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Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
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Acronyms

AACI

Association of American Cancer Institutes

ACOSOG

American College of Surgeons Oncology Group

ACRIN

American College of Radiology Imaging Network

ALL

acute lymphoblastic leukemia

AMA

American Medical Association

AML

acute myeloid leukemia

ASCO

American Society of Clinical Oncology

ASO

administrative services only

BIQSFP

Biomarker, Imaging, and Quality of Life Studies Funding Program

BUN

blood urea nitrogen concentration

caBIG

Cancer Biomedical Informatics Grid

CALGB

Cancer and Leukemia Group B

CAM

complementary and alternative medicine

CBER

Center for Biologics Evaluation and Research

CCOP

Community Clinical Oncology Program

CCSG

Cancer Center Support Grant

CDER

Center for Drug Evaluation and Research

CDRH

Center for Devices and Radiological Health

CEBP

CCAAT/Enhancer Binding Protein

Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×

CED

coverage with evidence development

CIRB

Central Institutional Review Board

CLIA

Clinical Laboratory Improvement Amendments

CME

continuing medical education

CMS

Centers for Medicare and Medicaid Services

COG

Children’s Oncology Group

CPC

Cancer Prevention and Control

CPT

Common Procedural Terminology

CRADA

Cooperative Research and Development Agreement

CRF

case report form

CT

computed tomography

CTAC

Clinical and Translational Research Advisory Committee

CTEP

Cancer Therapy Evaluation Program

CTSU

Cancer Trials Support Unit

CTWG

Clinical Trials Working Group

DCTD

Division of Cancer Treatment and Diagnosis

ECOG

Eastern Cooperative Oncology Group

EMA

European Medicines Agency

ERISA

Employee Retirement Income Security Act

FDA

Food and Drug Administration

FLT3/ITD

fms-like tyrosine kinase receptor-3/internal tandem duplication

FOA

Funding Opportunity Announcement

GOG

Gynecological Oncology Group

HCPCS

Healthcare Common Procedure Coding System

HER2

human epidermal growth factor receptor 2

HHS

U.S. Department of Health and Human Services

IDE

investigational device exemption

IND

investigational new drug

IOM

Institute of Medicine

IP

intellectual property

IRB

Institutional Review Board

IT

information technology

Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×

KRAS

Kirsten ras oncogene

MTA

Material Transfer Agreement

NCCN

National Cooperative Cancer Network

NCCTG

North Central Cancer Treatment Group

NCI

National Cancer Institute

NDA

new drug applications

NHBLI

National Heart, Lung, and Blood Institute

NIH

National Institutes of Health

NLM

National Library of Medicine

NSABP

National Surgical Adjuvant Breast and Bowel Project

OEWG

Operational Efficiency Working Group

OHRP

Office for Human Research Protections

OPEN

Oncology Patient Enrollment Network

OSU

Ohio State University

PET-CT

positron emission tomography-computed tomography

PhRMA

Pharmaceutical Research and Manufacturers of America

PI

principal investigator

RECIST

Response Evaluation Criteria in Solid Tumors

RFA

Request for Applications

RTOG

Radiation Therapy Oncology Group

RUC

Relative Value Scale Update Committee

SACHRP

Secretary’s Advisory Committee on Human Research Protections

SJO

St. Joseph Hospital, Orange, California

sNDA

supplemental new drug application

SPA

Special Protocol Assessment

SPORE

Specialized Program of Research Excellence

START

Standard Terms of Agreement for Research Trials

SWOG

Southwest Oncology Group

TAILORx

Trial Assigning IndividuaLized Options for Treatment

TARGET

Therapeutically Applicable Research to Generate Effective Treatments

Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×

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Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×
Page 95
Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×
Page 96
Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×
Page 97
Suggested Citation:"Acronyms." Institute of Medicine. 2011. Implementing a National Cancer Clinical Trials System for the 21st Century: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13154.
×
Page 98
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Clinical trials enable scientific discoveries to advance patient care, in addition to informing and guiding subsequent research. The National Cancer Institute's (NCI's) Clinical Trials Cooperative Group Program works to advance patient care and research. The Cooperative Group Program has been instrumental in establishing the standards for cancer patient care and clinical research methods. Despite broad participation in the program, financial strain and procedural burdens limit the ability of the Cooperative Group Program to undertake medical practice-changing clinical research.

Thus, the Institute of Medicine's (IOM's) National Cancer Policy Forum and the American Society of Clinical Oncology held a workshop on March 21, 2011 to follow up on the 2010 IOM report, A National Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program, which made recommendations to strengthen the NCI Cooperative Group Program. In keeping with the established commitment to excellence Implementing a National Cancer Clinical Trials System for the 21st Century outlines how to improve the current system by incorporating innovative science and trial design into cancer clinical trials. It also examines the impact of increasing quality in regards to speed, efficiency, design, launch, and conduct, as well as improving prioritization, and incentivized participation.

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