Protein located within liver cells (and possibly other cells) that interacts with TCDD and other molecules and with specific sites on DNA to regulate DNA.
Altered lipid metabolism.
An interference in the body's normal processes in breaking down or building up the molecules that are fat-soluble, including fatty acids, glycerides, waxes, steroids, and certain vitamins.
Absence of the cranial vault, with cerebral hemispheres completely missing or reduced to small masses attached to the base of the skull.
Absence of an immune reaction to a specific antigen.
Loss or impairment of the ability to use or comprehend words usually resulting from a brain lesion.
Loss or impairment of the ability to execute complex coordinated movements, without impairment of the muscles or senses.
A disease involving a humoral or cell-mediated immunity to the tissues of one's own body. A failure of the immune system to discriminate between self and respondent.
A procedure for estimating the nature, constitution, or potency of a material by statistically analyzing the reaction that follows its application to living matter.
Fixed-wing aircraft used in Operation Ranch Hand during the Vietnam conflict to spray herbicides.
Dimethylarsinic acid, a contact herbicide used during the Vietnam conflict in Agent Blue.
A general term used to indicate a malignant tumor that expands locally by invasion or systemically by metastasis.
Disorders of the heart and blood vessels or the circulation of blood through the body.
An epidemiologic study in which persons are selected because they have a specific disease or other outcome (cases) and are compared to a control (referent comparison) group to evaluate whether there is a difference in their reported frequency of exposure to possible disease risk factors. Also termed a retrospective study or case-referent study.