. "4 Review of Potential Indicators of Adequacy and Selection of Indicators: Calcium and Vitamin D." Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press, 2011.
The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
Skin type III/IV (81% IV); mean age 8.9 (1.2) y (range 6–10 y)
400 IU vit D/d (isoform not specified)
iPTH (Immulite iPTH chemiluminescent assay)
Serum 25OHD, mean (SD) (nmol/L)
Baseline: 60.0 (26.3)
49% < 50
71% < 75
United States
1 mo
Group 1 = 25OHD < 50 nmol/L at baseline: 38.5 (8.0)
Group 2 = 25OHD > 50 nmol/L at baseline: 80.3 (20.5)
1 mo (total group): 68.8 (18.8)
Group 1: 57.5 (16.0)
Group 2: 79.5 (14.5)
Increase in serum 25OHD was observed only in group 1
7/39 (18%) of group 1 continued to have a level < 50 nmol/L after 1 mo of supplementation
Vit D dietary intake: mean (SD) 277 (146) IU/d 16/41 (39%) dietary intake < 200 IU/d
Negative correlation of 25OHD with body weight (r = −0.378, p = 0.015) at baseline
n = 42
34% female
No significant differences at baseline or 1 mo in markers of bone turnover, 1,25(OH)2D or PTH between groups with 25OHD < 50 nmol/L or > 50 nmol/L at baseline
African American
NOTE: BMAD = bone mineral apparent density; BMC = bone mineral content; BMD = bone mineral density; CG = control group; DXA = dual-energy X-ray absorptiometry; FN = femoral neck; IG = intervention group; iPTH = intact parathyroid hormone; IU = International Units; LS = lumbar spine; LSES = lower socioeconomic status; mo = month(s); NA = not applicable; PTH = parathyroid hormone; RCT = randomized controlled trial; SD = standard deviation; SPA = single-photon absorptiometry; UK = United Kingdom; USES = upper socioeconomic status; vit = vitamin; wk = week(s); y = year(s).
aThis table has been truncated for the purposes of this chapter, but it can be found in its entirety in Appendix C.
bJadad score is based on a scale of 1 to 5. See Box 4-1 for details on the scoring system.
