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Appendix F
Committee Biosketches
Ellen Wright Clayton, J.D., M.D. (Chair), is Craig-Weaver Chair in Pediat-
rics as well as Professor of Law and the Director of the Center for Biomedi-
cal Ethics and Society at Vanderbilt University. Her research and teaching
interests include pediatrics, medical and research ethics, legal and ethical
issues in children’s and women’s health, and genetics and health policy. She
has served as a member on numerous committees for the National Institutes
of Health as well as the Ethical, Legal, and Social Issues Working Group
of the Newborn Screening Taskforce, Maternal and Child Health Bureau,
Health Resources Services Administration. Dr. Clayton has served as a con-
sultant to the Food and Drug Administration on the topic of clinical phar-
macology during pregnancy. She is a member of the Institute of Medicine
(IOM) and has served on several National Academies committees as well
as the IOM’s Health Sciences Policy Board and is currently a member of its
National Advisory Council. She has numerous publications in books, medi-
cal journals, interdisciplinary journals, and law journals on the intersection
of law, medicine, and public health. Dr. Clayton received her M.D. from
Harvard University in 1985 and her J.D. from Yale University in 1979.
Inmaculada B. Aban, Ph.D., M.S., is currently an Associate Professor in
the Research Methods and Clinical Trials Section in the Department of
Biostatistics at University of Alabama at Birmingham. She has considerable
experience in clinical studies and statistical methodology research. She was
Director of the Biostatistics Core of the National Institutes of Health (NIH)/
National Heart, Lung, and Blood Institute (NHLBI)-sponsored SCCOR
Program on Heart Failure that ended in 2010. She is currently the Deputy
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828 ADVERSE EFFECTS OF VACCINES: EVIDENCE AND CAUSALITY
Director of an international multicenter Data Coordinating Center funded
by the National Institute of Neurological Disorders and Stroke (NINDS) on
myasthenia gravis, a rare disease. She serves as the primary Biostatistician
for Collaborative Antiviral Study Group pediatric trials on rare diseases.
She also provides statistical support regarding study design, protocol de-
velopment, study monitoring, quality assurance, report generation, and
statistical analyses. She has years of experience in writing and presenting
Data and Safety Monitoring Board (DSMB) reports. She served as a DSMB
member in an NIH/NINDS study and had served as a temporary member of
NHLBI study sections. Her current research interests are statistical methods
in clinical trials, survival and reliability analysis, analysis of pool screening
and count data, goodness-of-fit and model diagnostics, inference for heavy
tail distribution, and propensity scores applied to epidemiologic data.
Douglas J. Barrett, M.D., is a Professor in the Department of Pediatrics,
the Department of Molecular Genetics & Microbiology, and the Depart-
ment of Pathology, Immunology, & Laboratory Medicine at the University
of Florida College of Medicine. Dr. Barrett is a practicing pediatrician,
a researcher, and the author or coauthor of three books, several book
chapters, and more than 110 journal articles. Dr. Barrett’s clinical and
research expertise is in childhood immune responses, immunodeficiency
diseases, and transplantation. His research has been supported by grants
from the National Institutes of Health, the American Heart Association, and
the American Cancer Society. Dr. Barrett is active in the American Acad-
emy of Pediatrics, American Board of Pediatrics, Association for Academic
Health Centers, and the Society for Pediatric Research. He serves on the
editorial board for Contemporary Pediatrics and is a reviewer for multiple
journals. Dr. Barrett received his M.D. in 1974 as a charter class member
of the University of South Florida College of Medicine. He completed his
pediatric internship training at Tampa General Hospital and All Children’s
Hospital. After completing a pediatric residency at SUNY/Upstate Medical
Center in New York, he pursued fellowship training in pediatric immunol-
ogy in the Department of Pediatrics at the University of California, San
Francisco. Dr. Barrett joined the University of Florida in 1980. He served
as the Chief of the Division of Pediatric Immunology from 1986 to 1990,
as the Chairman of the Department of Pediatrics from 1990 to 2001, and
as Senior Vice President for Health Affairs at the University of Florida from
2001 to 2009. In the latter position he was responsible for maximizing the
performance of the educational, research, and clinical programs in the six
colleges of the University of Florida’s Health Sciences Center.
Martina Bebin, M.D., M.P.A., is associate professor of neurology and pe-
diatrics at the University of Alabama at Birmingham. She is a practicing
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APPENDIX F
child neurologist, and her research interests include pediatric clinical drug
development for epilepsy and outcomes research of epilepsy patients, with
a focus on treatment of epilepsy in children. She has clinical responsibility
for the care of children enrolled in a clinical trial supported by Novartis
for treatment of tuberous sclerosis patients with subependymal giant cell
tumors of the brain. She is currently working on the Tuberous Sclerosis
Alliance Natural History Database Project, funded by the Tuberous Scle-
rosis Alliance and the Centers for Disease Control and Prevention. She is a
former Robert Wood Johnson Foundation Health Policy fellow. Dr. Bebin
received her M.D. from the University of Mississippi School of Medicine
in 1986. She completed her pediatric and neurology training at the Mayo
Clinic in Rochester, Minnesota, and a fellowship in epilepsy at the Univer-
sity of Virginia. In 2005 she earned her M.P.A. from Harvard University-
Kennedy School of Government.
Kirsten Bibbins-Domingo, Ph.D., M.D., M.A.S., is associate professor of
medicine and epidemiology and biostatistics at the University of California,
San Francisco, and an attending physician at San Francisco General Hos-
pital. Dr. Bibbins-Domingo is an active researcher in preventive cardiology,
the epidemiology of cardiovascular disease in young adults, and race and
gender health and health care disparities. Her research has examined the
development of cardiovascular risk factors in young adults, the effectiveness
of screening and diagnostic tests for cardiovascular disease, and computer-
simulated projections of future cardiovascular disease trends and the impact
of public health and clinical interventions on cardiovascular disease preven-
tion. Dr. Bibbins-Domingo served on the IOM Committee on Evaluation
of the Presumptive Disability Decision-Making Process for Veterans from
2006 to 2007. She received her undergraduate degree in molecular biology
and public policy from Princeton University and her medical degree, Ph.D.
in biochemistry, and Masters of Clinical Research from the University of
California, San Francisco.
Martha Constantine-Paton, Ph.D., is investigator at the McGovern Institute
for Brain Research and Professor in the departments of Brain and Cognitive
Sciences and Biology at the Massachusetts Institute of Technology (MIT).
Previously, she was professor of biology at Yale University from 1985 until
1999, and a faculty member at Princeton University from 1976 through
1984, before joining MIT in 1999. Dr. Constantine-Paton studies activity-
dependent brain development, glutamate receptor regulation, and physiol-
ogy of the developing visual system in animal models. She is interested in
the biochemical, structural, or genetic programs that cause the developing
brain to lose its plasticity or to compensate for genetic mutations or trauma
as the brain matures, possibly leading to loss of learning and memory or to
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830 ADVERSE EFFECTS OF VACCINES: EVIDENCE AND CAUSALITY
neurological or neuropsychiatric disease. Dr. Constantine-Paton earned her
Ph.D. in 1976 from Cornell University. She has received a number of honors
and awards, among them the Young Investigator Award from the Society of
Neuroscience and a Merit Award from the National Eye Institute. She has
served on numerous committees and councils. She has previously worked
for the Institute of Medicine on panels that suggested new nutritional
guidelines and explored the ethics and value of fetal tissue use. She has
been a member of several grant review panels at the National Institutes of
Health, including the National Advisory Eye Council and the Child Council
Workgroup for the National Institute of Mental Health.
Deborah J. del Junco, Ph.D., is the director of outcomes research at the
Center for Translational Injury Research and senior epidemiologist at the
Center for Clinical and Translational Sciences at the University of Texas
Health Science Center-Houston (UTHealth-H). She is associate profes-
sor in the Departments of Surgery and Pediatrics (UTHealth-H School of
Medicine) and the Division of Epidemiology, Human Genetics and Envi-
ronmental Sciences (UTHealth-H School of Public Health). Her research
and teaching have focused on epidemiology methods, gene-environment,
and other complex interactions among etiologic factors in chronic disease,
records linkage, meta-analysis, reproductive health, autoimmune disease,
and Rett syndrome. She is a Fellow of the American College of Epidemiol-
ogy and has served as an executive editor of Epidemiologic Perspectives and
Innovations. She has many publications in peer-reviewed journals and has
served on a large number of review panels and advisory committees for the
National Institutes of Health, Centers for Disease Control and Prevention,
and Department of Defense. Dr. del Junco completed a fellowship in the
Department of Epidemiology and Biostatistics at the Mayo Clinic in Roch-
ester, Minnesota, in 1984 and received her Ph.D. in epidemiology from the
University of Texas Houston Health Science Center in 1988.
Betty A. Diamond, M.D., is head of the Center for Autoimmune and Mus-
culoskeletal Disease at the Feinstein Institute for Medical Research. Her
research has focused on the immune system and autoimmune diseases, with
an interest in systemic lupus erythematosus. Dr. Diamond is a practicing
rheumatologist and has received many honors, including the Outstanding
Investigator Award from the American College of Rheumatology, the Lee
Howley Award from the Arthritis Foundation, the Recognition Award
from the National Association of M.D.-Ph.D. Programs, and election to
the Institute of Medicine. She has served on the Scientific Council of the
National Institute of Arthritis and Musculoskeletal and Skin Diseases, and
the Board of Directors of the American College of Rheumatology, and is
a past-president of the American Association of Immunologists. She has a
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APPENDIX F
grant from Autism Speaks to study the effects of maternal autoantibodies
on fetal development. Dr. Diamond earned her medical degree from Har-
vard Medical School in 1973, and then completed a residency in internal
medicine at Columbia Presbyterian Medical Center and a postdoctoral fel-
lowship in immunology at the Albert Einstein College of Medicine.
S. Claiborne Johnston, M.D., Ph.D., is Associate Vice Chancellor of Re-
search, Director of the Clinical and Translational Science Institute, Profes-
sor of Neurology and Epidemiology, and Director of the Stroke Service at
the University of California, San Francisco. He is a practicing neurologist,
and his research has focused on stroke treatment and prevention. In the
past, he has had funding from both Sanofi and Novartis to study drugs
used in the treatment of stroke. His current funding from NINDS oversees
the POINT multicenter randomized trial of Clopidogrel versus placebo
in patients taking aspirin after TIA or minor ischemic stroke. He is also
PI of a large trial of platinum versus coated coils in treating intracranial
aneurysms sponsored by Stryker. Dr. Johnston has authored over 250 pub-
lications in scientific journals and has won several national awards for his
research and teaching. He was a member of the California Health Disease
and Stroke Prevention Advisory Council, which advises the Department
of Health Services, and was co-director of Prevention Education Programs
for the National Stroke Association. Dr. Johnston received his M.D. from
Harvard Medical School and Ph.D. in epidemiology from the University of
California, Berkeley School of Public Health.
Anthony L. Komaroff, M.D., is the Steven P. Simcox, Patrick A. Clifford,
and James H. Higby Professor of Medicine at Harvard Medical School,
senior physician at Brigham and Women’s Hospital, and editor-in-chief of
Harvard Health Publications. He was director of the Division of General
Medicine and Primary Care at Brigham and Women’s Hospital for 15 years
and is the founding editor of Journal Watch, a summary medical informa-
tion newsletter for physicians published by the Massachusetts Medical
Society. Dr. Komaroff practices internal medicine (primary care and con-
sultative medicine). For 25 years, he has conducted research on chronic fa-
tigue syndrome, including studies of the prevalence of the illness, symptom
presentation, and functional capacity, as well as virologic, immunologic,
and neurologic studies. He is the author of over 200 journal articles, several
book chapters, and one book, and is a fellow of the American College of
Physicians and of the American Association for the Advancement of Sci-
ence. Dr. Komaroff received his M.D. from the University of Washington.
B. Paige Lawrence, Ph.D., is associate professor of environmental medicine
and microbiology and immunology at the University of Rochester School
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832 ADVERSE EFFECTS OF VACCINES: EVIDENCE AND CAUSALITY
of Medicine and Dentistry. Dr. Lawrence’s research is focused on defining
the cellular and molecular mechanisms by which environmental factors
adversely affect the development and function of the immune system. This
work includes the impact of acute exposure to environmental contaminants
and pharmacological agents, as well as the consequences of prenatal (ma-
ternal) exposures on immune function in the next generation. Her work has
shown that an environment-sensing transcription factor may have a com-
plex mediating effect in the body, and results have demonstrated impacts
on immune system function, including inflammatory responses and fighting
viral infections. Dr. Lawrence has numerous peer-reviewed publications and
professional awards, and serves on the editorial board for several toxicol-
ogy journals. She has also served as a member of a science advisory panel
for the U.S. Environmental Protection Agency and provides service to vari-
ous review committees for the National Institutes of Health. She received
her Ph.D. in cell biology from Cornell University in 1993, and postdoctoral
training in immunology and toxicology at Oregon State University.
M. Louise Markert, M.D., Ph.D., is associate professor of pediatrics and
immunology in the Division of Pediatric Allergy and Immunology at Duke
University School of Medicine. Dr. Markert has pioneered the development
of thymus transplantation for T cell reconstitution in infants born with
complete DiGeorge anomaly. DiGeorge anomaly is a congenital disorder
characterized by defects of the heart, parathyroid, and thymus. Complete
DiGeorge anomaly is fatal because of the absence of functional thymus
leading to profound primary immunodeficiency. In research protocols to
date, 61 infants with complete DiGeorge anomaly have been transplanted
with postnatal cultured human thymic epithelial tissue. Over 70 percent of
these infants survive and have developed functional T cells. Dr. Markert
graduated from Smith College with a B.A. in biochemistry and then com-
pleted the M.D./Ph.D. program at Duke University. She received her Ph.D.
in immunology, completed a 2-year pediatric residency at Duke, and then a
3-year fellowship in pediatric allergy and immunology. Dr. Markert joined
the Duke faculty in 1987. She was program director of the Duke NIH-
funded General Clinical Research Center from 1993 to 2004. From 1996
to 2004, she served on the American Board of Allergy and Immunology and
was chair of the Board in 2002. Dr. Markert has published over 40 research
articles plus invited chapters and reviews.
Marc C. Patterson, M.D., is chair of the Division of Child and Adolescent
Neurology and professor of neurology, pediatrics, and medical genetics at
Mayo Clinic. Dr. Patterson is a child neurologist with special expertise in
neurometabolic and neurogenetic disorders. His research has focused on
neurometabolic disorders, with a particular focus on Niemann-Pick disease,
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APPENDIX F
Type C, Gaucher disease, and congenital disorders of glycosylation. Dr.
Patterson was born and educated in Australia, where he graduated from
the University of Queensland, before training in medicine, pediatrics, and
neurology at the Royal Brisbane, Royal Children’s, and Royal Women’s
Hospitals in Brisbane. He completed further training in pediatrics and
child neurology at Mayo Graduate School of Medicine, and a fellowship
in neurometabolic diseases with Roscoe Brady at the National Institutes
of Health. On completion of training, Dr. Patterson joined the staff of
Mayo Clinic and faculty of Mayo Medical School, where he was associ-
ate professor in the Departments of Neurology, Pediatric and Adolescent
Medicine, and Medical Genetics. In 2001, he moved to New York and was
professor of clinical neurology and pediatrics at Columbia University and
director of pediatric neurology at the Neurologic Institute of New York
and Children’s Hospital of New York–Presbyterian. In 2007, he returned
to the Mayo Clinic.
Hugh A. Sampson, M.D., is professor of pediatrics and immunology at
the Mount Sinai School of Medicine. He is also director of the Jaffe Food
Allergy Institute, dean for Translational Biomedical Sciences at the Mount
Sinai Medical Center, and a practicing pediatric allergist. Dr. Sampson’s
research has focused on food allergic disorders, including work on the
immuno-pathogenic role of food hypersensitivity in atopic dermatitis,
the pathogenesis of food-induced anaphylaxis, characterization of food-
induced gastrointestinal hypersensitivities, and immunotherapeutic strate-
gies for treating food allergies. He holds a patent for a potential treatment
vaccine for peanut allergy. Dr. Sampson is the past president of the Ameri-
can Academy of Allergy, Asthma, and Immunology and a member of the In-
stitute of Medicine. He is a co-editor of Pediatric Allergy and Immunology
and has served on the editorial board of the Journal of Allergy and Clinical
Immunology, and Clinical and Experimental Allergy. Dr. Sampson received
his medical degree from the State University of New York, then finished a
residency in pediatrics at the Children’s Memorial Hospital, and completed
a fellowship in allergy and immunology at Duke University.
Pauline A. Thomas, M.D., is associate professor in the Department of
Preventive Medicine and Community Health in the New Jersey Medical
School, and associate professor in the School of Public Health at the Uni-
versity of Medicine and Dentistry of New Jersey. She is Co-Director of the
NJMS Preventive Medicine Residency, and is also a practicing pediatrician.
Her research interests include pediatric HIV, public health practice and
surveillance methodology, and health care delivery. She served as assistant
commissioner for surveillance in the Division of Epidemiology at the New
York City Department of Health and Mental Hygiene and director of the
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834 ADVERSE EFFECTS OF VACCINES: EVIDENCE AND CAUSALITY
Health Department’s Office of AIDS Surveillance. Dr. Thomas received
her medical degree from Yale University School of Medicine in 1977 and
completed her residency in pediatrics at Strong Memorial Hospital of the
University of Rochester, New York. Following residency she worked 2 years
with the Centers for Disease Control and Prevention as an epidemic intel-
ligence service officer.
Leslie P. Weiner, M.D., is professor of neurology and molecular microbiol-
ogy and immunology and holds the Richard Angus Grant, Sr., Chair in
Neurology at the Keck School of Medicine of the University of Southern
California (USC). Dr. Weiner earned his medical degree from the University
of Cincinnati and completed his neurology residency at the Johns Hopkins
Hospital. At Johns Hopkins, he also pursued a fellowship in neurology and
epidemiology, focusing on viruses of the nervous system. He then completed
a fellowship at the National Institutes of Health Laboratory of Slow Virus
Infections. Dr. Weiner served as chair of the USC Department of Neurology
for 25 years and he remains a practicing neurologist. Dr. Weiner’s research
interests include a human T cell vaccine for the treatment of secondary pro-
gressive multiple sclerosis (MS), gene therapy for MS, molecular mimicry,
and, more recently, neural stem cells. He has written more than 200 papers
and has received numerous honors. He served as an expert witness for a
federal judge in cases regarding adverse effects of the swine flu vaccine in
the 1970s.
