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Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Casuality (1994)
Institute of Medicine (IOM)

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Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality

DT/Td/T

Measlesa

Mumpsa

OPV/IPVb

Hepatitis B

H. influenzae typeb

Erythema multiforme

Transverse myelitis

Thrombocytopenia

 

 

 

 

Guillain-Barré syndrome

Anaphylaxisd

 

 

 

 

Thrombocytopenia

 

 

 

 

 

Insulin-dependent diabetes mellitus

 

 

 

 

Category 3: The Evidence Favors Rejection of a Causal Relation

Encephalopathye

 

 

 

 

Early onset H. influenzaeb disease (conjugate vaccines)

Infantile spasms (DT only)f

 

 

 

 

 

Death from SIDS (DT only)f,g

 

 

 

 

 

Category 4: The Evidence Favors Acceptance of a Causal Relation

Guillain-Barré syndromeh

Anaphylaxisd

 

Guillain-Barré syndrome (OPV)

 

Early-onset H. influenzaeb disease in children age 18 months or older who receive their first Hib immunization with unconjugated PRP vaccine

Brachial neuritish

 

 

 

 

 

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