founder of the Association for the Accreditation of Human Research Protection Programs, a nonprofit corporation created to enhance and standardize the protection of human participants in medical research. He is a member of the Institute of Medicine of the National Academy of Sciences and has served
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Research Training in the Biomedical, Behavioral, and Clinical Research Sciences on various National Academies committees, including the Clinical Research Roundtable. In the past decade his writings and lectures have focused on issues of academic values and health and science policy. Charles Bertolami, D.D.S., D. Med. Sc., is dean of the College of Dentistry at New York University. A leader in the dental research, education, and clinical communities, he was named the 14th dean of the 142-year-old New York University College of Dentistry in 2007. Dr. Bertolami was formerly the dean of the University of California-San Francisco (UCSF) School of Dentistry; during the 12 years he served in that post, the UCSF School of Dentistry led the nation in overall NIH funding for dental schools. In addition to expanding the school’s research capacity, he also enhanced the school’s clinical and teaching programs, including renovating clinics and laboratories; implemented a new curriculum reinforcing integration of basic and clinical sciences in dental education; established and expanded joint degree programs; and established a year-long post-baccalaureate program for students from economically or educationally disadvantaged groups. Dr. Bertolami is the president-elect of the American Dental Education Association and is a former president of the American Association for Dental Research. Thomas O. Daniel, M.D., is the president of Celgene Research. Dr. Daniel has more than two decades of medical and pharmaceutical research experience, having most recently served as the chief scientific officer at Ambryx, Inc., a biotechnology company focused on discovering and developing protein-based therapeutics. Prior to that, Dr. Daniel was vice president of research at Amgen Inc., where he served as research site head for Amgen Seattle, as inflammation therapeutic area head, and on research and development portfolio review boards. Prior to Amgen’s acquisition of Immunex, Dr. Daniel was senior vice president of discovery research at Immunex, where he consolidated and built programs in oncology and vascular biology. As president of Celgene Global Research, he is responsible for leading the discovery, preclinical, and early-stage clinical programs for Celgene worldwide. Prior to his industrial positions he was the K. M. Hakim Professor of Medicine and Cell Biology at Vanderbilt University, and director of the Vanderbilt Center for Vascular Biology. Dr. Daniel obtained his M.D. degree from University of Texas Southwestern, trained in internal medicine at Massachusetts General Hospital, completed postdoctoral work in molecular genetics at University of Texas Southwestern, was a Howard Hughes Medical Institute associate at UCSF, and an NIH-funded investigator for 20 years at Vanderbilt. His laboratory research programs focused on cellular and receptor mechanisms regulating endothelial growth and neovascularization. Margaret Grey, Dr.Ph.P.H., R.N., F.A.A.N. (IOM), is the dean and Annie Goodrich Professor at the Yale School of Nursing. She has been at Yale since January of 1993. Prior to assuming the deanship on September 1, 2005, she served as associate dean for scholarly affairs. She is also director of the NIH-funded Center for Self and Family Management and a related pre- and postdoctoral training program. She was the founding director of the school’s doctoral program. Previously she held progressive academic and administrative appointments at the University of Pennsylvania and Columbia University. She holds a bachelor’s degree from the University of Pittsburgh, an M.S.N. in pediatric nursing from Yale University, and a doctorate in public health and social psychology from Columbia University. James Jackson, Ph.D. (IOM), is Daniel Katz Distinguished University Professor of Psychology at the University of Michigan at Ann Arbor and director of the Institute for Social Research (ISR). Dr. Jackson’s research efforts include carrying out a number of national surveys and one international survey of black populations focusing on issues of racial and ethnic influences on life course development; attitude change; reciprocity; social support; and coping and health. He obtained his Ph.D. in social psychology from Wayne State University. Dr. Jackson is a recognized authority on African American life, and currently has a major grant from the National Institute of Mental Health to assess the physical, emotional, mental, and economic health of a nationally representative sample of more than 4,000 Black American adults. His knowledge and understanding of issues related to the underrepresentation of minority groups in biomedical, behavioral, and clinical research will be very helpful to the committee in addressing personnel needs in these populations. Keith Micoli, Ph.D., is the manager of the postdoctoral program and ethics program coordinator at New York University’s (NYU’s) School of Medicine. He earned his B.A. from New College of Florida in 1993 and his Ph.D. from the University of Alabama at Birmingham (UAB) in 2001, and, before moving to NYU in August 2008, was a postdoctoral fellow and instructor at UAB. He also held an appointment as adjunct assistant professor at Samford University, teaching microbiology. Keith served on the board of directors of the National Postdoctoral Association from 2003 to 2007 and was board chairman from 2005 to 2007. John C. Wooley, Ph.D., is associate vice chancellor for research at the University of California San Diego (UCSD), an adjunct professor in pharmacology and in chemistry and biochemistry, and a strategic advisor and senior fellow of the San Diego Supercomputer Center. He received his Ph.D. degree in 1975 at the University of Chicago, working with Al Crewe and Robert Uretz in biological physics. Prior to his appointment at UCSD he was at the Department of Energy, where he served as deputy associate director in the Office of Science. In that capacity, he was responsible for biological
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Research Training in the Biomedical, Behavioral, and Clinical Research Sciences and environmental sciences and oversaw human and microbial genomics, biotechnology, molecular and cell biology, health effects of radiation and energy production, computational and structural biology, and climate change research. Prior to going to the Department of Energy, he was the director of the Division of Infrastructure and Resources for the Biological Sciences Directorate at the National Science Foundation (NSF). For his role in advocating, establishing, and leading the Biological Instrumentation Facilities and the Biological Research Centers, Dr. Wooley received NSF’s top performance award, “NSF Superior Accomplishment.” He also held positions as a visiting scientist at G.D. Searle and Company in England, as an assistant professor of biochemical sciences at Princeton, and research associate professor of biophysics at Johns Hopkins Medical School. Dr. Wooley created the first programs within the U.S. federal government for funding research in bioinformatics and in computational biology, and has been involved in strengthening the interface between computing and biology for more than a decade. For the new UCSD California Institute for Telecommunication and Information Technology [Cal-(IT)2], Dr. Wooley directs the biology and biomedical layer or applications component, termed Digitally-enabled Genomic Medicine (DeGeM), a step in delivering personalized medicine in a wireless clinical setting. His current research involves bioinformatics and structural genomics, while his principal objective at UCSD is to stimulate new research initiatives for large-scale, multidisciplinary challenges. He also collaborates in developing scientific applications of information technology and high performance computing; creating industry–university collaborations; expanding applied life science opportunities, notably around drug discovery; and establishing a biotechnology and pharmacology science park on UCSD’s health sciences campus zone. Susan Fiske, Ph.D., is the Eugene Higgins Professor of Psychology at Princeton University. Dr. Fiske received her Ph.D. from Harvard University and has an honorary doctorate from Université Catholique de Louvain-la-Neuve, Belgium. Dr. Fiske’s research addresses how stereotyping, prejudice, and discrimination are encouraged or discouraged by social relationships, such as cooperation, competition, and power. She has just finished a third edition of Social Cognition (1984, 1991, 2008, each with Taylor) on how people make sense of each other. She has written more than nearly 200 articles and chapters and edited many books and journal special issues. Notably, she edits the Annual Review of Psychology (with Schacter and Sternberg) and the Handbook of Social Psychology (with Gilbert and Lindzey). She also wrote a recent upper-level text, Social Beings: A Core Motives Approach to Social Psychology (2004). She is a member of the American Academy of Arts and Sciences, past president of the Association for Psychological Sciences, and 2008 winner of the William James Fellow Award. Joan M. Lakoski, Ph.D., is the associate vice chancellor for academic career development and the founding and executive director of the Office of Academic Career Development at the University of Pittsburgh Health Sciences, associate dean for postdoctoral education, and professor of pharmacology at the University of Pittsburgh School of Medicine. Dr. Lakoski received her doctoral degree from the University of Iowa, completed postdoctoral training in the Department of Psychiatry at the Yale University School of Medicine, and has held faculty positions at the University of Texas Medical Branch in Galveston and the Pennsylvania State University College of Medicine, including interim chair of the Department of Pharmacology at Penn State. She maintains an active research program investigating the neuropharmacology of aging and impacts of mentoring, is a member of the graduate faculty at the University of Pittsburgh, and participates as a reviewer for NIH Center for Scientific Review study section panels. She has been the recipient of an NIH Research Career Development Award, an Independent Investigator Award from the National Alliance of Research on Schizophrenia, an administrative fellowship at the Pennsylvania State University, and a Committee on Institutional Cooperation Academic Leadership Program Fellow. Currently, she serves as chair of the Ethics Advisory Committee of the Endocrine Society, as a member of the AAMC Group on Faculty Affairs Program Planning and Transition Committee, as a member of the Board Development Committee for the National Postdoctoral Association, as a member of the Postdoctorate Committee for the AAMC Graduate Research and Education Training Group, as chair of the Committing on Teaching for the International Union of Pharmacology, as a AAMC women’s liaison officer for the University of Pittsburgh School of Medicine, and serves as co-director of the KL2 Clinical Research Scholars Program and director of mentoring and faculty development for the Clinical Translational Service Award at the University of Pittsburgh Schools of the Health Sciences. Her administrative responsibilities encompass oversight and development of comprehensive career development services, including mentoring programs for professional students, postdoctoral fellows, residents, clinical fellows, and faculty across the health schools at the University of Pittsburgh. She remains committed to creating and shaping the future of the biomedical research community. Mark Pauly, Ph.D. (IOM), received a Ph.D. in economics from the University of Virginia. Dr. Pauly is a former commissioner on the Physician Payment Review Commission and an active member of the Institute of Medicine. One of the nation’s leading health economists, Dr. Pauly has made significant contributions to the fields of medical economics and health insurance. His classic study on the economics of moral hazard was the first to point out how health insurance coverage may affect patients’ use of medical services. Subsequent work, both theoretical and empirical, has explored
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Research Training in the Biomedical, Behavioral, and Clinical Research Sciences the impact of conventional insurance coverage on preventive care, on outpatient care, and on prescription drug use in managed care. He is currently studying the effect of poor health on worker productivity. In addition, he has explored the influences that determine whether insurance coverage is available and, through several cost-effectiveness studies, the influence of medical care and health practices on health outcomes and cost. His interests in health policy deal with ways to reduce the number of uninsured people through tax credits for public and private insurance, and appropriate design for Medicare in a budget-constrained environment. Dr. Pauly is a co-editor-in-chief of the International Journal of Health Care Finance and Economics and an associate editor of the Journal of Risk and Uncertainty. He has served on Institute of Medicine panels on public accountability for health insurers under Medicare and on improving the supply of vaccines. Larry J. Shapiro, M.D. (IOM), is the executive vice chancellor for medical affairs at Washington University in St. Louis and dean of the school of medicine. Prior to his current position he was the W.H. and Marie Wattis Distinguished Professor and chair of the Department of Pediatrics at the University of California, San Francisco (UCSF), School of Medicine and has been the chief of pediatric services at UCSF Children’s Hospital since 1991. Dr. Shapiro is a member of the Institute of Medicine and the American Academy of Arts and Sciences. He is a fellow of the American Association for the Advancement of Science. Dr. Shapiro is a member of many professional societies and organizations and has served as the president of the American Society of Human Genetics, the American Board of Medical Genetics, the Society for Inherited Metabolic Diseases, the Western Society for Pediatric Research, the Society for Pediatric Research, and the American Pediatric Society. He is currently the chairman of the board of the Association of Academic Health Centers. Dr. Shapiro earned both undergraduate and medical degrees from Washington University in St. Louis. After completing his residency at St. Louis Children’s Hospital in 1973, he became a research associate at the National Institute of Arthritis, Metabolism and Digestive Diseases, Section on Human Biochemical Genetics. In 1975, he joined the faculty at the University of California, Los Angeles (UCLA) School of Medicine as an assistant professor of pediatrics and director of the Harbor-UCLA Genetic Metabolic Laboratory. Eight years later, Dr. Shapiro was named professor of pediatrics and biological chemistry, and in 1986 he became chief of the Division of Medical Genetics. While at UCLA, he was a Howard Hughes Medical Institute investigator. Edward H. Shortliffe is president and chief executive officer of the American Medical Informatics Association. He is also professor in the School of Biomedical Informatics at the University of Texas Health Science Center in Houston, Texas. Previously he was professor of biomedical informatics at Arizona State University and professor of basic medical sciences and professor of medicine at the University of Arizona College of Medicine. Until May 2008 he served as the founding dean of the Phoenix campus of the University of Arizona’s College of Medicine. Before that he was the Rolf A. Scholdager Professor and chair of the Department of Biomedical Informatics at Columbia College of Physicians and Surgeons in New York City (2000-2007) and professor of medicine and of computer science at Stanford University (1979-2000). After receiving an A.B. in applied mathematics from Harvard College in 1970, he moved to Stanford University where he was awarded a Ph.D. in medical information sciences in 1975 and an M.D. in 1976. During the early 1970s, he was principal developer of the medical expert system known as MYCIN. After a pause for internal medicine house-staff training at Massachusetts General Hospital and Stanford Hospital between 1976 and 1979, he joined the Stanford internal medicine faculty where he served as chief of general internal medicine, associate chair of medicine for primary care, and director of an active research program in clinical information systems and decision support. He spear-headed the formation of a Stanford graduate degree program in biomedical informatics and divided his time between clinical medicine and biomedical informatics research. He continues to be closely involved with medical education and biomedical informatics graduate training. His research interests include the broad range of issues related to integrated decision-support systems, their effective implementation, and the role of the Internet in health care. Dr. Shortliffe is a member of the Institute of Medicine, the American Society for Clinical Investigation, the Association of American Physicians, and the American Clinical and Climatological Association. He has also been elected to fellowship in the American College of Medical Informatics and the American Association for Artificial Intelligence. He is a master of the American College of Physicians and was a member of that organization’s board of regents from 1996-2002. He is editor-in-chief of the Journal of Biomedical Informatics and serves on the editorial boards for several other biomedical informatics publications. He has served on the Computer Science and Telecommunications Board (National Research Council) and the Biomedical Library Review Committee (National Library of Medicine) and was the recipient of a research career development award from the latter agency. In addition, he received the Grace Murray Hopper Award of the Association for Computing Machinery in 1976 and the Morris F. Collen Award of the American College of Medical Informatics in 2006 and has been a Henry J. Kaiser Family Foundation Faculty Scholar in general internal medicine. Donald Steinwachs, Ph.D. (IOM), is professor in the Health Policy and Management Department at Johns Hopkins University. He is also the director of the Health Services Research and Development Center there. Dr. Steinwachs
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Research Training in the Biomedical, Behavioral, and Clinical Research Sciences received his Ph.D. in 1973 from Johns Hopkins University. Dr. Steinwach’s current research seeks to identify opportunities to improve quality of health care and patient outcomes and when feasible, evaluate promising quality improvement interventions. Previous research includes studies of medical effectiveness and patient outcomes for individuals with specific medical (e.g., asthma), surgical (e.g., cataract surgery), and psychiatric (e.g., schizophrenia) conditions. A current study is evaluating an intervention with schizophrenia patients using a Web-based tool for patients to compare their care to evidence-based standards and empower them to discuss quality with their therapist. Valerie Petit Wilson is associate dean of the graduate school for recruitment and professional development (since 2005) and clinical professor of community health at Brown University. She is also executive director of the Leadership Alliance, a consortium of 33 leading teaching and research institutions dedicated to preparing underrepresented students for careers in academia, government, and private sectors through research and clinical doctoral training. In these roles Dr. Wilson is the principal investigator of numerous federal and private grants that enhance and support the development of undergraduate research scholars and promotes the development of a network of more than 2,000 Leadership Alliance alumni and doctoral scholars, She is also co-principal investigator for projects related to Brown’s participation in the Ph.D. Completion Project. Prior to beginning these appointments at Brown University, she was deputy director of the Center for Bioenvironmental Research and clinical professor of Environmental Health at Tulane University from 1998-2003. She previously directed the Division of Health Sciences Policy of the Institute of Medicine, National Academy of Sciences from 1993-1997. From 1981 to 1993 she held increasingly responsible positions at the National Institutes of Health and the Department of Health and Human Services, spanning biomedical research, research program administration, policy analysis, and policy development. Dr. Wilson’s expertise is in policy analysis, biomedical and environmental ethics, university administration, and workforce development. Dr. Wilson holds a B.S. degree in chemistry/pre-med from Xavier University of Louisiana and a Ph.D. in molecular biology from Johns Hopkins University, where she was supported by an NIH training grant and subsequently a Ford Foundation predoctoral fellow. Allan Yates, M.D., Ph.D., is an emeritus professor in the Department of Pathology and a previous director of the Medical Scientist Program at Ohio State University. Dr. Yates was also the previous vice-chair for research and graduate education in the Department of Pathology. The Medical Scientist Program at Ohio State, which leads to both the M.D. and Ph.D. degrees, has a unique, integrated curriculum that draws on the nationally recognized educational and scientific strengths of Ohio State University. Dr. Yates’ research involves investigating the role of glycolipids in the biology of human brain tumors. This includes glycolipid analyses, transfection of genes encoding enzymes that synthesize glycolipids, and examining the biological effects of altered glycolipid compositions of brain tumors both in cell culture and animal models. Dr. Yates was a fellow of the American College of Pathologists in 1991 and AAAS fellow in 2003. (Deceased August 2010)
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