. "B CATALOG OF EMERGING INFECTIOUS DISEASE AGENTS." Emerging Infections: Microbial Threats to Health in the United States. Washington, DC: The National Academies Press, 1992.
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Emerging Infections: Microbial Threats to Health in the United States
INFECTIOUS AGENT
Chikungunya virus, a single-stranded RNA virus
MODE OF TRANSMISSION
bite of an infective Aedes mosquito
not directly transmitted from person to person
DISTRIBUTION
primarily Africa, South Asia, and the Philippines
INCUBATION PERIOD
3 to 12 days
TREATMENT
supportive only
PREVENTION AND CONTROL
mosquito control in endemic areas
a live, attenuated vaccine is being tested
FACTORS FACILITATING EMERGENCE
unknown
Crimean-Congo Hemorrhagic Fever Virus
DISEASE(S) AND SYMPTOMS
Crimean-Congo hemorrhagic fever
abrupt onset of fever, headache, chills, photophobia, myalgia, and abdominal pain
nausea, vomiting, and diarrhea may be present; rash is common
infection to death ratio is estimated at 25:1
in pregnant women, infection is severe and often results in death
DIAGNOSIS
isolation of the virus from cerebrospinal fluid, blood, or other tissues