Cover Image

HARDBACK
$69.95



View/Hide Left Panel

TABLE G-1 Case Studies of Vitamin D Toxicity

Study

Patient/Population

Preparation; Dose

Duration

Children

 

 

 

Djamil and Tu-Tunji. 1931. Lancet letter to the editor

2-yr-old male

Vigantol (irradiated ergosterol); 3 tsp

1 d

1947. BMJ letter to editor

Not specified

Cod liver oil

 

Ross. 1952. Journal of Pediatrics :815-822

4 infants ages 8-14 mo

Irradited ergosterol containing an estimated 30,000–40,000 IU vitamin

Daily for 8-12 mo

Jacqz et al. 1985

Infants with hypercalcemia (2 cases with vitamin D toxicity)

Vitamin D and calcium supplementation

 

 

Case 1: 3 mo old

 

 

 

Case 2: 7 mo old

300 μg D3

 

Besbas et al. 1989. Turkish J Pediatrics 31:239-244

Case 1: 3 mo old

Vitamin D: 45,000 IU/d

45 d

 

Case 2: 4 mo old

Vitamin D: 60,000 IU/d

30 d

Dent. 1964. BMJ letter to editor

6 yr old

Vitamin D (Calciferol Tablets B.P.): 1.25 mg. (~50,000 IU)/d

9 mo

Counts et al. 1975. Ann Internal Med 82:196-200

4-yr-old male

Vitamin D2 (Drisdol): 50,000 up to 100,000 IU/d

2 mo following bilateral nephrectomy

DeWind. 1960. Arch Dis Child 36:373-380

5.5 yr old

Vitamin D: 100,000 IU + cod liver oil-2 T + multivitamin

daily × 2–3 mo; and continued intake of tx vitamin D for 1 yr after hospitalization

Barrueto et al. 2005. Pediatrics 116:e453-e456

2-yr-old male

Vitamin D (ergocalciferol): 2,400,000 IU

4 d



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement