Holman, R. T. 1968. Essential fatty acid deficiency. Prog. Chem. Fats Other Lipids 9:275–348.

Horio, F., K. Ozaki, A. Yoshida, S. Makino, and Y. Hayashi. 1985. Requirement for ascrobic acid in a rat mutant unable to synthesize ascorbic acid. J. Nutr. 115:1630–1640.

International Council for Laboratory Animal Science. 1987. ICLAS Guidelines on the Selection and Formulation of Diets for Animals in Biomedical Research, M. E. Coates, ed. London: International Council for Laboratory Animal Science.

Jenness, R., E. C. Birney, and K. L. Ayaz. 1980. Variation of L-gulonolactone oxidase activity in placental mammals. Comp. Biochem. Physiol. B 67:195–204.

Johnston, P. V., and K. L. Fritsche. 1989. Nutritional methodology in dietary fat and cancer research. Pp. 9–25 in Carcinogenesis and Dietary Fat, S. Abraham, ed. Boston: Kluwer Academic.

Knapka, J. J. 1983. Nutrition. Pp. 51–67 in The Mouse in Biomedical Research . Vol. 3, H. L. Foster, J. D. Small, and J. G. Fox, eds. New York: Academic Press.

Knapka, J. J. 1985. Formulation of diets. Pp. 45–59 in Methods for Nutritional Assessment of Fats, J. Beare-Rogers, ed. Champaign, Ill.: American Oil Chemists Society.

Knapka, J. J., K. P. Smith, and R. J. Judge. 1974. Effect of open and closed formula rations on the performance of three strains of laboratory mice. Lab. Anim. Sci. 24:480–487.

Lee, Y. C. P., J. T. King, and M. B. Visscher. 1953. Strain difference in vitamin E and B₁₂ and certain mineral trace-element requirements for reproduction in A and Z mice. Am. J. Physiol. 173:456–458.

Ley, F. J., J. Bleby, M. E. Coates, and S. J. Patterson. 1969. Sterilization of laboratory animal diets using gamma radiation. Lab. Anim. 3:221–254.

Luecke, R. W., and P. J. Fraker. 1979. The effect of varying zinc levels on growth and antibody mediated response in two strains of mice. J. Nutr. 109:1373–1376.

Mizushima, Y., T. Harauchi, T. Yoshizaki, and S. Makino. 1984. A rat mutant unable to synthesize vitamin C. Experientia 40:359–361.

National Institutes of Health. 1985. Guide for the Care and Use of Laboratory Animals, Publication No. 86–23. Bethesda, Md.: National Institutes of Health.

National Research Council. 1973. Effect of Processing on the Nutritional Value of Feeds. Washington, D.C.: National Academy Press.

National Research Council. 1976. Atlas of United States and Canadian Feeds. Washington, D.C.: National Academy Press.

National Research Council. 1980. Mineral Tolerance of Domestic Animals. Washington, D.C.: National Academy Press.

National Research Council. 1982. United States—Canadian Tables of Feed Composition. Washington, D.C.: National Academy Press.

National Research Council. 1984. Nutrient Requirements of Beef Cattle, Sixth Revised Edition. Washington, D.C.: National Academy Press.

National Research Council. 1985. Nutrient Requirements of Sheep, Sixth Revised Edition. Washington, D.C.: National Academy Press.

National Research Council. 1987. Vitamin Tolerance of Animals. Washington, D.C.: National Academy Press.

National Research Council. 1988. Nutrient Requirements of Swine, Ninth Revised Edition. Washington, D.C.: National Academy Press.

National Research Council. 1989. Nutrient Requirements of Dairy Cattle, Sixth Revised Edition. Washington, D.C.: National Academy Press.

Navia, J. M. 1977. Animal Models in Dental Research. Tuscaloosa, Ala.: University of Alabama Press.

Pfast, H. B., ed. 1976. Feed Manufacturing Technology. North Arlington, Va.: Feed Production Council, American Feed Manufacturing Association.

Pleasants, J. R. 1984. The germ-free animal fed chemically defined ultrafiltered diet. Pp. 91–109 in The Germ-Free Animal in Biomedical Research. Laboratory Animals Handbook 9, M. E. Coates, and B. E. Gustafsson, eds. London: Laboratory Animals Ltd.

Pleasants, J. R., M. H. Johnson, and B. S. Wostmann. 1986. Adequacy of chemically defined, water-soluble diet for germ-free BALB/c mice through successive generations and litters. J. Nutr. 116:1949–1964.

Pleasants, J. R., B. S. Reddy, and B. S. Wostmann. 1970. Qualitative adequacy of chemically defined liquid diet for reproducing germ-free mice. J. Nutr. 100:498–508.

Quinn, M. R., and M. M. Chan. 1979. Effect of vitamin B₆ deficiency on glutamic acid decarboxylase activity in rat olfactory bulb and brain. J. Nutr. 109:1694–1702.

Rao, G. N., and J. J. Knapka. 1987. Contaminant and nutrient concentrations of natural-ingredient rat and mouse diet used in chemical toxicology studies. Fund. Appl. Toxicol. 9:329–338.

Snyder, D. L., and B. Towne. 1989. The effect of dietary restriction on serum hormone and blood chemistry changes in aging Lobund-Wistar rats. Prog. Clin. Biol. Res. 287:135–146.

Slinger, S. J. 1973. Effect on pelleting and crumbling methods on the nutritional value of feeds. Pp. 48–66 in Effect of Processing on the Nutritional Value of Feeds: Proceedings. Washington, D.C.: National Academy of Sciences.

Stevens, C. E. 1988. Comparative physiology of the vertebrate digestive system. New York: Cambridge University Press.

Weindruch, R., and R. L. Walford. 1988. The Retardation of Aging and Disease by Dietary Restriction. Springfield, Ill.: Charles C Thomas.

Williams, L. P., J. B. Vaughn, A. Scott, and V. Blanton. 1969. A ten-month study of salmonella contamination in animal protein meals. J. Am. Vet. Med. Assoc. 155:167–174.

Wise, A. 1982. Interaction of diet and toxicity—The future role of purified diet in toxicological research. Arch. Toxicol. 50:287–299.

Wostmann, B. S. 1975. Nutrition and metabolism of the germ-free animal. World Rev. Nutr. Dietet. 22:40–92.

Wretlind, K. A. J., and W. C. Rose. 1950. Methionine requirement for growth and utilization of its optical isomers. J. Biol. Chem. 187:697–703.

Yu, B. P. 1990. Food restriction: Past and present status. Rev. Biol. Res. Aging 4:349–371.

Zimmerman, D. R., and B. S. Wostmann. 1963. Vitamin stability in diets sterilized for germ-free animals. J. Nutr. 79:318–322.

Front Matter (R1-R14)

Overview (1-2)

1 General Considerations for Feeding and Diet Formulation (3-10)

2 Nutrient Requirements of the Laboratory Rat (11-79)

3 Nutrient Requirements of the Mouse (80-102)

4 Nutrient Requirements of the Guinea Pig (103-124)

5 Nutrient Requirements of the Hamster (125-139)

6 Nutrient Requirements of the Gerbil (140-143)

7 Nutrient Requirements of the Vole (144-148)

Appendix (149-153)

Authors (154-156)

Index (157-176)