National Academies Press: OpenBook
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

 

 

THE ROLE OF
OBESITY

IN CANCER SURVIVAL AND RECURRENCE
WORKSHOP SUMMARY

 

 

 

 

National Cancer Policy Forum
Board on Health Care Services
Margie Patlak and Sharyl J. Nass, Rapporteurs

INSTITUTE OF MEDICINE

             OF THE NATIONAL ACADEMIES

 

 

THE NATIONAL ACADEMIES PRESS
Washington, D.C.
www.nap.edu

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

THE NATIONAL ACADEMIES PRESS   500 Fifth Street, NW   Washington, DC 20001

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine.

This study was supported by Contract Nos. HHSN261200900003C and 200-2005-13434 TO #1 between the National Academy of Sciences and the National Cancer Institute and the Centers for Disease Control and Prevention, respectively. In addition, the National Cancer Policy Forum is also supported by the American Association for Cancer Research, the American Cancer Society, the American Society of Clinical Oncology, the Association of American Cancer Institutes, Bristol-Myers Squibb, C-Change, the CEO Roundtable on Cancer, Novartis Oncology, and the Oncology Nursing Society. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the organizations or agencies that provided support for this project.

International Standard Book Number-13: 978-0-309-25333-8
International Standard Book Number-10: 0-309-25333-0

Additional copies of this report are available from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.

For more information about the Institute of Medicine, visit the IOM home page at: www.iom.edu.

Copyright 2012 by the National Academy of Sciences. All rights reserved.

Printed in the United States of America

Cover credit: Design by Casey Weeks.

The serpent has been a symbol of long life, healing, and knowledge among almost all cultures and religions since the beginning of recorded history. The serpent adopted as a logotype by the Institute of Medicine is a relief carving from ancient Greece, now held by the Staatliche Museen in Berlin.

Suggested citation: IOM (Institute of Medicine). 2012. The role of obesity in cancer survival and recurrence: Workshop summary. Washington, DC: The National Academies Press.

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

 

“Knowing is not enough; we must apply.
Willing is not enough; we must do.”
    
                                                —Goethe

 

 

 

 

 

 

 

 

 

 

img

INSTITUTE OF MEDICINE
             OF THE NATIONAL ACADEMIES

Advising the Nation. Improving Health.

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

THE NATIONAL ACADEMIES

Advisers to the Nation on Science, Engineering and Medicine

The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. Dr. Ralph J. Cicerone is president of the National Academy of Sciences.

The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers. It is autonomous in its administration and in the selection of its members, sharing with the National Academy of Sciences the responsibility for advising the federal government. The National Academy of Engineering also sponsors engineering programs aimed at meeting national needs, encourages education and research, and recognizes the superior achievements of engineers. Dr. Charles M. Vest is president of the National Academy of Engineering.

The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National Academy of Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, to identify issues of medical care, research, and education. Dr. Harvey V. Fineberg is president of the Institute of Medicine.

The National Research Council was organized by the National Academy of Sciences in 1916 to associate the broad community of science and technology with the Academy’s purposes of furthering knowledge and advising the federal government. Functioning in accordance with general policies determined by the Academy, the Council has become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities. The Council is administered jointly by both Academies and the Institute of Medicine. Dr. Ralph J. Cicerone and Dr. Charles M. Vest are chair and vice chair, respectively, of the National Research Council.

www.national-academies.org

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

WORKSHOP PLANNING COMMITTEE1

 

WENDY DEMARK-WAHNEFRIED (Chair), Professor and Webb Endowed Chair of Nutrition Sciences, Associate Director, University of Alabama at Birmingham Comprehensive Cancer Center

RACHEL M. BALLARD-BARBASH, Associate Director, Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD

THOMAS G. BURISH, Provost, Notre Dame University, South Bend, IN

PATRICIA A. GANZ, Professor, University of California, Los Angeles, School of Medicine & Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Center

PAMELA J. GOODWIN, Senior Scientist, Samuel Lunenfeld Research Institute, Marvelle Koffler Chair in Breast Research, Professor of Medicine, University of Toronto Mount Sinai Hospital, Ontario, Canada

STEPHEN D. HURSTING, Professor and McKean Love Chair, Department of Nutritional Sciences, University of Texas at Austin

MARTIN J. MURPHY, Chief Executive Officer, CEO Roundtable on Cancer, Durham, NC

LISA C. RICHARDSON, Associate Director for Science, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA

Project Staff

SHARYL J. NASS, Director, National Cancer Policy Forum

ERIN BALOGH, Associate Program Officer

NIHARIKA SATHE, Research Assistant (until March 2012)

PAMELA LIGHTER, Research Assistant (from March 2012)

MICHAEL PARK, Senior Program Assistant

ROGER HERDMAN, Director, Board on Health Care Services

_________________

1 Institute of Medicine planning committees are solely responsible for organizing the workshop, identifying topics, and choosing speakers. The responsibility for the published workshop summary rests with the workshop rapporteurs and the institution.

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

This Page is Blank

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

NATIONAL CANCER POLICY FORUM1

JOHN MENDELSOHN (Chair), Codirector, Khalifa Institute for Personalized Cancer Therapy, MD Anderson Cancer Center, Houston, TX

PATRICIA A. GANZ (Vice Chair), Professor, University of California, Los Angeles, School of Medicine & Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Center

AMY ABERNETHY, Associate Professor of Medicine, Duke University School of Medicine, and Director, Duke Cancer Care Research Program, Durham, NC

FRED APPELBAUM, Director, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA

PETER B. BACH, Attending Physician, Memorial Sloan-Kettering Cancer Center, New York

EDWARD BENZ, JR., President, Dana-Farber Cancer Institute and Director, Harvard Cancer Center, Harvard School of Medicine, Boston, MA

MONICA BERTAGNOLLI, Professor of Surgery, Harvard University Medical School, Boston, MA

OTIS BRAWLEY, Chief Medical Officer and Executive Vice President, American Cancer Society, Atlanta, GA

MICHAEL A. CALIGIURI, Director, Ohio State Comprehensive Cancer Center, Columbus, OH, and President, Association of American Cancer Institutes

RENZO CANETTA, Vice President, Oncology Global Clinical Research, Bristol-Myers Squibb, Wallingford, CT

MICHAELE CHAMBLEE CHRISTIAN, Retired, Washington, DC

WILLIAM DALTON, President, CEO, and Center Director, Moffitt Cancer Center, Tampa, FL, and Chair, AACR Committee on Science Policy and Legislative Affairs

_________________

1 Institute of Medicine forums and roundtables do not issue, review, or approve individual documents. The responsibility for the published workshop summary rests with the workshop rapporteurs and the institution.

Page viii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

 

WENDY DEMARK-WAHNEFRIED, Associate Director for Cancer Prevention and Control, University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, AL

ROBERT ERWIN, President, Marti Nelson Cancer Foundation, Davis, CA

ROY S. HERBST, Chief of Medical Oncology, Yale Cancer Center, New Haven, CT

THOMAS J. KEAN, President and CEO, C-Change, Washington, DC

DOUGLAS R. LOWY, Deputy Director, National Cancer Institute, Bethesda, MD

DANIEL R. MASYS, Affiliate Professor, Biomedical Informatics, University of Washington, Seattle, WA

MARTIN J. MURPHY, Chief Executive Officer, CEO Roundtable on Cancer, Durham, NC

BRENDA NEVIDJON, Clinical Professor and Specialty Director, Nursing & Healthcare Leadership, Duke University School of Nursing, Durham, NC, and Past President, Oncology Nursing Society

STEVEN PIANTADOSI, Director, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA

LISA C. RICHARDSON, Associate Director for Science, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA

YA-CHEN TINA SHIH, Director, Program in the Economics of Cancer, University of Chicago, Chicago, IL

ELLEN SIGAL, Chairperson and Founder, Friends of Cancer Research, Washington, DC

STEVEN STEIN, Senior Vice President, US Clinical Development and Medical Affairs, Novartis Oncology, East Hanover, NJ

JOHN A. WAGNER, Vice President, Clinical Pharmacology, Merck and Company, Inc., Rahway, NJ

RALPH R. WEICHSELBAUM, Chair, Radiation and Cellular Oncology, and Director, Ludwig Center for Metastasis Research, The University of Chicago Medical Center, Chicago, IL

JANET WOODCOCK, Director, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

National Cancer Policy Forum Staff

SHARYL J. NASS, Director, National Cancer Policy Forum

LAURA LEVIT, Program Officer

ERIN BALOGH, Associate Program Officer

NIHARIKA SATHE, Research Assistant (until March 2012)

PAMELA LIGHTER, Research Assistant (from March 2012)

MICHAEL PARK, Senior Program Assistant

PATRICK BURKE, Financial Associate

SHARON B. MURPHY, Scholar in Residence

ROGER HERDMAN, Director, Board on Health Care Services

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

 

This Page is Blank

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

Reviewers

This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the National Research Council’s Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the process. We wish to thank the following individuals for their review of this report:

OTIS W. BRADLEY, Chief Medical Officer and Executive Vice President, American Cancer Society, Atlanta, GA

ELIZABETH A. PLATZ, Professor and Martin D. Abeloff, MD Scholar in Cancer Prevention, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

THOMAS WADDEN, Director, Center for Weight and Eating Disorders, University of Pennsylvania, Philadelphia, PA

RENA WING, Professor and Director, Weight Control and Diabetes Research Center, Brown University, Providence, RI

Although the reviewers listed above have provided many constructive comments and suggestions, they did not see the final draft of the report

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×

before its release. The review of this report was overseen by Melvin Worth. Appointed by the Institute of Medicine, he was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.

Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R1
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R2
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R3
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R4
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R5
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R6
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R7
Page viii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R8
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R9
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R10
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R11
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R12
Page xiii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R13
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R14
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R15
Suggested Citation:"Front Matter." Institute of Medicine. 2012. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/13348.
×
Page R16
Next: Workshop Summary »
The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary Get This Book
×
Buy Paperback | $39.00 Buy Ebook | $31.99
MyNAP members save 10% online.
Login or Register to save!
Download Free PDF

Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011.

The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide.

The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer.

  1. ×

    Welcome to OpenBook!

    You're looking at OpenBook, NAP.edu's online reading room since 1999. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website.

    Do you want to take a quick tour of the OpenBook's features?

    No Thanks Take a Tour »
  2. ×

    Show this book's table of contents, where you can jump to any chapter by name.

    « Back Next »
  3. ×

    ...or use these buttons to go back to the previous chapter or skip to the next one.

    « Back Next »
  4. ×

    Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book.

    « Back Next »
  5. ×

    Switch between the Original Pages, where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text.

    « Back Next »
  6. ×

    To search the entire text of this book, type in your search term here and press Enter.

    « Back Next »
  7. ×

    Share a link to this book page on your preferred social network or via email.

    « Back Next »
  8. ×

    View our suggested citation for this chapter.

    « Back Next »
  9. ×

    Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available.

    « Back Next »
Stay Connected!