every state were of the quality delivered by the highest-performing state, an estimated 75,000 fewer deaths would have occurred across the country in 2005. Current waste diverts resources from productive use, resulting in an estimated $750 billion loss in 2009. It is only through shared commitments, with a supportive policy environment, that the opportunities afforded by science and information technology can be captured to address the health care system’s growing challenges and to ensure that the system reaches its full potential. The nation’s health and economic futures—best care at lower cost—depend on the ability to steward the evolution of a continuously learning health care system.

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