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Front Matter (R1-R4)

Introduction (1-4)

Research Protocol for Clinical Evaluation (5-8)

Exposures and Mechanisms (9-10)

Epidemiology (11-12)

Key Concepts: Chemical Sensitization (13-34)

Multiple Chemical Sensitivity - What is It? (35-40)

Case Definitions for Multiple Chemical Sensitivity (41-46)

Allergy and Multiple Chemical Sensitivities (MCS) Distinguished (47-64)

Design of Animal Models to Probe the Mechanisms of Multiple Chemical Sensitivity (65-76)

Antigen Specific and Antigen Non-Specific Immunization (77-88)

Neuropsychiatric and Biopsychosocial Mechanisms in Multiple Chemical Sensitivity: An Olfactory-Limbic System Model (89-108)

Neurobehavioral and Psychosocial Aspects of Multiple Chemical Sensitivity (109-116)

Diagnostic Markers of Multiple Chemical Sensitivity (117-138)

Possible Mechanisms for Multiple Chemical Sensitivity: The Limbic System and Others (139-150)

Developing Clinical Research Protocols for Studying Chemical Sensitivities (151-154)

Immunological Mechanisms of Disease and the Multiple Chemical Sensitivity Syndrome (155-168)

Considerations for the Diagnosis of Chemical Sensitivity (169-192)

Occupational Asthma (193-196)

List of Contributors (197-198)

List of Participants (199-202)