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Prudent Practices in the Laboratory: Handling and Disposal of Chemicals
PREPARATION OF NEW LCSSs
All of the information required for the preparation of new LCSSs should be available in the sources discussed in Chapter 3. The following directions should be helpful in preparing specific sections of new LCSSs:
Odor: Information on odor and odor thresholds can be found in NIOSH Guidelines, Royal Society Chemical Safety Data Sheets, and in the AIHA publication "Odor Thresholds for Chemicals with Established Occupational Health Standards."
Toxicity data: LD50 and LC50 values can be found in MSDSs and other sources listed in Chapter 3. Exposure limits are included in MSDSs and are listed in the ACGIH Threshold Limit Value booklet, which is updated annually.
Major hazards: This section should provide key words indicating only the most important potential hazards associated with the title substance.
Toxicity: The first paragraph of this section should discuss acute toxicity hazards using plain language. Symptoms of exposure by inhalation, skin contact, eye contact, and ingestion should be separately described, and the degree of hazard of the substance should be identified as "high," "moderate," or "low," as discussed in Chapter 3. The paragraph should indicate whether there are adequate warning properties for the substance. The second paragraph should address chronic toxicity. For potential carcinogens, whether the substance is classified as an OSHA ''select carcinogen" should be indicated.
Flammability and explosibility: This section should indicate the NFPA rating for the substance, explosion limits, toxic substances that may be produced in a fire, and the type of fire extinguisher appropriate for fighting fires.
Storage and handling: This section should make reference to the appropriate sections of Chapter 5 and should also highlight any special procedures of particular importance in work with the title substance.
SECTIONS INCLUDED IN LCSSs
Each of the 88 LCSSs supplied in this appendix includes those of the following sections that apply to the title substance: