. "B CATALOG OF EMERGING INFECTIOUS DISEASE AGENTS." Emerging Infections: Microbial Threats to Health in the United States. Washington, DC: The National Academies Press, 1992.
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Emerging Infections: Microbial Threats to Health in the United States
DIAGNOSIS
isolation of virus from blood
serologic studies (ELISA, etc.)
INFECTIOUS AGENT
dengue viruses, serotypes 1-4 (all four types can cause dengue hemorrhagic fever)
MODE OF TRANSMISSION
bite of an infective Aedes aegypti or Aedes albopictus mosquito
not directly transmitted from person to person
Distribution
epidemic and endemic in tropical and subtropical areas of Africa, the Americas, Asia, Oceania, and Australia
widespread in the Caribbean basin
INCUBATION PERIOD AND COMMUNICABILITY
3 to 14 days, average 7 to 10 days
while disease is not transmitted from person to person, patients can be infective for mosquitoes from the day before to the end of the febrile period (5 to 7 days)
TREATMENT
supportive only
PREVENTION AND CONTROL
control of mosquitoes
vaccine is not yet available
FACTORS FACILITATING EMERGENCE
lack of effective mosquito control
increased urbanization in the tropics
increased air travel
Filoviruses (Marburg, Ebola)
DISEASE(S) AND SYMPTOMS
sudden onset of fever, headache, joint and muscle pain, followed by sore throat, diarrhea, abdominal pain, vomiting, and rash
