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OCR for page 147
Index
A
AAAAI. See American Academy of
Allergy, Asthma, and Immunology
Abscesses, 34
Access control barriers, 108-109, 126
Accidents, 15, 25
Accountability and responsibility, 4, 15-17
Acoustical hazards. See Hazards, physical
Administration and management, 2, 4, 8,
16-18, 22, 121. See also
Commitment, element of
consistency in, 4, 13, 15, 124
procedures, 6, 107
style and structure of, 23
Adverse-reaction report data, 27, 29
Aerosol transmission, 45, 48-49, 55-56,
73, 76, 85
African green monkeys, 46, 70, 78
Agricultural Research Service (ARS), 26
AIDS. See Susceptibility of employees
Airborne exposures. See Aerosol
transmission
Air hoods. See Respirators
Airway hyperresponsiveness. See Asthma
Allergens. See Hazards
Allergic conjunctivitis, 53
147
Allergic rhinitis, 53-54, 59-60
Amebiasis, 98-99
American Academy of Allergy, Asthma,
and Immunology (AAAAI), 64
American National Standards Institute
(ANSI), 117
Amphibians, 60
Anaphylaxis, 52-53, 64
Anesthetic gases, 42-43
Animal and Plant Health Inspection
Service (APHIS), 26
Animal biosafety levels, 45, 81
Level 2 practices, 49, 72, 77, 80, 88,
90, 92, 94, 100-101
Level 3 practices, 49, 68, 73, 83, 86,
91
Level 4 practices, 48, 70
Animal care and use programs, 4, 18-20,
22, 112. See also Site inspections
addressing occupational health in, 8
progress in, 1
Animal-control measures, 79
Animals. See also individual species
species-specific responses to, 12, 107
wild, 13, 66-67, 79-81, 101-102 (~See
also Rodents, wild)
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148
ANSI. See American National Standards
Institute (ANSI)
APHIS. See Animal and Plant Health
Inspection Service (APHIS)
Approvals required, 21, 39, 48
Arboviral infections, 45-46, 80-81
ARS. See Agricultural Research Service
Arthritis, septic, 34
Arthropod-borne viruses. See Arboviral
infections
Arthropod infestations, 101 - 102, 104- 105
Asthma, 51, 53-54, 57-63
Atopy, 54
Authorizations required. See Approvals
required
B
Back injuries, 40
Bacterial pathogens, 46-47, 85-95
Balantidiasis, 99
Benign epidermal monkeypod, 73-74
Biological hazards. See Hazards
Biological safety cabinets, 109- 111, 117
Biosafety in Microbiological and
Biomedical Laboratories, 45, 48,
125
Biosafety in the Laboratory: Prudent
Practices for the Handling and
Disposal of Infectious Materials, 48
Biosafety levels. See Animal biosafety
levels
Birds, 46, 59, 81-82, 85, 87-88, 93, 104
Bites and scratches. See Hazards, physical
Bloodborne pathogens. See Hazards,
biological
Breathing, difficulty in, 53
Brucellosis, 34, 46, 90-91
Bubonic plague, 89-90
Bursitis, 40
B-virus infection, 27, 34, 46, 66-68
C
Cage cleaning. See Housekeeping
practices
INDEX
Cages, 62, 109-110
Campylobacteriosis, 46, 92
Cardiopulmonary resuscitation, 64
Carpal-tunnel syndrome, 40
Cats, 57-58, 71, 79, 81, 83-85, 95-97, 99
100, 102-104
Cat-scratch fever, 34, 83-84
Cattle, 46, 58-59, 85, 91
Cellulitis, 34
Centers for Disease Control and
Prevention (CDC), 5, 25, 45, 66,
68, 72
Cercopithecine herpesvirus 1 (CHV1~. See
B-virus infection
Chemical fume hoods. See Respirators
Chemical inventory data, 25
Chemical restraint, 15, 33, 35, 68
Chemicals, hazardous. See Hazards,
chemical
Chemoprophylaxis, 86, 88
Chlamydiosis. See Psittacosis
Choriomeningitis, lymphocytic. See
Lymphocytic choriomeningitis
CHV1. See B-virus infection
Cleaning hazards. See Housekeeping
practices
Collaboration. See Coordination within
programs
Commitment, element of, 4, 8, 13, 15, 23
24, 121
Compliance Database data, 29-30
Compliance issues, 17, 23, 107. See also
Approvals required; Regulatory
requirements
Compressed-gas cylinders, 36
Computer links, 120
Confidentiality, 118
Conjunctivitis, allergic, 53
Consultants, using, 30-31, 64, 129, 132
Contagious ecthyma, 34, 74-75
Coordination within programs, 2-5, 8, 13,
15, 18,21,65
Coxiella burnetii. See Q fever
Coyotes, 46
Credibility issues, 15
Cryptosporidiosis, 97-98
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INDEX
Custodial service. See Housekeeping
practices
Cylinders, compressed-gas, 36
D
Deer, 59
Dermatitis
atopic, 54
contact, 59
contagious pustular (See Orf disease)
Dermatomycosis, 47, 99- 100
Disinfectants, 42-43
Documentation, 118
Dogs, 46-47, 58, 79, 81, 84-85, 90-91, 95,
97, 99-100, 102-105
Dust-mist respirators. See Respirators
E
Ebola-Reston virus, 69
Ebola-virus infection, 68-70
Ecthyma, contagious. See Orf disease
Ectoparasitic infestations, 34, 74-75
Eczema. See Dermatitis, atopic
Edema, laryngeal, 53
Education and training, 4, 6, 12-14, 17,
34, 39-40, 62-63, 65, 114-116
Electric hazards. See Hazards,
physical
Electromagnetic radiation. See Ionizing
radiation
ELISA. See Enzyme-linked
immunosorbent assay
Emergency procedures, 6, 120-121. See
also Accidents
Employees
defined (See Occupational health and
safety programs, participation in)
et risk, 4, 12, 17, 22, 111, 120, 129-
130 (See also Hazards, perceived;
Screening programs; Susceptibility
of employees)
Endocarditis, 34
Engineering controls, 108- 110
Enteric yersiniosis, 95
149
Envenomation, 34
Environmental health and safety
programs, 2, 4, 6-7, 9, 18, 21-22,
29, 106
Environmental Protection Agency, 2
Enzyme-linked immunosorbent assay
(ELISA), 61
Epinephrine, self-administered, 64
Episodic health evaluations, 10, 29, 131
Equipment, dangerous, 40-41
Equipment performance, 6, 25, 116-118
Ergonomic hazards, 40, 108. See also
Hazards, physical
Evaluation
program, 6, 121-122, 133-134
of workers, 63-64, 124, 130-131, 133
(See also Episodic health
evaluations)
Experimentation. See Research
Exposure, 4, 13-14, 43, 55, 125, 127
controlling, 4, 25, 108-114
F
Facilities, 17, 107-108
design, 6, 62
operation, 6
Federal Bureau of Labor Statistics data,
27-28
Ferrets, 80, 85
Filoviruses. See Ebola-Reston
Filter-top cages, 62, 109-110
Fires. See Hazards, physical
First-aid log data, 27, 29, 134
First Report of Injury or Illness data, 27-
28
Fish, 60
Flammable materials, classes of, 35
Flea-control measures, 84
Fleas. See Insects
Flight zone, 33
Fowl. See Birds
Fume hoods. See Respirators
Funding agencies, requirements of, 2
Fungal pathogens, 34, 47, 99- 101
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150
G
Gene therapy research, 48. See also
Guidelines for Research Involving
Recombinant DNA Molecules
Gerbils, 56
Giardiasis, 97
Goats, 46-47, 74-75, 85
Guide for the Care and Use of Laboratory
Animals, 63
Guidelines. See Rules and guidelines
Guidelines for Research Involving
Recombinant DNA Molecules, 48,
124
Guinea pigs, 46-47, 56, 95, 104
H
Hamsters, 46, 102
Hantavirus infection, 34, 71-72
Hazard Communication Standard, 42
Hazard information, sources of, 25-26
Hazards. See also Laboratory safety
allergens, 3, 5-6, 24, 26, 51-64 (See
also Evaluation, of workers)
mechanisms of, 53-54
preventive measures, 60-64
biological, 7, 127 (See also Approvals
required)
infectious agents, 2, 7, 12-13, 44-48,
124
radiation sources, 12, 20-21, 36-39
chemical, 2, 5, 12-14, 24, 42-44
defined, 26
identifying (See Risk Assessment)
novel, 47
perceived, 24
physical, 3, 5, 7, 24, 26, 32-41, 127
(See also Housekeeping practices)
bites and scratches, 33-34, 44,
52-53
electricity, 36
fires, 35, 118
noise, 41
trauma, 40
protocol-related (See Research,
protocol-related hazards of)
INDEX
undetected, 14, 31
unknown, 44, 66
zoonoses, 3, 6, 14, 20, 44-45, 65-105
HBV. See Hepatitis-B virus (HBV)
Health and safety risks. See Hazards
Health Research Extension Act of 1986,
124
Helminth-parasite infections, 101-103
Hemorrhagic fever. See Hantavirus
infection; Lymphocytic
choriomeningitis (LCM) virus
infection
HEPA filtration. See High-efficiency-
particulate-air-filtered (HEPA-
filtered) laminar-flow ventilation
Hepatitis A virus, 46, 76-77
Hepatitis B virus (HBV), 7, 77-78, 124
Hepatitis C, D, and E viruses, 77-78
High efficiency-particulate-air-filtered
(HEPA-filtered) laminar-flow
ventilation, 62, 110- 112, 117
High-pressure lines, 36
Hives. See Anaphylaxis; Edema,
laryngeal; Uticaria, contact
Hoods. See Respirators
Horses, 59
Housekeeping practices, 39, 110, 112-113
Human-influenza viruses, 80
Human-resources function, 22
Husbandry, animal. See Animal care and
use programs
Hygiene, personal, 48-50, 63, 65, 111 - 112
Hypersensitivity, 54, 59
I
IACUC. See Institutional animal care and
use committee
ILAR. See Institute of Laboratory Animal
Resources
Immunizations. See Vaccinations
Immunotherapy, 64
Influenza-virus infections, 80
Information management, 6, 118- 120. See
also Occupational health and safety
information, sources of
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INDEX
Insects, 58, 60, 83-84
Inspections. See Site inspections
Institute of Laboratory Animal Resources,
25
Institutional animal care and use
committee (IACUC), 2, 5, 18-21,
107, 121
Institutions
categories of, 1-2
functional parts of, 4, 16-22
mission, 4, 123
obligations of, 1, 16, 124
Interactions between departments, 18-19,
130, 134. See also Coordination
within programs
Ionizing radiation, 38-39. See also
Hazards, biological
IPAC. See Public Health Service Advisory
Committee on Immunization
Practices
Irradiation. See Ionizing radiation
J
Janitorial service. See Housekeeping
practices
Job descriptions, 12, 22
L
Laboratory safety, 2, 42, 65, 85, 110-114
Laboratory Safety: Principles and
Practices, 48
Laboratory standard. See Occupational
Exposure to Hazardous Chemicals
in Laboratories
Laryngeal edema, 53
Laser radiation, 37-38. See also Hazards,
biological
Lassa fever, 72
LCM. See Lymphocytic choriomeningitis
(LCM) virus infection
Lentivirus infections. See Simian
immunodeficiency virus (SIV)
infection
Leptospirosis, 47, 91-92
151
Lifting injuries, 40
Lighting, low, 36
Livestock, 46, 99. See also individual
species
Lymphocytic choriomeningitis (LCM)
virus infection, 14, 46, 65, 72-73
M
Macaques, 46, 69, 74, 78, 85, 125
Machinery, dangerous, 40-41
Management. See Administration and
management
Marburg-virus disease, 46, 70
Material-Safety Data Sheets (MSDSs), 25,
35, 127
Measles, 75-76
Medical-surveillance programs, 78, 124,
134
Meningitis, 34
Mice, 46-47, 55-56, 91, 102, 104
Monitoring, 4, 13, 15, 22, 61, 116. See
also Recordkeeping
of effluent, 118
Monkeypox, 73-74
Monkeys, various, 76-78. See also African
green monkeys; Macaques
Morbidity and Mortality Weekly Report,
66
MSDSs. See Material-Safety Data Sheets
Multidisciplinary approaches, 9
N
National Animal Disease Center (NADC),
26
National Center for Infectious Diseases,
72-73
National Fire Protection Association
(NFPA), 35
National Institute for Occupational Safety
and Health (NIOSH), 25, 40, 63
National Institutes of Health (NIH), 5, 26,
45, 68, 124-125
National Research Council, 1, 5
recommendations by, 8-10
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152
National Safety Council (NSC), 38
National Sanitation Foundation (NSF),
117
Near-miss reports, 131 - 132
Neuropathia endemica. See Hantavirus
infection
Newcastle disease, 76
NFPA. See National Fire Protection
Association
NIH. See National Institutes of Health
NIOSH. See National Institute for
Occupational Safety and Health
Noise. See Hazards, physical
Nonparticulate radiation. See Ionizing
radiation
NSC. See National Safety Council
NSF. See National Sanitation Foundation
o
Occupational Exposure to Hazardous
Chemicals in Laboratories, 42
Occupational health and safety
information, sources of, 26-30
Occupational health and safety programs,
18, 22
costs of, 5, 30-31
developing, 4-5, 17, 23-31
elements of, 6, 106-122
participation in, 9, 11 - 13, 123- 124
Occupational health and safety risks. See
Hazards
Occupational health-care service, 6-7,
123-134
activities of, 129-133
limitations of, 133
responsibilities of, 125-129
Occupational health log data, 27, 29, 119
Occupational Safety and Health
Administration (OSHA), 2, 7, 21,
25, 35, 41, 114, 121, 124
Occupations, categories of, 2
Orf disease, 34, 74-75
Orientation. See Education and training
Ornithosis. See Psittacosis
Orthopox virus. See Monkeypox
INDEX
OSHA. See Occupational Safety and
Health Administration (OSHA)
OSHA Form 101. See Supplementary
Record of Occupational Injury or
Illness (OSHA Form 101) data
OSHA 200 log data, 27-29, 119-120, 127,
134
Osteomyelitis, 34
p
Paramyxovirus infection. See Newcastle
disease
Parrot fever. See Psittacosis
Personal protective equipment, 14, 17, 41,
49, 63, 111-114
Pesticides, 42-43
Physical examinations, 7, 9-10. See also
Evaluation, of workers
Physical hazards. See Hazards
Pigs. See Swine
Plague, 89-90
Pneumonitis, 59
Poxvirus diseases. See Benign epidermal
monkeypod; Monkeypox; Orf
disease
Preexisting conditions, 60-61
Primates (nonhuman), 33, 46-47, 58, 76-
77, 85-87, 94-95, 97, 99, 102-103
Priority-setting of hazards, 24
Professional societies, 25
Protective equipment. See Personal
protective equipment
Protozoal pathogens, 95-99
Prudent Practices in the Laboratory:
Handling and Disposal of
Chemicals, 42, 44
Psittacosis, 46, 87-88
Public Health Service, 7
Advisory Committee on Immunization
Practices (IPAC), 132
Public Health Service Policy on Humane
Care and Use of Laboratory
Animals, 124
Pulmonary function, monitoring, 61, 64
Pustular dermatitis. See Orf disease
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INDEX
Q
Q fever, 14, 46, 65, 81-83
R
Rabbits, 47, 56, 85, 95, 99, 103-105
Rabies virus, 34, 79-80
Radiation, ionizing. See Ionizing
radiation
Radioallergosorbent test (RAST), 61
Radioisotopes. See Hazards, biological
Ranking hazards, 26
RAST. See Radioallergosorbent test
Rat-bite fever, 34, 47, 88-89
Rats, 47, 54-55, 91, 102, 104
Recordkeeping, 4, 13, 15, 116, 132
Refresher training. See Education and
. .
trammg
Regulatory requirements, 2, 5, 7, 24, 112,
127
Reporting requirements, 15, 20, 131-132
Reptiles, 60, 93. See also Envenomation
Research,4,18,21
complexity of, 43-44
protocol-related hazards of, 5, 7, 43-50
reviews of protocols, 25, 115-116
Resource development. See Occupational
health and safety programs, costs of
Respirators, 63, 109-111, 114
Responsibility and accountability, 4, 15
17
Restraint, 68, 113. See also Chemical
restraint
Rhesus monkeys, wild-caught, 67
Rhinitis, allergic, 53-54, 59-60
Rickettsial pathogens, 46, 81-85
Risk
assessment of, 4-9, 13-14, 20, 24-30,
125, 127
defined, 26
Rodents, 99. See also Guinea pigs; Mice;
Rats
wild, 71-72, 84, 89-90, 104-105
Rubeola. See Measles
Rules and guidelines, 4, 13- 15
153
S
Safety awards, 23
Safety bulletins and reports, 25
Safety cabinets, 109-111, 117
Salmonellosis, 47, 92-94
SALS. See Subcommittee on Arbovirus
Laboratory Safety
Scratches. See Hazards, physical
Screening programs, 60-61, 126
SDS. See Supplementary Data System
(SDS) data
Sedation. See Chemical restraint
Septic arthritis, 34
Serum collection, 7, 9-10, 126, 132-133
Sharps, controlling, 34-35, 48, 111
Sheep, 46, 59, 74-75, 81-82, 85
Shigellosis, 47, 94
Simian immunodeficiency virus (SIV)
infection, 46, 78-79
Site inspections, 20-21, 25, 116, 134. See
also Animal care and use programs
SIV. See Simian immunodeficiency virus
(SIV) infection
Snake bite, 34
Sporotrichosis, 47, 100-101
Stomatitis virus, 46
Subcommittee on Arbovirus Laboratory
Safety (SALS), 45, 70
Supplementary Data System (SDS) data,
27-28
Supplementary Record of Occupational
Injury or Illness (OSHA Form 101)
data, 28-29
Surveillance programs. See Medical-
surveillance programs
Susceptibility of employees, 7, 127-128
AIDS-related, 98
Swine, 46, 58, 85, 90-91, 97, 99, 103-104
T
Tanapox. See Benign epidermal
monkeypod
Tennis elbow, 40
Tenosynovitis, 34
Tetanus, 34
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154
Tissue-preserving chemicals, 42-43
Toxic chemicals, 42. See also Hazards,
chemical
Toxoplasmosis, 95-97
Training. See Education and training
Transgenic animals, 48
Transplantation, 66
Tuberculosis, 47, 85-87
Tularemia, 34
U
Ultrasonography, hazards associated with,
41
Ultraviolet (UV) radiation. See also
Hazards, biological
biocidal use of, 117
classification of, 36-37
Urticaria, contact, 52-53, 60
U.S. Army Medical Research Institute for
Infectious Disease (USAMRIID),
83
U.S. Nuclear Regulatory Commission, 39
USAMRIID. See U.S. Army Medical
Research Institute for Infectious
Disease (USAMRIID)
U V. See Ultraviolet (UV) radiation
V
Vaccinations, 74, 76-80, 87, 90, 124, 126,
132
Ventilation systems, 62, 107- 108, 117- 118
INDEX
Vesicular stomatitis virus, 46
Veterinarian, staff, 18, 20-21, 115, 127
Viral pathogens, 46, 66-81. See also
individual viruses
Visibility, impaired, 36
W
Walk-through. See Site inspections
Welts. See Urticaria, contact
Wheezing. See Edema, laryngeal
Work environment. See Exposure,
controlling
Worker compensation data, 26-28, 119,
127, 132, 134
Workplace diversity. See Occupational
health and safety programs,
participation in
Work practices. See Laboratory safety
X
Xenograft transplantation, 66
y
Yersinia infection, 95
z
Zoonoses. See Hazards
Representative terms from entire chapter:
housekeeping practices
