betes. Well known for his inspired teaching, Dr. Rubenstein has served in numerous professional leadership positions during his career. These include President of the Association of Professors of Medicine, President of the Association of American Physicians, President of the Central Society for Clinical Research, Chairman of the American Board of Internal Medicine, Chairman of the Board of the Association of Academic Health Centers, and Chair of the National Diabetes Advisory Board. He has been a member of a study section and of the Advisory Council of the National Institute of Diabetes and Digestive and Kidney Diseases. Author of more than 350 publications, Dr. Rubenstein has held editorial advisory positions with several respected journals, including service on the editorial boards of the Annals of Internal Medicine, the Journal of Diabetes and Its Complications, Medicine, and Clinical Trials Advisor. He was also a consulting editor to the Journal of Clinical Investigation. Dr. Rubenstein is the recipient of many awards and prizes, including the highest honor from the Association of Professors of Medicine, the Robert H. Williams Distinguished Chair of Medicine Award. Among his other honors are the John Phillips Memorial Award from the American College of Physicians; the Banting Medal from the American Diabetes Association; and the David Rumbough Scientific Award from the Juvenile Diabetes Association. In 2009, Dr. Rubenstein was awarded the prestigious Abraham Flexner Award for Distinguished Service to Medical Education from the Association of American Medical Colleges. Born in South Africa, Dr. Rubenstein received his medical degree from the University of the Witwatersrand in Johannesburg. In 2001, he was honored by his alma mater when an honorary degree, Doctor of Science in Medicine, was conferred upon him. He is a Fellow of the College of Medicine of South Africa and of the Royal College of Physicians of London; a Master of the American College of Physicians; American Academy of Arts and Sciences; and a member of the IOM of the National Academy of Sciences.

Richard A. Rudick, M.D., Professor of Medicine, Cleveland Clinic Lerner College of Medicine Hazel Prior Hostetler Chair of Neurology, Cleveland Clinic Director, Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Vice Chairman, Research and Development in the Neurological Institute, Cleveland Clinic. Dr. Rudick graduated from Case Western Reserve University School of Medicine in 1975. Following internship and residency in medicine at the University of Connecticut, Dr. Rudick trained in neurology at the University of Rochester. During a postdoctoral research fellowship in the Center for Brain Research at the University of Rochester, studies focused on neurologic consequences of immune complex disease in animal systems and immunologic abnormalities in multiple sclerosis (MS) patients. Dr. Rudick’s subsequent studies

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