Vaccines for the 21st Century: A Tool for Decisionmaking

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Vaccines for the 21st Century: A Tool for Decisionmaking (2000)
Institute of Medicine (IOM)

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. "Overview of Analytic Approach and Results." Vaccines for the 21st Century: A Tool for Decisionmaking. Washington, DC: The National Academies Press, 2000.

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Vaccines for the 21st Century: A Tool for Decisionmaking

Table 4–1 Vaccine Candidates

Vaccine	Target Population	Utilization (%)	Purchase $ (per dose)	Time to Licensure	Development $ (millions)
BORRELIA
	Infants (restricted geography)	90	100	3	120
	Migrants (restricted geography)	10	100	3	120
CHLAMYDIA
	12-year-olds	50	50	15	360
COCCIDIOIDES IMMITIS
	Infants (restricted geography)	90	50	15	360
	Migrants (restricted geography)	10	50	15	360
CYTOMEGALOVIRUS
	12-year-olds	50	50	7	360
ENTEROTOXIGENIC E. COLI
	Infants	90	50	7	240
	Travelers	30	50	7	240
EPSTEIN-BARR VIRUS
	12-year-olds	50	50	15	390
HELICOBACTER PYLORI
	Infants	30	50	7	240
HEPATITIS C
	Infants	90	50	15	360
HERPES SIMPLEX VIRUS
	12-year-olds	50	50	7	240
HISTOPLASMA CAPSULATUM
	Infants (restricted geography)	90	50	15	360
	Migrants (restricted geography)	10	50	15	360
HUMAN PAPILLOMA VIRUS
	12-year-olds	50	100	7	360
INFLUENZA
	Universal (every 5 years)	30	50	7	360
INSULIN-DEPENDENT DIABETES MELLITUS (therapeutic)
	Early-stage patients	90	500	15	360