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Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
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Acronyms

AIDS

acquired immunodeficiency syndrome

 

BATTLE

Biomarker-based Approaches of Targeted Therapy for Lung Cancer Elimination

BRAF

Rapidly Accelerated Fibrosarcoma (B family)

 

CaBIG

cancer Biomedical Informatics Grid

CDER

Center for Drug Evaluation and Research

CDRH

Center for Devices and Radiological Health

CEO

chief executive officer

CGL

chronic granulocytic leukemia

CITN

Cancer Immunotherapy Trials Network

CMS

Center for Medicare & Medicaid Services

CRADA

Cooperative Research and Development Agreement

CTEP

Cancer Therapy Evaluation Program

CTLA-4

Cytotoxic T-Lymphocyte Antigen 4

 

DCE-MRI

dynamic contrast enhanced-magnetic resonance imaging

DOJ

Department of Justice

 

EGFR

epidermal growth factor receptor

EMA

European Medicines Agency

ER

estrogen-receptor

Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
×

FDA

Food and Drug Administration

FNIH

Foundation for the National Institutes of Health

FTC

Federal Trade Commission

 

GSK

GlaxoSmithKline

 

HER2

human epidermal growth factor receptor 2

HIV

Human Immunodeficiency Virus

HPV

human papillomavirus

 

IGF

insulin-like growth factor

IIP

instantaneous inhibitory potential

IND

Investigational New Drug

IP

intellectual property

IRB

Institutional Review Board

I-SPY TRIAL

Investigation of Serial studies to Predict Your Therapeutic Response with Imaging And moLecular analysis

 

LCMV

lymphocytic choriomeningitis virus

 

MAPK

mitogen-activated protein kinase

MEK

mitogen-activated protein kinase kinase

MET

Methylnitronitrosoguanidine-HOS (Human osteosarcoma) Transforming gene

MTA

Material Transfer Agreement

mTORC1

mammalian target of rapamycin complex-1

 

NCDDG

National Cooperative Drug Discovery Groups

NCI

National Cancer Institute

NERF

non-exclusive royalty-free

NIAID

National Institute of Allergy and Infectious Diseases

NIH

National Institutes of Health

NOD

non-obese diabetic

 

OS

overall survival

 

PathCR

pathological complete response

PET

positron emission tomography

PFS

progression-free survival

PI3K

phosphatidylinositol 3-kinase

PPTP

Pediatric Preclinical Testing Program

 

R&D

research and development

Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
×

SOC

standard of care

START

Standard Terms of Agreement for Research Trial

 

VEGF

vascular endothelial growth factor

Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
×

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Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
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Page 101
Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
×
Page 102
Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
×
Page 103
Suggested Citation:"Acronyms." Institute of Medicine. 2012. Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13262.
×
Page 104
Facilitating Collaborations to Develop Combination Investigational Cancer Therapies: Workshop Summary Get This Book
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Advances in biomedical research have increased our understanding of the complex nature of disease and the interaction of multiple molecular pathways involved in cancer. Combining investigational products early in their development is thought to be a promising strategy for identifying effective therapies. The IOM's National Cancer Policy Forum held a workshop to discuss challenges and identify potential solutions to improve collaboration and advance the development of combination investigational cancer therapies.

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