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TABLE 4-6 Serum 25OHD Levels and Bone Health Outcomes for Older Children and Adolescents: Summary from AHRQ-Ottawa Analysesa

Reference;

Country;

Jadad Score for RCTsb

Population Description

Intervention/Duration

Bone Health Outcomes

Results

RCTs

Ala-Houhala et al., 1988

Children, 8–10 y old

IG1: 400 IU vit D2 5–7×/wk

CG: placebo

Distal radius BMC (SPA)

Serum 25OHD, mean (SD) (nmol/L)

Baseline (winter):

IG1: 49.3 (19.0) vs. CG: 46.0 (15.5)

Mid-study (autumn):

IG1: 78.0 (24.3) vs. CG 59.0 (17.8)

End-of-study (winter):

IG1: 71.3 (23.4) vs. CG 43.3 (19.5), p < 0.01

 

 

n = 60

 

 

Finland

 

13 mo

 

 

IG1: 62% female

CG: 48% female

 

 

Jadad = 1

 

 

 

Caucasian

 

 

 

 

 

 

 

No difference between groups in distal radius BMC at 13 mo



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